Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
502-03-004 ISMRM Abstract

Multicenter normative neonatal brain growth trajectories identify early predictors of neurodevelopment in preterm infants

Primary: Pediatrics - Neonatal
Secondary: Neuro - Development
502-03-004 · Defining "Normal" in Pediatric Brain MRI · Wednesday, 13 May, 1:40 PM–3:30 PM · Hall 1B
Keywords: Brain chart Normative modeling Structural MRI Preterm infants Early brain development
Accepted
Joana Sa de Almeida 1,2,3,4, Gareth Ball3,5, Richard Beare3,6, Chris Adamson3, Lara Lordier1, Claire Kelly3,7, Peter Anderson4,7,8, Alicia Spittle4,9, Petra Hüppi1,2, Jeanie Cheong4,10,11, Deanne Thompson3,4,5,7
1Division of Development and Growth, University Hospitals of Geneva, Geneva, Switzerland, Switzerland
2ChildLab, Faculty of Medicine, University of Geneva, Geneva, Switzerland, Switzerland
3Developmental Imaging, Murdoch Children’s Research Institute, Melbourne, Australia, Australia
4Victorian Infant Brain Studies, Murdoch Children's Research Institute, Melbourne, Australia, Australia
5Department of Paediatrics, University of Melbourne, Melbourne, Australia, Australia
6Imaging and Bioinformatics, Peninsula Clinical School, School of Translational Medicine, Monash University, Australia
7Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia, Australia
8Department of Pediatrics, UC Irvine, Irvine, United States of America
9Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Australia
10Royal Women's Hospital, Melbourne, Victoria, Australia, Australia
11Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Australia, Australia
Presenting Author: Joana Sa de Almeida

Synopsis

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References

1. Marquand AF, Rezek I, Buitelaar J, Beckmann CF. Understanding Heterogeneity in Clinical Cohorts Using Normative Models: Beyond Case-Control Studies. Biol Psychiatry. 2016;80(7):552-561.
2. Bethlehem RAI, Seidlitz J, White SR, et al. Brain charts for the human lifespan. Nature. 2022;604(7906):525-533.
3. Dimitrova R, Arulkumaran S, Carney O, et al. Phenotyping the Preterm Brain: Characterizing Individual Deviations From Normative Volumetric Development in Two Large Infant Cohorts. Cereb Cortex. 2021;31(8):3665-3677.
4. Adamson CL, Alexander B, Ball G, et al. Parcellation of the neonatal cortex using Surface-based Melbourne Children's Regional Infant Brain atlases (M-CRIB-S). Sci Rep. 2020;10(1):4359.
5. Klein A, Tourville J. 101 labeled brain images and a consistent human cortical labeling protocol. Front Neurosci. 2012;6:171.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/502-03-004