631-02-014 / 631-02-014 ISMRM Abstract

Chemical Exchange Saturation Transfer (CEST) MRI for Non-invasive Molecular Imaging in Renal Transplant Recipients

Primary: Contrast Mechanisms - CEST / APT / NOE

Secondary: Body - Kidney

631-02-014 · Everything About Contrast Mechanism · Thursday, 14 May, 1:40 PM–3:16 PM · Roof Terrace

Keywords: CEST & MT CEST / APT / NOE CEST MRI Kidney MRI Kidney transplantation

Accepted

Valensia N Anthony ^1,2, Ding Xia^1,2, Mira M Liu^1,2, Ian Bolger^1,2, Samira Farouk³, Octavia Bane^1,2, Sara Lewis^1,2, Li Feng^4,5, Xiang Xu^1,2

¹BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, United States of America

²Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, United States of America

³Department of Transplant Nephrology, Icahn School of Medicine at Mount Sinai, New York, United States of America

⁴Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, United States of America

⁵Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, United States of America

Presenting Author: Valensia N Anthony

Synopsis

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References

1. Eikmans M, Gielis EM, Ledeganck KJ, Yang J, Abramowicz D, Claas FFJ. Non-invasive Biomarkers of Acute Rejection in Kidney Transplantation: Novel Targets and Strategies. Front Med (Lausanne). 2018;5:358. doi:10.3389/fmed.2018.00358 [doi]

2. Park S, Sellares J, Tinel C, Anglicheau D, Bestard O, Friedewald JJ. European Society of Organ Transplantation Consensus Statement on Testing for Non-Invasive Diagnosis of Kidney Allograft Rejection. Transpl Int. 2023;36:12115. doi:10.3389/ti.2023.12115 [doi]

3. van Zijl PC, Yadav NN. Chemical exchange saturation transfer (CEST): what is in a name and what isn't? Magn Reson Med. 2011;65(4):927-48. doi: 10.1002/mrm.22761. [doi]

4. Stabinska J, Keupp J, McMahon MT. CEST MRI for Monitoring Kidney Diseases. Advanced Clinical MRI of the Kidney2023. p. 345-60. doi: 10.1007/978-3-031-40169-5_22 [doi]

5. Xu X, Leforestier R, Xia D, Block KT, Feng L. MRI of GlycoNOE in the human liver using GraspNOE-Dixon. Magn Reson Med. 2025;93(2):507-18. doi: 10.1002/mrm.30270 [doi]

6. Feng L, Wen Q, Huang C, Tong A, Liu F, Chandarana H. GRASP-Pro: imProving GRASP DCE-MRI through self-calibrating subspace-modeling and contrast phase automation. Magn Reson Med. 2020;83(1):94-108. 2020;83:94-108. doi: 10.1002/mrm.27903 [doi]

7. Hua J, Jones CK, Blakeley J, Smith SA, van Zijl PC, Zhou J. Quantitative description of the asymmetry in magnetization transfer effects around the water resonance in the human brain. Magn Reson Med. 2007;58(4):786-93. doi:10.1002/mrm.21387 [doi]

8. Zaiss M, Schmitt B, Bachert P. Quantitative separation of CEST effect from magnetization transfer and spillover effects by Lorentzian-line-fit analysis of z-spectra. J Magn Reson. 2011;211(2):149-55. doi:10.1016/j.jmr.2011.05.001 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/631-02-014