Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition - Mesoscale Functional MRI and Acquisition Strategies

Mesoscale Functional MRI and Acquisition Strategies

Digital Poster

Brain Function & fMRI

Wednesday, 13 May 2026

Digital Posters Row F

13:40 - 14:35

Session Number: 565-03

No CME/CE Credit

Similar Sessions

high-resolution fMRI of layers and columns and other small structures in the brain

		565-03-001. 3D EPI Enables Population Receptive Field Mapping with Ultra-High Spatiotemporal Resolution Dominik Zuschlag, David Linhardt, Rüdiger Stirnberg, Christian Windischberger Medical University of Vienna, Vienna, Austria Impact: We optimized a 3D-EPI protocol (0.7 mm isotropic, TR/TE=2000/25 ms, 64 slices) for high-resolution fMRI of the occipital cortex at 7T. This optimised protocol yields robust, high-quality retinotopic maps with appropriate coverage for layer-specific pRF mapping.
		565-03-002. Hierarchical processing of Chinese character in ventral temporal cortex: a laminar fMRI study at 7 Tesla Chen Liu, Siying Li, Jing An, Sisi Li, Xiaoqun Wang, Peng Zhang Chinese Academy of Sciences, Beijing, China Impact: Mesoscale evidence across cortical depth reveals the hierarchical processing of Chinese characters, demonstrating laminar fMRI as a powerful tool for investigating the neural circuitry of language processing in high-level cortex.
		565-03-003. BrainMLSR: An Energy Function-based Framework for Multi-Signal-Layer Cortical Surface Reconstruction from 5.0T MRI Shui Cao, Lu Shi, Lin Teng, Zifeng Lian, jiameng liu, Kaicong Sun, Feng Shi, Xiangshui Meng, Dinggang Shen School of Biomedical Engineering, ShanghaiTech University, Shanghai, China Impact: We present a novel energy function-based framework, called BrainMLSR, for reconstructing brain multi-signal-layer cortical surfaces. BrainMLSR accurately delineates cortical laminar structures from 5.0T T2-weighted FLAIR MRI, enabling precise quantitative analysis of layer-specific cortical morphology.
		565-03-004. Establishing the path to concurrent EEG-VASO acquisition at 7T. Daniel Marsh, Agatha Lenartowicz, Karen Mullinger, Susan Francis Sir Peter Mansfield Imaging Center, University of Nottingham, Nottingham, United Kingdom Impact: We demonstrate the feasibility of collecting EEG-VASO data at 7T to investigate the correlation of electrophysiology signals with CBV, allowing the study of response changes across layers whilst overcoming the challenges of draining veins effects dominant in GE-BOLD.
		565-03-005. Precise Interhemispheric Phase Mapping of Evoked Hemodynamics via Space–Frequency SVD Xiaochen Liu, David Hike, Jacob Duckworth, David Kleinfeld, Xin Yu Massachusetts General Hospital and Harvard Medical School, Boston, United States of America Impact: We validated space–frequency SVD as a precise tool for quantifying phase offsets in hemodynamic activity. It accurately recovered a 5s interhemispheric delay and revealed additional sub-second phase shifts, indicating layered signal propagation likely shaped by neurovascular coupling and circuit dynamics.
		565-03-006. Depth-dependent profiles of mesoscale color domains in macaque V2 and V4 revealed by 7T fMRI Yuqi Feng, Hongxing Sun, An Ping, Tian Feiyan, Xiao Du, Anna Roe, Jianbao Wang Zhejiang University, Hangzhou, China Impact: This study maps depth-dependent profiles of individual color domains using 7T fMRI and reveals distinct patterns between V2 and V4, providing new insights into laminar specificity and mesoscale organization of color information in the visual cortex.
		565-03-007. Mapping BOLD and CBV fMRI at the 100 µm isotropic resolution with the 14T Scanner Yuanyuan Jiang, David Hike, Nivetha Pasupathy, Xiaochen Liu, Xiaoqing Zhou, Alan Jasanoff, Xin Yu Massachusetts General Hospital and Harvard Medical School, Boston, United States of America Impact: Resolving the 3D vessel-specific fMRI signals will differentiate the neurovascular coupling-driven hemodynamic responses from vasodynamic propagation across the cerebrovascular network, enabling identification of novel imaging vascular biomarkers.
		565-03-008. Absence of Evidence or Evidence of Absence? How B1+ Inhomogeneity Degrades Interpretability of fMRI at Ultra-High Field Dana Ramadan, Susanne Stoll, Felix Glang, Pablo Grassi, Sebastian Mueller, Klaus Scheffler, Jonas Bause Max Planck Institute for Biological Cybernetics, Tübingen, Germany Impact: As we exemplarily show, submillimeter fMRI at ultra-high fields can be compromised by transmit-field inhomogeneity, particularly when the number of samples and/or the functional contrast are low. Thus, we recommend reporting transmit field maps alongside activation data for improved interpretation.
		565-03-009. PNS Optimized Pulses of EPI (POPE): simple adjustment to gradient pulse shape for practical high-resolution fMRI Renzo Huber, Dominik Rattenbacher, Rüdiger Stirnberg, Kenny (Chung) Kan, Alessandra Pizzuti, Omer Faruk Gulban, Florian Kroh, Bastien Guerin, Azma Mareyam, Susie Huang, Kyle Droppa, Cole Analoro, Chiara Mauri, Berkin Bilgic, Paul wighton, Lawrence Wald Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America Impact: While gradients are getting more powerful, PNS becomes increasingly relevant for high-resolution EPI. Here, we propose a simple modification of EPI pulse shapes that reduce slew rates exclusively at peak times. This allows us to achieve robust 0.3mm fMRI.
		565-03-010. Advancing Whole-Brain Ultra-High-Resolution fMRI at 7T Using Recurrent Inference Machines Mitra Tavakkoli, Filipe Ledo, Chaoping Zhang, Matthan Caan, Ravi Menon Robarts Research Institute - Western University, Canada Impact: This work could overcome current acceleration limits in spiral fMRI at 7T,enabling fast and accurate reconstruction of highly undersampled data. It will pave the way for whole-brain ultra-high-resolution fMRI with improved fine-scale neural detection while maintaining clinically feasible scan durations.
		565-03-011. Beyond Field Strength: The Impact of Gradient System Performance in 1.5T, 3T and 7T Functional and Diffusion Weighted Imaging Christoph Aigner, Nils Bodammer, Luke Edwards, Thomas Feg, Francisco Fritz, Dimo Ivanov, Simone Kühn, Sean Lee, Toralf Mildner, Andre Pampel, davide santoro, Sebastian Schröder, Robert Trampel, Desmond Tse, Nikolaus Weiskopf, Harald Möller, Siawoosh Mohammadi Max Planck Institute for Human Development, Berlin, Germany Impact: This multi-center, multi-system phantom and in-vivo study provides a critical technical benchmark for functional/structural MRI: 1.5T is resolution-limited, 3T achieves the best temporal stability, and 7T is B₀/B₁⁺ limited. These results will guide the optimal design of future neuroscience studies.
		565-03-012. Cortical orientation and layer dependence of bSSFP profile asymmetries in gray matter at 9.4 T Florian Birk, Dana Ramadan, Ali Aghaeifar, Klaus Scheffler, Rahel Heule Max Planck Institute for Biological Cybernetics, Tübingen, Germany Impact: The bSSFP asymmetry index in cortical gray matter varies with cortical depth and orientation. In vivo and Monte Carlo data imply a dependence on vascular susceptibility and blood volume fraction, with highest asymmetry occurring for vessels oriented parallel to B₀.
		565-03-013. Reducing MR-ARFI Scan Time Using a Physiological Noise-Free Reference Image and Polynomial Fitting for Noise Removal Shota Hodono, David Norris Radboud University, Nijmegen, Netherlands Impact: Using small number of b=0$s/mm^2$ volumes as reference, ARFI total scan time can be x4 accelerated. With polynomial fitting, physiological noise can be further suppressed, and even more acceleration can be achieved.
		565-03-014. Quantitative T1 imaging of the human brain at 11.7 Tesla using a MP2RAGE sequence with dynamic pTx and FatNav Aurélien Massire, Franck Mauconduit, Vincent Gras, Natalia Dudysheva, Joseph Brégeat, Son Chu, Shajan Gunamony, Daniel Gallichan, Alexandre Vignaud, Nicolas Boulant CEA NeuroSpin, Paris-Saclay University, CNRS BAOBAB, Gif-sur-Yvette, France Impact: The first 3D T₁-weighted brain anatomical images acquired in vivo at 11.7 Tesla are presented to the ultra-high field MR community, providing a central feature to pave the way for more advanced MRI explorations.
		565-03-015. Altered vascular network and resting-state fMRI functional connectivity in hypoperfusion mice Sangcheon Choi, Hidehiro Ishikawa, Zeping Xie, Bei Zhang, Xiaochen Liu, David Hike, Ken Arai, Xin Yu Massachusetts General Hospital and Harvard Medical School, Boston, United States of America Impact: This multi-modal resting-state fMRI framework enables detection of vascular and functional alterations following BCAS, providing a powerful tool to link cerebrovascular impairment with resting-state network disruption and advancing preclinical investigation of vascular contributions to brain functional connectivity.