Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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664-01-001.
Functional MRI during cerebellar deep brain stimulation: initial findings and thermal safety
Impact: This proof-of-concept work demonstrates
for the first time that informative fMRI data can be safely acquired during
cerebellar DBS. Using fMRI to study cerebellar DBS mechanisms can both guide treatment
optimization and provide broader insights into cerebellar function.
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664-01-002.
Functional gradients of the neonatal cerebellum
Impact: This
study characterises neonatal intra-cerebellar and cerebro-cerebellar functional gradients for the first time. This framework supports the mapping of early development of cerebellar functional architecture that underpins later cognitive and behavioural development.
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664-01-003.
Cerebellar-mediated imbalance of multiple neural circuits in Internet Gaming Disorder
Impact: This study establishes the cerebellum as a multimodal hub in IGD, providing precise targets for neuromodulation therapy and reshaping the understanding of its neural circuitry beyond traditional pathways.
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664-01-004.
Cerebellar atrophy modulates freezing of gait in multiple system atrophy through cognitive dysfunction
Impact: This study identifies cerebellar Crus II atrophy as a structural biomarker linking cognitive dysfunction to freezing of gait in MSA, enabling early risk stratification and guiding future neuromodulation or cognitive interventions to improve mobility and quality of life in patients.
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664-01-005.
Patient risk stratification of Alzheimer's disease based on the functional connectivity changes of cerebellar subregions
Impact: Cerebellar functional connectivity alterations provide novel imaging biomarkers for early AD/MCI diagnosis and clinical stratification.
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664-01-006.
Progressive Reconfiguration of Static and Dynamic Functional Network Connectivity in Spinocerebellar Ataxia Type 3
Impact: SCA3 patients exhibited gradually progressive large-scale functional network reconfiguration. These results collectively illuminate the evolving landscape of network-level dysfunction in SCA3 and provide new insights into its underlying neural mechanisms.
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664-01-007.
Functional motor network mapping with resting-state, task-based, and concurrent TMS-fMRI paradigms using the RF cap
Impact: By perturbing motor cortex (M1) with adjustable TMS intensity and
measuring whole-brain responses, this work provides comprehensive causal
network mapping complementing task-based and resting-state fMRI, enabling
identification of optimal cortical targets and stimulation parameters for
personalized neuromodulation.
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664-01-008.
Comparative Evaluation of Automated Cerebellar Parcellation Pipelines in Degenerative Cerebellar Diseases
Impact: Automated
cerebellar parcellation tools reliably detect cerebellar atrophy but produce
varying volume estimates. Pipeline selection critically affects quantitative
outcomes in clinical trials. CerebNet and SPM12 offer optimal performance for
cross-sectional and longitudinal analyses, respectively.
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664-01-009.
Resting-State BOLD Detects Diaschisis-Related Cerebellar Cerebrovascular Reactivity in Unilateral Cerebrovascular Occlusion
Impact: Resting-state
BOLD enables quantitative assessment of cerebellar cerebrovascular reactivity
and reliable detection of crossed cerebellar diaschisis, demonstrating comparable
diagnostic accuracy to 18F-FDG PET. This task-free method offers a practical
tool for evaluating cerebellar hemodynamic impairment in cerebrovascular occlusive disease.
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664-01-010.
Features of brain regional homogeneity correlated with response inhibition in children with ADHD:effect of digital therapy
Impact: This study identifies neural mechanisms underlying digital therapy for ADHD, showing improved response inhibition and altered fronto-striatal-cerebellar synchronization, providing new neuroimaging evidence and potential targets for personalized digital interventions in neurodevelopmental disorders.
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664-01-011.
Causal and functional dynamics of visuomotor network demonstrate excitatory/inhibitory alterations in multiple sclerosis
Impact: Integrating
information from DCM and TVB reveals how disrupted excitation/inhibition
balance drives clinical worsening in MS.
Merging information from effective connectivity and simulated brain dynamics
offers mechanistic biomarkers for monitoring disease progression and the future tailoring of patient-specific interventions.
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664-01-012.
Brain Functional Network Abnormalities and Repetitive Transcranial Magnetic Stimulation Modulation Mechanisms in SCA3
Impact: This study demonstrates that rTMS can effectively regulate abnormal functional network patterns in SCA3, improving motor symptoms. It opens new avenues for non-invasive neuromodulation therapies and highlights the potential of CPM for personalized predictions in neurodegenerative diseases.
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664-01-013.
Involvement of Subcortical structures in the Action Observation Network investigated at Ultra-High Field
Impact: We investigated with BOLD-fMRI at UHF
the involvement of subcortical nuclei in the Action-Observation Network,
revealing activations in the pulvinar and putamen. These structures, part of
visuomotor pathways, may contribute to motor resonance mechanisms and
inhibition of motor execution.
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© 2026 International Society for Magnetic Resonance in Medicine