Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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461-06-001.
Simultaneous gas-free calibrated fMRI and fNIRS measurements in human visual cortex: a feasibility study
Impact: The combined gas-free calibrated fMRI and fNIRS approach enhances the
physiological interpretability of metabolic mapping, providing a validated
basis for multimodal fusion models and future studies of altered neurovascular
coupling in patient populations.
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461-06-002.
Functional MRI compatible simultaneous cortical wide-field fluorescent Ca2+ and intrinsic oxy/deoxy-hemoglobin imaging
Impact: Simultaneous wide-field Ca2+ and fMRI provides two complementary measures of spontaneous brain activity across the mouse cortex. Yet, bridging these measures has proven challenging. The addition of oxy/deoxy-hemoglobin imaging stands to better our understanding of neurovascular coupling within brain networks.
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461-06-003.
Simultaneous BOLD and ASL-based cerebrovascular reactivity mapping and their relationship with baseline cerebral blood flow
Impact: Our work shows that BOLD-based CVR is confounded by baseline cerebral blood volume and cerebral blood flow, in contrast to Arterial Spin Labelling, hence this should be used to obtain a more reliable estimation of CVR.
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461-06-004.
Functional PET-MRI reveals flow-metabolism uncoupling and altered aerobic glycolysis in default network during working memory
Impact: These findings reveal complex physiological dynamics of the default-mode network under cognitive load, offering insight into disrupted DMN deactivations in mental illness and underscoring the need to revisit assumptions about brain physiology underlying fMRI deactivation.
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461-06-005.
Functional Electrical Properties Tomography with Simultaneous BOLD fMRI – Null Results with a Visual Task Using GLM and ICA
Impact: We showed that visual task-based fEPT gave null results similar to those from a task-free reference acquisition and inconsistent with simultaneous BOLD-fMRI. This first ICA of task-based fEPT shows that caution is needed with biophysical interpretation of fEPT results.
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461-06-006.
Multi-echo ASL-BOLD fMRI reveals attenuated inhibitory-control activation following mental fatigue
Impact: Multi-echo ASL-BOLD fMRI enables detection of neural alterations in inhibitory control following mental fatigue, advancing understanding of its impact on cognitive efficiency and providing an approach to assess fatigue-related performance decline.
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461-06-007.
High-resolution mapping of TMS-induced BOLD responses to motor cortex stimulation across the whole brain using the RF Cap.
Impact: We present full brain concurrent TMS/fMRI over motor cortex using a dedicated wearable 26-channel head RF coil array, the RF Cap. Results show high temporal
and spatial resolution of TMS effects, even at subthreshold stimulation
intensities with no muscle activation.
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461-06-008.
Evaluating the Sensitivity Limit of 3 T Spin-Lock fMRI for Detecting Alpha Oscillations in the Human Brain
Impact: Spin-Lock fMRI has the potential for direct mapping of oscillatory neuronal activity, yet the in vivo sensitivity remains a challenge. This study shows a practical sensitivity limit of 1.5 nT, based on noise level differences in spin-lock and BOLD acquisitions.
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461-06-009.
Feasibility of a wearable, inductively-coupled 7-channel RF receive array for concurrent 3T TMS/fMRI
Impact: We show a flexible, form-fitting,
low-cost “RF-Light” receive array for concurrent TMS-MRI scans. The RF-Light is inductively-coupled to remotely-positioned
vendor receive array coils, opening up space close to the head and providing
full freedom for TMS coil positioning.
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461-06-010.
Hippocampal connectivity in schizophrenia: a comparison of DASL and BOLD fMRI
Impact: Dynamic ASL
(DASL) is more sensitive than BOLD in detecting alterations of hippocampal resting
state functional connectivity in schizophrenia. If replicated, these
findings could provide new leads into hippocampal dysfunction in schizophrenia, suggesting that
DASL adds value for clinical neuroimaging.
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461-06-011.
Simultaneous two-voxel fMRS and fMRI of the motor cortex at 7T
Impact: This work validates a two-voxel
interleaved fMRS–fMRI protocol at 7T, enabling simultaneous measurement of
bilateral neurometabolic and BOLD changes during unilateral movement. The
approach paves the way for future studies of interhemispheric coordination and
excitation–inhibition dynamics in distributed cortical networks.
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461-06-012.
Multimodal Imaging of the cingulate cortex in Parkinson's Disease: Implications for Cognitive and Depression
Impact: This study highlights altered brain activity, impaired metabolism, and neurochemical imbalances in PD patients, providing insights into cognitive decline and depressive symptoms, potentially guiding early biomarkers and therapeutic strategies.
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461-06-013.
Assessing the Impact of Aerobic Exercise Capacity on Cerebral Metabolism and Glymphatic Function in Aging by PET-MRI
Impact:
This study reveals that improving aerobic exercise capacity promotes brain health by improving brain metabolism, preserving cerebrovascular integrity, and normalizing waste clearance. These results underscore exercise’s potential to preserve cerebral function and mitigate neurodegenerative processes associated with aging. |
© 2026 International Society for Magnetic Resonance in Medicine