Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-02-011 ISMRM Abstract

NODDI, Diffusion Tensor Microstructural Abnormalities and Gray Matter Atrophy Contribute to Cognitive Impairment in RRMS

Accepted
Zhuo Wang1, Jing Zhang 2, Kai AI3
1Department of Magnetic Resonance, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
2The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
3Department of Clinical and Technical Support, Philips Healthcare (Xi'an), Xi'an, China
Presenting Author: Jing Zhang

Synopsis

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References

1. 1、Rocca MA, Amato MP, De Stefano N, Enzinger C, Geurts JJ, Penner IK et al (2015) Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis. Lancet Neurol 14(3):302-317.
2. 2、Grussu F, Schneider T, Tur C, Yates RL, Tachrount M, Ianus A et al (2017) Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology? Ann Clin Transl Neurol 4(9):663–679.
3. 3、Collorone S, Cawley N, Grussu F, Prados F, Tona F, Calvi A et al (2020) Reduced neurite density in the brain and cervical spinal cord in relapsing-remitting multiple sclerosis: A NODDI study. Mult Scler 26(13):1647–1657.
4. 4、Amato, M.P., Morra, V.B., Falautano, M., Ghezzi, A., Goretti, B., Patti, F., Riccardi, A., Mattioli, F., 2018. Cognitive assessment in multiple sclerosis-an Italian consensus. Neurol Sci 39, 1317-1324.
5. 5、Zhang H, Schneider T, Wheeler-Kingshott CA, Alexander DC (2012) NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. Neuroimage 61(4):1000–1016.

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