468-02-007 ISMRM Abstract

Effects of Aging and Type 2 Diabetes on Neurovascular Coupling to Visual Stimulation

Primary: Brain Function and fMRI - Task/Intervention Based fMRI

Secondary: Neuro - Aging

468-02-007 · Type 2 Diabetes · Tuesday, 12 May, 9:15 AM–10:10 AM · Digital Posters Row I

Keywords: Diabetes fMRI (task based) Aging Neurovascular coupling

Accepted

Yakun Zhang¹, Shichun Chen¹, Kyle Sporn², Daniel Y Tso³, Weiying Dai ¹

¹School of Computing, The State University of New York at Binghamton, Binghamton, United States of America

²Norton College of Medicine, State University of New York Upstate Medical University, Syracuse, United States of America

³Department of Neuroscience and Ophthalmology, State University of New York Upstate Medical University, Syracuse, United States of America

Presenting Author: Weiying Dai

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References

1. Phillips, A. A., Chan, F. H., Zheng, M. M., Krassioukov, A. V. & Ainslie, P. N. Neurovascular coupling in humans: Physiology, methodological advances and clinical implications. J Cereb Blood Flow Metab 36, 647-664, doi:10.1177/0271678X15617954 (2016). [doi]

2. Barloese, M. C. J., Bauer, C., Petersen, E. T., Hansen, C. S., Madsbad, S. & Siebner, H. R. Neurovascular Coupling in Type 2 Diabetes With Cognitive Decline. A Narrative Review of Neuroimaging Findings and Their Pathophysiological Implications. Front Endocrinol (Lausanne) 13, 874007, doi:10.3389/fendo.2022.874007 (2022). [doi]

3. Luo, S., Xia, L., Wang, Y., Tang, Y., Dong, J., Liu, R. & Feng, L. Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions. Transl Vis Sci Technol 14, 10, doi:10.1167/tvst.14.3.10 (2025). [doi]

4. Fazeli, P. K., Lee, H. & Steinhauser, M. L. Aging Is a Powerful Risk Factor for Type 2 Diabetes Mellitus Independent of Body Mass Index. Gerontology 66, 209-210, doi:10.1159/000501745 (2020). [doi]

5. West, K. L., Zuppichini, M. D., Turner, M. P., Sivakolundu, D. K., Zhao, Y., Abdelkarim, D., Spence, J. S. & Rypma, B. BOLD hemodynamic response function changes significantly with healthy aging. Neuroimage 188, 198-207, doi:10.1016/j.neuroimage.2018.12.012 (2019). [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/468-02-007