Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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466-01-001.
MRI-Based Risk Stratification of Immunotherapy Response in Locally Advanced Rectal Cancer: A Pilot Study
Impact: This study introduces a
simple and clinically applicable MRI-based system that stratifies rectal cancer
patients by immunotherapy benefit, enabling precision oncology through imaging
biomarkers and promoting efficient use of immune checkpoint inhibitors in
neoadjuvant treatment strategies.
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466-01-002.
Application of synthetic MRI to evaluate rectal cancer grading and PIK3CA mutation status
Impact: This study demonstrates that synthetic MRI enables noninvasive preoperative assessment of histological grade and PIK3CA mutation in rectal cancer. The findings may facilitate precise molecular stratification, guide personalized treatment, and inspire further research on quantitative imaging biomarkers for tumor heterogeneity.
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466-01-003.
MRI-driven Deep Learning for Predicting Pathologic Complete Response After Neoadjuvant Chemoradiotherapy in Rectal Cancer
Impact: An interpretable deep learning radiomics model derived from pre-nCRT multiparametric MRI enables accurate, noninvasive prediction of pathological complete response in locally advanced rectal cancer, offering a robust imaging biomarker to support individualized, organ-preserving treatment strategies in clinical decision-making.
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466-01-004.
QSM-Based Habitat Analysis Provides a Novel Approach for Identifying Hypoxia in Rectal Cancer:A Preliminary Prospective Study
Impact: QSM-MRI can be used to identify the hypoxic state of
rectal cancer non-invasively. QSMhabitat is more effective than QSMmean
and DCEKtrans at identifying severe hypoxic RCs, which may
facilitate more precise, personalized treatment plans.
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466-01-005.
Prediction of Rectal Cancer Microsatellite Instability by Integrating MR Radiomics, Habitat Analysis, and Genomics
Impact: This study provides a highly accurate,
non-invasive predictive tool. Crucially, it offers, for the first time, a
genomic-level explanation for the biological mechanisms underlying the imaging
model, significantly enhancing its credibility and potential for clinical
translation.
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466-01-006.
Preoperative DCE-MRI Tumor Habitat Features Improve Postoperative Prognostic Stratification in Stage II–III Rectal Cancer
Impact: By combining preoperative DCE-MRI habitat features with routine clinical factors, we can flag stage II–III rectal cancer patients at high risk of postoperative recurrence, enabling intensified surveillance or escalation of adjuvant therapy beyond what TNM staging alone would suggest.
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466-01-007.
Whole-Tumor IVIM-DWI Histogram Model for Preoperative Diagnosis of Tumor Deposits in Rectal Cancer
Impact: Whole-tumor IVIM-DWI histogram analysis captures intratumoral diffusion and perfusion heterogeneity, enabling accurate preoperative identification of tumor deposits. This technique offers a potential imaging biomarker for individualized treatment planning and risk stratification in rectal cancer.
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466-01-008.
A Clinical-Radiomics Nomogram from Multiparametric MRI for Personalized Risk Stratification in Resectable Rectal Cancer
Impact: This
robust, preoperative clinical-radiomics model offers a superior, data-driven
tool for predicting disease-free survival, potentially enabling more
personalized and effective adjuvant therapy planning for patients with
resectable rectal cancer.
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466-01-009.
Deep learning radiomics-based prediction model for lymph node metastasis after neoadjuvant chemoradiotherapy in locally advan
Impact: Accurate evaluation of lymph node metastasis (LNM)
after neoadjuvant chemoradiotherapy (nCRT) remains a major challenge in locally
advanced rectal cancer (LARC).
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466-01-010.
Histogram Analysis of DKI for T Restaging and Predicting pCR of LARC Following Following Neoadjuvant Immunotherapy
Impact: DKI-derived histogram parameters may indeed be a powerful non-invasive imaging technique for the selection of local excision candidates (ypT0-1) and predicting pathological complete response in locally advanced rectal cancer following neoadjuvant immunotherapy.
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466-01-011.
MRI in Clinical Practice: Diagnosis of Regional Lymph Node Involvement in Rectal Cancer Using the Node-RADS
Impact: In terms of accuracy for assessing lymph node involvement in rectal cancer , MRI-based Node-RADS 1.0 performs better than the current ESGAR Criteria, while contrast-enhanced MRI outperforms contrast-enhanced CT due to its superior ability to characterize lymph node texture.
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466-01-012.
Dynamic Evaluation of Tumor Microenvironment during Anti-angiogenic Therapy in Colorectal Cancer using Multi-parametric MRI
Impact: This
study demonstrates that multi-parametric MRI can reliably evaluate tumor
microenvironment alterations during anti-angiogenic therapy. It provides a
noninvasive biomarker for monitoring treatment efficacy and optimizing
therapeutic strategies in colorectal cancer.
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466-01-013.
Segmenting Rectal Cancer from Multi-Sequence MR Images that Were Inconsistently Labelled
Impact: Our framework offers a strategy to mitigate annotation
uncertainty in rectal cancer segmentation model development. By utilizing
low-consensus cases as unlabeled data through semi-supervised learning, we may
be able to reduce dependency on extensive high-quality annotations while
preserving data scale.
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© 2026 International Society for Magnetic Resonance in Medicine