Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Oral

New Developments in Breast MRI

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New Developments in Breast MRI
Oral
Body
Wednesday, 13 May 2026
Hall 1B
16:00 - 17:50
Moderators: Valeria Romeo & Mami Iima
Session Number: 502-04
CME/CE Credit Available
This session highlights impactful innovations in breast MRI in the field of lesions classification, response to therapy and outcome prediction
Skill Level: Intermediate

16:00 Figure 502-04-001.  Shape Descriptors of Fibroglandular Tissue on Breast MRI and their Association with Background Parenchymal Enhancement
Henry Rusinek, Artem Mikheev, Gene Kim, Samantha Heller
NYU Grossman School of Medicine, New York, United States of America
Impact: This pilot study shows that quantitative shape descriptors of fibroglandular tissue predict background parenchymal enhancement. Results suggest that breast tissue morphology may potentially serve as an imaging biomarker, complementing density and enhancement measures.
16:11 Figure 502-04-002.  Multiparametric MRI-Based Nomogram for Predicting MVD in Breast Carcinoma
Zhengtong Wang, Weiwei Wang, Zhanguo Sun, Xiuzheng Yue
Impact: IVIM and DKI parameters, especially f, can noninvasively assess MVD. A combined nomogram model aids precision breast cancer care.
16:22 Figure 502-04-003.  Decoding Breast Cancer Microstructure with Time-Dependent Diffusion MRI: Toward In Vivo Histology Assessment
Yu Zhou, Suyu Liu, Wenbo Sun, Hao Mei, Xiaohui Chen, Jinfeng Lv, Xuan Li, Wei Chen, Thorsten Feiweier, Ming Deng, Liying Xu
Zhongnan Hospital of Wuhan University, Wuhan, China
Impact: Time-dependent diffusion MRI allows noninvasive assessment of breast cancer microstructure, improving diagnostic accuracy in lesion characterization and showing strong correlations with molecular subtypes and proliferative activity. It holds significant potential for clinical use in precision oncology.
16:33 Figure 502-04-004.  Integrative Synthetic, Diffusion, and Perfusion MRI for Noninvasive Prediction of Breast Cancer Immunohistochemical Markers
Lihua Xiang, Jie Shi, Ling Yang, Guangzheng Li
The First Affiliated Hospital of Soochow University, Suzhou, China
Impact: Multiparametric MRI integrating SyMRI, DISCO, and DWI enables noninvasive assessment of key breast cancer immunohistochemical markers, bridging microstructural, diffusion, and perfusion information to support personalized treatment planning and potentially reduce biopsy dependence.
16:44 Figure 502-04-005.  Early Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer with Magnetic Resonance Fingerprinting
Holly Marshall, Ananya Panda, Yilun Sun, Armanda Amin, Bahar Moftakhar, Nicole Seiberlich, Donna Plecha, Vikas Gulani, Mark Griswold, Chris Flask, Yong Chen
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States of America
Impact: The findings in this study suggest that breast Magnetic Resonance Fingerprinting has the potential for early assessment of response to neoadjuvant chemotherapy in breast cancer treatment and to guide treatment modifications to improve patient outcomes.
16:55 Figure 502-04-006.  Advanced Diffusion-Weighted Imaging Markers for Prediction of Breast Cancer Treatment Response in a Multisite Trial
Summa Cum Laude AMPC Selected
Debosmita Biswas, Chen Shen, Dariya Malyarenko, Patrick Bolan, Stephane Loubrie, Isabella Li, Anum Kazerouni, Brendon Moloney, Xin Li, Dallas Turley, Marissa Lawson, Rebecca Rakow-Penner, Jennifer Specht, Suzanne Dintzis, Habib Rahbar, Thomas Chenevert, James Holmes, Wei Huang, Savannah Partridge
University of Washington, Seattle, United States of America
Impact: Diffusion-weighted imaging markers demonstrate accurate early prediction of pathologic response in breast tumors treated with neoadjuvant chemotherapy, outperforming RECIST. Results support their potential as imaging biomarkers to help optimize breast cancer treatments in the future.
17:06 Figure 502-04-007.  Prediction of Sentinel Lymph Node Metastasis in Breast Cancer Using Intratumoral T2 Mapping and Peritumoral Edema
Tianwen Xie, Yan Huang, Caixia Fu, Tom Hilbert, Tobias Kober, Weijun Peng, Yajia Gu
Fudan University Shanghai Cancer Center, Shanghai, China
Impact: Peritumoral edema identified on multi-echo sequence may serve as a noninvasive biomarker to stratify sentinel lymph node metastasis risk in clinically node-negative breast cancer, which may omit SLN biopsy. Further validation of T2 mapping in larger radiomic studies is warranted.
17:17 Figure 502-04-008.  Association of background parenchymal enhancement suppression during neoadjuvant chemotherapy with breast cancer survival
Natsuko Onishi, Wen Li, Matthew Gibbons, Lisa Wilmes, Pouya Metanat, Teffany Joy Bareng, Bonnie Joe, John Kornak, Christina Yau, I-SPY 2 Investigator Network, I-SPY2 Imaging Working Group, Laura Esserman, Nola Hylton
Impact: Background parenchymal enhancement (BPE) on breast MRI may serve as an early prognostic biomarker for hormone receptor-positive breast cancer, as lack of BPE suppression early in the course of neoadjuvant chemotherapy is associated with lower distant recurrence-free survival after treatment.
17:28   502-04-009.  Guided Discussion
Valeria Romeo
Università degli Studi di Napoli Federico II, Naples, Italy

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