Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
469-05-001 ISMRM Abstract

Impact of Skin Barrier Function on Skin Sodium Quantification with 23Na MRI at 7T

Primary: Contrast Mechanisms - Non-Proton
Secondary: Physics & Engineering - High-Field MRI
469-05-001 · Non-Proton MRI: Methods and Applications · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row J
Keywords: Skin Sodium Quantification Repeatability and reproducibility Skin Barrier Function Tape-strip Sodium (23Na) MRI
Accepted
Aditya Jhajharia 1,2, Jie Zhu2, Zanib Naeem1, Katrina Abuabara2, Michael Ohliger1, An T Vu1,3, Jeremy W Gordon1
1Department of Radiology and Biomedical Imaging, University Of California, San Francisco (UCSF), United States of America
2Department of Dermatology, University Of California, San Francisco (UCSF), United States of America
3Radiology Service, San Francisco Veteran Affairs Health Care System, San Francisco, United States of America
Presenting Author: Aditya Jhajharia

Synopsis

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References

1. Chattopadhyay A, Tully J, Shan J, et al. Sodium in the skin: a summary of the physiology and a scoping review of disease associations. Clin Exp Dermatol. 2023 Jul 7;48(7):733-743.
2. Hofmeister LH, Perisic S, Titze J. Tissue sodium storage: evidence for kidney-like extrarenal countercurrent systems? Pflugers Arch. 2015 Mar;467(3):551-8.
3. Elias PM. Skin barrier function. Curr Allergy Asthma Rep. 2008 Jul;8(4):299-305.
4. Kopp C, Linz P, Dahlmann A, et al. 23Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients. Hypertension. 2013 Mar;61(3):635-40.
5. Dyke JP, Meyring-Wösten A, Zhao Y, et al. Reliability and agreement of sodium (23Na) MRI in calf muscle and skin of healthy subjects from the US. Clin Imaging. 2018 Nov-Dec;52:100-105.
6. Christensen NV, Vaeggemose M, Bøgh N, et al. A user independent denoising method for x-nuclei MRI and MRS. Magn Reson Med. 2023 Dec;90(6):2539-2556.
7. Reed JT, Ghadially R, Elias PM. Skin type, but neither race nor gender, influence epidermal permeability barrier function. Arch Dermatol. 1995 Oct;131(10):1134-8.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/469-05-001