Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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570-11-244.
Feasibility and Acceptability of Magnetic Resonance Imaging (MRI) for child neurodevelopmental research in rural Ethiopia
Impact: This study provides the first evidence on the feasibility and acceptability of MRI-based child development research in rural Ethiopia, highlighting community enthusiasm and key sociocultural and logistical considerations to guide ethical and sustainable expansion of MRI studies in low-resource settings.
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570-11-245.
Characterizing Microstructural Heterogeneity in Pediatric Leukodystrophies Using Multi-Compartment Diffusion MRI
Impact: This study demonstrates distinct white matter damage patterns in pediatric leukodystrophies using advanced diffusion MRI. Expanding and translating these findings into clinical practice could enable earlier diagnoses, improve disease monitoring, and clarify the underlying pathological mechanisms of these devastating diseases.
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570-11-246.
Exploring sources of variability in 1.5T and 3T T2-weighted 3D fetal brain MRI reconstructions
Impact: Differences in MRI scanner field strength, acquisition protocols and design, and post-processing reconstruction and analysis techniques contribute to subtle variations in image quality, contrast and morphology that can be difficult to account for, but which warrant further investigation.
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570-11-247.
DTI-ALPS Reveals Growth Hormone Therapy Modulates Glymphatic System Function in Short Stature Children: A Longitudinal Study
Impact: This study suggests a novel role for growth hormone in neurodevelopmental pathways with potential
implications for neuroprotective strategies, particularly in those with comorbid
neurodevelopmental disorders.
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570-11-248.
DTI tractography reveals HIV exposure-related changes in microstructural integrity detectable at birth
Impact: Prenatal exposure to HIV/ART appears to affect white matter microstructure in neonates without HIV infection. Differences in microstructure observed in projection fibres to the motor cortex improve our understanding of how in-utero exposure to HIV/ART may affect visual motor integration.
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570-11-249.
Utilization of Data-Driven Multivariate Decision Tree Age-Sex Stratification of Pediatric Spinal Cord MR Images
Impact: This work offers ready-to-adopt grouping rules for pediatric spinal cord MRI in ages 6-17, improving statistical power, fairness of case-control comparisons, and reproducibility in normative and disease studies.
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570-11-250.
TWIST Quantitative Analysis for Differentiating Pediatric Neuroblastoma from Nephroblastoma
Impact: This TWIST MRI-based analysis may
help differentiate neuroblastoma from nephroblastoma, enhancing diagnostic
accuracy in pediatric oncology, enabling earlier targeted interventions,
optimizing treatment planning, and reducing the need for invasive biopsies and
associated risks in young patients.
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570-11-251.
Cerebrospinal fluid stroke volume is decreased in pediatric Chiari 1 subjects
Impact: This study investigates a large pediatric cohort and establishes stroke volume as an important metric in this disease group. Further research using this metric may allow clinicians to better differentiate who will benefit from corrective surgery.
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570-11-252.
Evaluating Demographic Bias and Data Reliability Across Multi-Site Pediatric MRI Cohorts
Impact: This study demonstrates how
demographic disparities and site-level imbalances in pediatric MRI influence data
quality and reliability by identifying biases that must be addressed to achieve
fair, reproducible, and generalizable pipelines in neuroimaging research with AI and statistical modelling.
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