Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Oral

AI-Enabled Image Synthesis and Translation

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AI-Enabled Image Synthesis and Translation
Oral
Analysis Methods
Tuesday, 12 May 2026
Auditorium 1
13:40 - 15:30
Moderators: Emmanuel BARBIER & Yannik Ott
Session Number: 403-02
No CME/CE Credit
Techniques and processes designed to create images with contrasts not directly acquired from a limited data set.
Skill Level: Intermediate

13:40   403-02-001.  Introduction
Emmanuel BARBIER
Grenoble Institut Neurosciences, Grenoble, France
13:51 Figure 403-02-002.  Analysis of the Information Contribution of Different Contrast Scans in an MRI Examination aided by Content/style Modeling
Summa Cum Laude AMPC Selected
Chinmay Rao, Matthias van Osch, Mariya Doneva, Jakob Meineke, Elwin de Weerdt, Laurens Beljaards, Marius Staring
Leiden University Medical Center, Leiden, Netherlands
Impact: Quantification of the information contribution of scans in an MRI exam can assist the operator/radiologist in optimizing exam protocols for high efficiency with minimum information loss. Such optimized exams could reduce strain on the patient, while increasing the hospital’s patient-throughput.
14:02 Figure 403-02-003.  Generalization of Synthetic CT from Diagnostic Spine MRI: A Multi-Center Approach
Summa Cum Laude
Ryan Pollitt, Tom P. Schlösser, Lambertus Bartels, Marijn van Stralen, Peter Seevinck
University Medical Center Utrecht, Utrecht, Netherlands
Impact: We used a multi-center paired spinal MR/CT dataset to create an MR-to-CT network, generalizing to three out-of-distribution centers. Our findings facilitate radiation-free 3D bone visualization without changes to existing diagnostic scan protocols, unlocking its potential for surgical applications.
14:13 Figure 403-02-004.  Synthesising Quantitative Susceptibility Maps from Multi-Parametric Maps (MPM2QSM)
Magna Cum Laude
Mitchel Lee, Fenella Kirkham, Karin Shmueli
University College London, London, United Kingdom
Impact: We show that quantitative susceptibility maps can be reconstructed from standard multi-parametric MRI data without phase information. It demonstrates a new way to recover otherwise lost tissue information, potentially enabling retrospective analysis of existing imaging datasets.
14:24 Figure 403-02-005.  Contrast Synthesis Network Guided by Scan Parameters
Magna Cum Laude
Jaehyeon Koo, Minjun Kim, Taechang Kim, Rokgi Hong, Jiye Kim, Hwihun Jeong, Jongho Lee
Seoul National University, Seoul, Korea, Republic of
Impact: The proposed network enables MR image translation (T1w⟷T2w) based on metadata (image contrast and scan parameters). By synthesizing parameter-specified contrasts from limited acquisitions, this approach can reduce scan burden while offering flexibility in image contrast determined by target scan parameters.
14:35 Figure 403-02-006.  Graph-Attention Fusion with Retrieval Prompt Learning for Brain MRI Synthesis
Ning Jiang, Zhengyong Huang, Yao Sui
Peking University, Beijing, China
Impact: We developed a graph-attention fusion framework for high-quality synthesis of brain MRI images. This approach delivers superior synthesis quality in motion artifact removal and cross-modal translation, highlighting its potential to enhance neuroimaging analysis when high-quality or comprehensive data are lacking.
14:46 Figure 403-02-007.  Multiscale Subtraction Consistency-based Generative Adversarial Networks for Contrast-Agent-Free Breast DCE-MRI Synthesis
Zhikai Yang, Cristina Zhang, Muzhen He, Rodrigo Moreno
KTH Royal Institute of Technology, Stockholm, Sweden
Impact: This study enables contrast-free, multi-phase breast DCE-MRI generation using non-contrast inputs, reducing GBCA dependence and patient risk while preserving diagnostic fidelity, paving the way for safer, faster, and more accessible breast cancer imaging and future AI-driven contrast synthesis research.
14:57 Figure 403-02-008.  Synthetic Contrast-Enhanced T1 MRI from Non-Contrast MRI Using Pix2pix GAN for Endometrial Cancer: A Multicenter Study
Wenyi Yue, Haijie Wang, Mingxiang Wei, Xiaoyun Liang, Qi Yang
Beijing Chaoyang Hospital, Capital Medical University, beijing, China
Impact: This study demonstrates the feasibility of generating synthetic T1CE images from non-contrast MRI, thus reducing reliance on contrast agents and improving clinical workflows. This approach provides a non-contrast alternative to endometrial cancer detection and diagnosis.
15:08 Figure 403-02-009.  Integrating DCE-MRI and Synthetic MRI Reveals Pathophysiological Subtypes of Synovitis in Knee Osteoarthritis
Meng Zhang, Weiyin Vivian Liu, Yong Zhu, Luanning Li, Xiaokang Wang, Xuying Chen
Xiangyang Hospital of Traditional Chinese Medicine [Xiangyang Institute of Traditional Chinese Medicine], XiangYang, China
Impact: This research transforms synovitis management by establishing pathophysiologically distinct subtypes through integrated MRI. This refined stratification enables precise treatment matching—directing anti-angiogenic therapy to hypervascular subtypes while avoiding overtreatment in fibrotic cases—optimizing therapeutic efficacy and accelerating clinical trials for targeted therapies.
15:19   403-02-010.  Guided Discussion
Yannik Ott
King's College London, London, United Kingdom

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