Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
608-03-009 ISMRM Abstract

Resolving and Quantifying Subvoxel Tissue Components in Multidimensional MRI for Clinical Translation

Primary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
Secondary: Contrast Mechanisms - Relaxometry
608-03-009 · Quantitative Imaging: Multiparametric and Synthetic MRI · Thursday, 14 May, 4:00 PM–5:50 PM · Meeting Room 1.60
Keywords: Quantitative imaging biomarkers Brain tissue microstructure Blind source separation Tissue compartments Relaxation-Diffusion Spectroscopy
Accepted
Alexandru V Avram1,2, Kulam Najmudeen Magdoom1,2,3, Ella Wilczynski1,2, Peter J Basser1,2
1Section on Quantitative Imaging and Tissue Sciences (SQITS), Eunice Kennedy Shriver - National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, United States of America
2National Institutes of Health (NIH), Bethesda, United States of America
3Military Traumatic Brain Injury Initiative (MTBI2), The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, United States of America
Presenting Author: Nathan H Williamson

Synopsis

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References

1. Benjamini, D. & Basser, P. J. Magnetic resonance microdynamic imaging reveals distinct tissue microenvironments. NeuroImage 163, 183-196 (2017). https://doi.org/10.1016/j.neuroimage.2017.09.033 [doi]
2. Kim, D., Doyle, E. K., Wisnowski, J. L., Kim, J. H. & Haldar, J. P. Diffusion-relaxation correlation spectroscopic imaging: A multidimensional approach for probing microstructure. Magnetic Resonance in Medicine 78, 2236-2249 (2017). https://doi.org/https://doi.org/10.1002/mrm.26629 [doi]
3. Slator, P. J. et al. Data-Driven multi-Contrast spectral microstructure imaging with InSpect: INtegrated SPECTral component estimation and mapping. Medical Image Analysis 71, 102045 (2021). https://doi.org/https://doi.org/10.1016/j.media.2021.102045 [doi]
4. Avram, A. V., Sarlls, J. E. & Basser, P. J. Whole-Brain Imaging of Subvoxel T1-Diffusion Correlation Spectra in Human Subjects. Frontiers in Neuroscience 15 (2021). https://doi.org/10.3389/fnins.2021.671465 [doi]
5. Pas, K., Komlosh, M. E., Perl, D. P., Basser, P. J. & Benjamini, D. Retaining information from multidimensional correlation MRI using a spectral regions of interest generator. Scientific Reports 10, 1-10 (2020). https://doi.org/10.1038/s41598-020-60092-5 [doi]
6. Labadie, C. et al. Myelin water mapping by spatially regularized longitudinal relaxographic imaging at high magnetic fields. Magnetic resonance in medicine 71, 375-387 (2014). https://doi.org/10.1002/mrm.24670 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/608-03-009