Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-04-009 ISMRM Abstract

Hippocampal Blood Flow Reserve Associated with Cognitive Function and Structural Integrity in Cerebral Small Vessel Disease

Primary: Diffusion - Microstructure
Secondary: Neuro - Other Neurodegeneration
663-04-009 · Cerebral Small Vessel Disease: Network, Glymphatic, and Blood Flow · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row D
Keywords: Cerebral small vessel disease Hippocampus Diffusion in Grey Matter 3D pCASL 3.0T
Accepted
Binglan Li 1, Lisha Nie2, Li yongmei3
1Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
2GE Healthcare, MR Research China, Beijing, China
3The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Presenting Author: Binglan Li

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References

1. 1.Wen J, Li C, Sun Z, Wang C, Zhang J, Guan X, Xu X, Wisniewski T, Ge Y. (2025 )Hippocampal subfields in aging: Sex-specific trajectories in structure and hemodynamics. Neuroimage. Aug 15;317:121343. https://doi: 10.1016/j.neuroimage.2025.121343. [doi]
2. 2.Duering M, Biessels GJ, Brodtmann A, Chen C et al. (2023) Neuroimaging standards for research into small vessel disease-advances since 2013. Lancet Neurol. Jul;22(7):602-618. https://doi: 10.1016/S1474-4422(23)00131-X. [doi]
3. 3.Johnson AC. (2023) Hippocampal Vascular Supply and Its Role in Vascular Cognitive Impairment. Stroke. Mar;54(3):673-685. https://doi: 10.1161/STROKEAHA.122.038263. [doi]
4. 4.Shahid SS, Wen Q, Risacher SL, Farlow MR, Unverzagt FW, Apostolova LG, Foroud TM, Zetterberg H, Blennow K, Saykin AJ, Wu YC. (2022) Hippocampal-subfield microstructures and their relation to plasma biomarkers in Alzheimer's disease. Brain. Jun 30;145(6):2149-2160. https://doi: 10.1093/brain/awac138. [doi]
5. 5.Chen J, Wang J, Duan K, Li X, Pan Z, Zhang J, Qin X, Hu Y, Lyu H. (2024) Selective vulnerability of hippocampal sub-regions in patients with subcortical vascular mild cognitive impairment. Brain Imaging Behav. Aug;18(4):922-929. https://doi: 10.1007/s11682-024-00881-y. [doi]
6. 6.Petersen M, Emskötter D, Nägele FL, Mayer C, Schell M, Fiehler J, Gallinat J, Kühn S, Twerenbold R, Jensen M, Thomalla G, Cheng B. (2025) Mapping the Association of Cerebral Small Vessel Disease, Gray Matter Integrity, and Cognitive Function. Neurology. Nov 11;105(9):e214215. https://doi:10.1212/WNL.0000000000214215. [doi]

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http://echo.ismrm.org/p/ISMRM2026/663-04-009