Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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470-03-088.
FixelBayes: A Bayesian framework for fixel-based analysis of diffusion MRI data
Impact: FixelBayes allows researchers to distinguish
between inconclusive results and true null effects in diffusion MRI, enabling
identification of subtle white matter differences that may inform future
studies and improve the interpretation of small-effect cohorts.
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470-03-089.
GenTract - Generative Models for Global Tractography
Impact: We introduce GenTract, the first global generative tractography framework. By generating complete streamlines informed by the brain’s global anatomy, it avoids the cumulative errors of local methods, enabling more robust white-matter tractography for clinical applications, such as neurosurgical planning.
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470-03-090.
A Dual-Stream Fusion Framework for Tractography Fiber Classification with Joint dMRI and fMRI data
Impact: We introduce a tractography parcellation method that moves beyond traditional, geometry-based approaches by integrating dMRI-fMRI data. A dual-stream fusion strategy is proposed to enable highly accurate, functionally relevant tract parcellation, benefiting neuroscience and clinical assessment of complex fiber pathways.
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470-03-091.
Automated DRTT tractography reproducibility: impact of session, and labeling approach
Impact: This work demonstrates that results
of automated DRTT tractography were
reproducible between 3 different scan sessions and
showed only minimal dependence on parcellation variability. These results support
the clinical integration of diffusion-based targeting for the VIM in functional neurosurgery.
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470-03-092.
Advanced tractography pipeline for neonatal connectomics: effect of post-processing techniques
Impact: By
applying advanced diffusion MRI processing and tractography methods to neonatal
data, this work explores their potential to enhance connectome reconstruction
and evaluates how methodological choices influence global network measures in the
developing
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470-03-093.
Co-localized Microstructural and Metabolite Tractometry of the Upper Corticospinal Tract in Normal Healthy Brain
Impact: Multiparametric normative CST tract profiles integrating metabolic and
microstructural measures could enable early detection of white matter
abnormalities in ALS and similar neurodegenerative disorders involving the
upper motor neurons, supporting development of region-specific biomarkers and
guiding future therapeutic strategies.
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470-03-094.
Diffusion MRI Tract profiling of Bundle geometry
Impact: We propose Bundle Geometry Profiles (BGP) to quantify global white-matter tract geometry from diffusion MRI tractography, enabling precise characterization of bundle shape and structure and facilitating identification of geometric biomarkers underlying brain organization and neurobehavioral changes.
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470-03-095.
Improving tractography reconstructions with asymmetric FOD tractography: preliminary evidence on the cortico-spinal tract
Impact: In this study we evaluate asymmetric FOD tractography, providing preliminary evidence for improved white matter reconstruction. CST reconstructions demonstrate increased tract volume with improved lateral branching, indicating that aFODs can better represent complex bending and fanning configurations than symmetric FODs.
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470-03-096.
Validating Automatic Arcuate Fasciculus Segmentation in Routine Clinical Data for Neurosurgery Planning
Impact: This reproducible and scalable automation pipeline facilitates reliable arcuate fasciculus reconstruction, enabling broader clinical application in neurosurgical planning and language lateralization analysis.
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