Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
669-04-002 ISMRM Abstract

Multiparametric MRI to assess the Effects of Oxygenated Hypothermic Machine Perfusion on Ex-Vivo Pancreases

Primary: Body - Pancreas
Secondary: Contrast Mechanisms - Multi-Contrast
669-04-002 · Twists and Turns: Pancreas, Cholangio, and Bowel MRI · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row J
Keywords: Ex-Vivo Applications Transplantation Pancreas Perfusion Multi-parametric MRI
Accepted
Alexander J Daniel 1, Mohamed Elzawahry2, Aaron Axford3, Damian Tyler3,4, Susan Francis1,5, James Hunter2
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom
2Nuffield Department of Surgical Science, University of Oxford, Oxford, United Kingdom
3Oxford Centre for Clinical MR Research (OCMR), University of Oxford, Oxford, United Kingdom
4Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
5NIHR Nottingham Biomedical Research Centre, Nottingham, United Kingdom
Presenting Author: Alexander J Daniel

Synopsis

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References

1. Dholakia S, Mittal S, Quiroga I, et al. Pancreas Transplantation: Past, Present, Future. Am J Med. 2016;129(7):667-673. doi:10.1016/j.amjmed.2016.02.011 [doi]
2. NHSBT. Organ and Tissue Donation and Transplantation Activity Report 2023/24. NHSBT; 2024. https://nhsbtdbe.blob.core.windows.net/umbraco-assets-corp/33778/activity-report-2023-2024.pdf.
3. Westerkamp AC, Karimian N, Matton APM, et al. Oxygenated Hypothermic Machine Perfusion After Static Cold Storage Improves Hepatobiliary Function of Extended Criteria Donor Livers. Transplantation. 2016;100(4):825. doi:10.1097/TP.0000000000001081 [doi]
4. Moers C, Smits JM, Maathuis MHJ, et al. Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation. N Engl J Med. 2009;360(1):7-19. doi:10.1056/NEJMoa0802289 [doi]
5. Mesnard B, Masset C, Ogbemudia E, et al. Is 2 h of Hypothermic Machine Perfusion for Pancreas Preservation Effective in Improving Graft Reperfusion? Transplant Direct. 2025;11(8):e1834. doi:10.1097/TXD.0000000000001834 [doi]
6. Quality in Organ Donation (QUOD). https://quod.org.uk/. Accessed October 23, 2025.
7. Daniel AJ, Fawaz S, Charles P, et al. Development of an MR Imaging Protocol for Ex-Vivo Assessment of Deceased Donor Human Kidneys. In: Proc. Intl. Soc. Mag. Reson. Med. 32. Toronto; 2023:3805. https://doi.org/10.58530/2023/3805 [doi]
8. Daniel AJ, Nery F, Sousa J, et al. UKRIN Kidney Analysis Toolbox (UKAT): A Framework for Harmonized Quantitative Renal MRI Analysis. In: Proc. Intl. Soc. Mag. Reson. Med. 30. Vol 29. Online; 2021:3765. https://cds.ismrm.org/protected/21MProceedings/PDFfiles/3765.html.
9. Daniel AJ, Nery F, Sousa J, Buchanan C. UKRIN Kidney Analysis Toolbox. October 2024. https://doi.org/10.5281/zenodo.14014598 [doi]
10. Andersson JLR, Skare S, Ashburner J. How to correct susceptibility distortions in spin-echo echo-planar images: application to diffusion tensor imaging. NeuroImage. 2003;20(2):870-888. doi:10.1016/S1053-8119(03)00336-7 [doi]
11. Smith SM, Jenkinson M, Woolrich MW, et al. Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage. 2004;23:S208-S219. doi:10.1016/j.neuroimage.2004.07.051 [doi]
12. Marc Lebel R. StimFit: A Toolbox for Robust T2 Mapping with Stimulated Echo Compensation. In: Proc. Intl. Soc. Mag. Reson. Med. 20. Melbourne; 2012:2558. https://archive.ismrm.org/2012/2558.html.
13. Li H, Daniel AJ, Buchanan CE, et al. Improvements in Between-Vendor MRI Harmonization of Renal T2 Mapping using Stimulated Echo Compensation. J Magn Reson Imaging. February 2024. doi:10.1002/jmri.29282 [doi]
14. Stikov N, Boudreau M, Levesque IR, Tardif CL, Barral JK, Pike GB. On the accuracy of T1 mapping: Searching for common ground. Magn Reson Med. 2015;73(2):514-522. doi:10.1002/mrm.25135 [doi]
15. Daniel AJ, Francis ST. Assessing the Impact of Imaging Parameters on MRI Measurement of Kidney T2. J Magn Reson Imaging. 2025. doi:10.1002/jmri.70127 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/669-04-002