Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Traditional Poster

Imaging Cerebrovascular Physiology in Stroke and Cerebral Arteriopathies

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Imaging Cerebrovascular Physiology in Stroke and Cerebral Arteriopathies
Traditional Poster
Neuro A
Wednesday, 13 May 2026
Traditional Posters | Exhibition Hall
16:00 - 16:55
Session Number: 570-07
No CME/CE Credit
This session focuses on advanced MRI techniques to characterize cerebrovascular hemodynamics and reactivity in stroke and cerebral arteriopathies. Presentations emphasize methodological innovations in BOLD, ASL, and angiographic imaging to improve assessment of vascular reserve, perfusion dynamics, and tissue viability.

  Figure 570-07-212.  Hemodynamic delay correction in breath-hold BOLD fMRI critically alters cerebrovascular reactivity interpretation in stroke
Rebecca Clements, Fatemeh Geranmayeh, Niamh Parkinson, Molly Bright
Northwestern University, Chicago, United States of America
Impact: Voxel-wise hemodynamic delay correction critically impacts CVR estimation in participants with stroke, particularly in brain regions with more extreme temporal offsets. Delay maps also aid physiological interpretation of CVR, helping distinguish vascular steal from impaired or collateral-dependent blood flow.
  Figure 570-07-213.  Assessment of Cerebrovascular Reactivity Using Breath-Hold BOLD-fMRI in Moyamoya Disease
Senmu Yao, Silu Chen, Liangliang Han, Bo Jiang, Yiwei Wang, Bing WU
The Seventh Medical Center, Chinese PLA General Hospital, Beijing, China
Impact: This breath-hold protocol enables widespread CVR assessment in China where intravenous acetazolamide is unavailable and MRI-compatible CO₂ delivery systems are nearly absent, providing clinicians an implementable tool for cerebrovascular reserve evaluation and surgical decision-making in Moyamoya disease.
  Figure 570-07-214.  Pathological changes in LSA morphology and downstream basal ganglia perfusion in MCA stenosis patients at 5T
Haocheng Sun, Mingyan Wu, Weihuan Fang, Jiawen Sun, Weiping Deng, Bin Liu, Naying He, Wenyan Kang, Jun Liu, Fuhua Yan, Xingfeng Shao
Shanghai Jiao Tong University, Shanghai, China
Impact: Findings highlight LSA stem and branch loss and caudate nuclei CBF reduction, supporting combined structural and perfusion assessment in patients with MCA stenosis.
  Figure 570-07-215.  Hybrid multi-delay pseudo-continuous ASL for improved visualization of inflow dynamics and robust quantification
Makoto Obara, Lena Vaclavu, Matthias van Osch, Osamu Togao, Koji Yamashita, Tatsuhiro Wada, Chiaki Tokunaga, Shota Ishida, Yu Ueda, Jihun Kwon, Masami Yoneyama, Marc Van Cauteren
Philips Japan, Tokyo, Japan
Impact: The optimized hybrid MD-pCASL demonstrated improved visualization of inflow hemodynamics with high SNR while maintaining high correlation with HYBRID-ISMRM in ATT and CBF, as predicted by the simulation results. This demonstrated its reliability and validity for clinical use.
  Figure 570-07-216.  Improved TOF-MRA visibility using an advanced combination of deep learning and algorithm-based processing in moyamoya disease
Noriyuki Fujima, Taro Fujiwara, Shotaro Fuchibe, Taro Igarashi, Joonsung Lee, Kohsuke Kudo
Hokkaido University Hospital, Sappro, Japan
Impact: 

The newly developed TOF-MRA technique, which integrates deep learning–based image reconstruction (DLR) with advanced computational background signal suppression, demonstrated significantly improved vessel visibility, particularly for small peripheral and collateral arteries, in patients with moyamoya disease.
  Figure 570-07-217.  Image Quality Assessment of Periventricular Anastomoses Using DANTE T1-SPACE
Yasutaka Fushimi, Sachi Okuchi, Akihiko Sakata, Takayuki Yamamoto, Satoshi Nakajima, Shuichi Ito, Masaki Umehana, Yongping Ma, Shin Morooka, Yusuke Utsunomiya, Akihiro Manabe, Yuta Urushibata, Alto Stemmer, Yuji Nakamoto
Kyoto University Graduate School of Medicine, Kyoto, Japan
Impact: 

Vessel-wall MRI using DANTE T1-SPACE with various image reconstruction was applied for moyamoya disease in this study, and Deep Resolve Gain achieved better parenchyma/vessel ratio and better signal-to-noise ratio for visualization of moyamoya vessels.
  Figure 570-07-218.  Comparing performance of ultra-low field MRI with high-field MRI and CT to detect AIS and ICH
Svenja Skadsem, Ayo Zahra, Aksel Leknes, Thomas Lindner, Ketil Oppedal, Soffien Ajmi, Martin Kurz, Muriel Bruchhage, Kathinka Kurz
University of Stavanger, STAVANGER, Norway
Impact: This study explores the use of ULF-MRI in patients with acute cerebral stroke. ULF-MRI could serve as a more accessible imaging tool for acute cerebral stroke aiming to treat patients earlier, potentially reducing morbidity and mortality on a global scale.
  Figure 570-07-219.  Assessment of Tissue Viability in Hyper Acute Stroke with Sodium MRI
Fernando Boada, Christian Licht, Azeezat Azeez, Georg Schramm, Jeremy Heit, Maarten Lansberg, Gregory Albers
Stanford Medicine, Stanford, United States of America
Impact: There is no image-based, quantitative, biomarker capable of identifying ischemic tissue destined to infarction in hyper acute stroke. Sodium MRI has the potential to fulfill this critical role, which could help improve outcome by reducing the risk of reperfusion injury.

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