Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Breast MRI: Technical Developments

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Breast MRI: Technical Developments
Digital Poster
Body
Tuesday, 12 May 2026
Digital Posters Row C
16:55 - 17:50
Session Number: 462-06
No CME/CE Credit
This session present technical developments in breast MRI, focussing on both hard- and software optimisation, and the consequences of these for clinical breast MRI interpretation.
Skill Level: Intermediate

  Figure 462-06-001.  High-resolution supine breast MRI with free-breathing 3D Cones
Judith Zimmermann, Marcus Alley, Xuetong Zhou, Jana Vincent, fraser robb, Bruce Daniel, Brian Hargreaves
Stanford University, Stanford, United States of America
Impact: Free-breathing 3D Cones offers high encoding and SNR efficiency for supine breast MRI with high spatial resolution. We have shown the inherent insensitivity to respiratory motion, although further image sharpness can be achieved by adding on retrospective motion correction.
  Figure 462-06-002.  Multi-Vendor Compatible Rx-only Quadrature Wireless Coil for MR-mammography at 1.5T
Summa Cum Laude
Pavel Tikhonov, Aleksandr Fedotov, Alexandr Kozachenko, Georgiy Solomakha, Anna Hurshkainen
ITMO University, Saint Petersburg, Russian Federation
Impact: We demonstrate the first Rx-only wireless coil for 1.5T mammography showing image quality comparable to dedicated multi-channel commercial coil.
  Figure 462-06-003.  Standardizing Breast Diffusion MRI: An Anthropomorphic 2D Phantom for Quantitative and Reproducible ADC Measurements
Todor Karaulanov, Chamni Jayarathna, Callie Weiant, John Wenzel, Shannon John, William Hollander
CaliberMRI, Boulder, United States of America
Impact: A morphologically accurate, patient-derived breast phantom filled with NIST-traceable PVP diffusion mimics provides a stable, anatomically realistic reference for DWI calibration and QA/QC. It enables harmonized quantitative breast DWI across scanners, supporting reproducible ADC measurement and cross-site standardization.
  Figure 462-06-004.  Robust fat suppression for high-resolution body diffusion MRI on 5T
Fan Liu, Yiming Dong, Wending Tang, Simin Liu, Hualu Han, Shuo Chen, Guangqi Li, Diwei Shi, Xin Shao, Yuancheng Jiang, Wenbo Lyu, Huadan Xue, Gumuyang Zhang, Hao Sun, Hua Guo
Tsinghua University, Beijing, China
Impact: A robust and low-SAR fat suppression technique was designed specifically for 5T high-resolution DWI. As a potential alternative to conventional fat suppression techniques, the novel method effectively reduces fat-related chemical-shift artifacts, thereby enhancing whole-body disease screening and diagnosis.
  Figure 462-06-005.  Quantifying MRI Sequence-Specific Distortion in a Breast Phantom via CT Co-Registration and Susceptibility Simulation
Klara Mišak, Agnieszka Sierhej, Chris Clark, Kelley Ferreira, Sienna Griffin-Shaw, Felix Roberts, David Roddy, Simon Walker-Samuel, Matt Cashmore
University College London, London, United Kingdom
Impact: An anthropomorphic breast phantom quantified sequence specific distortion using MRI to CT registration and simulations. Measured errors exceeded susceptibility predictions, implying gradient nonlinearity dominates. The framework informs correction, registration selection, and QA standards for quantitative metrics and MRI guided interventions.
  Figure 462-06-006.  Deuterium Metabolic Imaging (DMI) in human breast – proof of concept and reproducibility
Claudius Mathy, Luka Stam, Mark Gosselink, Sonja Vliek, Dimitri Welting, Cezar Alborahal, Michael Uder, Tobias Bäuerle, Armin NAGEL, Jannie Wijnen, Dennis Klomp
University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
Impact: Deuterium metabolic imaging (DMI) is shown to be feasible and reproducible in the human breast of 6 healthy volunteers. This shows its potential for further investigation of this novel metabolic imaging technique in initial metabolic patient measurements.
  Figure 462-06-007.  Design and Evaluation of Helical Coils for Low-Field, Low-Cost Breast MRI in a Non-Uniform Rampable B0 Field-Cycling System
SAJAD HOSSEINNEZHADIAN, Yonghyun Ha, Chenhao Sun, Ryan Gross, Anja Samardzija, Flor Parra Rodriguez, Heng Sun, Sebastian Theilenberg, Tao Li, Guang Yang, Troy Williams Gelobter, Mark DelMonte, Horace Zhang, Gigi Galiana, R. Todd Constable
Yale University, New Haven, United States of America
Impact: This study demonstrates improved B₁ homogeneity and SNR in low-field breast MRI using optimized helical RF coils and integrated shielding. The approach enables cost-effective, anatomically tailored imaging systems, supporting broader accessibility and future in-vivo validation.
  Figure 462-06-008.  Repeatability of 1H/23Na MRI measurements in healthy breast tissues at 3 T
Baptiste Busi, Anne Adlung, Dimitri Martel, Linda Moy, Doris Leithner, Ryan Brown, Guillaume Madelin
Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, United States of America
Impact: We assessed the repeatability of a 1H/23Na MRI protocol (DTI, CSE MRI, MRF, 23Na MRI) in healthy breast tissue at 3 T before it is applied to monitor early effect of neoadjuvant chemotherapy in breast cancer patients.
  Figure 462-06-009.  Efficient MR fingerprinting acquisition & phase-reconstruction framework for quantitative fat–water relaxometry in the breast
Shahrzad Moinian, Zhilang Qiu, Yong Chen, Dan Ma
Duke University School of Medicine, Durham, United States of America
Impact: This efficient fat-fibroglandular relaxometry quantification framework lays the groundwork for high‑resolution breast tissue visualization and accurate quantitative characterization, providing a foundation for future studies on small‑lesion characterization, early biomarker development, and translation of multiparametric MRI to advanced breast cancer applications.
  Figure 462-06-010.  Non-Invasive Characterization of Breast Tumors Using MRE-Derived Stiffness
Akhil Deavela, Brandy Griffith, Jeffrey Hawley, Kristin Thompson , Manjunathan Nanjappa, Arunark Kolipaka
The Ohio State University, Columbus, United States of America
Impact: The correlation between MRE-derived tumor stiffness and characteristics of DCE-MRI supports the potential that MRE has in enhancing diagnostic precision using a non-contrast method and prompts further investigation into the relationship between MRE-derived tumor stiffness and other breast tumor characteristics.
  Figure 462-06-011.  Improving Fatty Acid Composition Estimation in Mammary Adipose Tissue with Varying Fat Fraction
Woocheol Jang, Michele Drotman, Linda Moy, Gene Kim, Jinseok Lee
Weill Cornell Medical College, New York, United States of America
Impact: A voxel-wise physics-informed unsupervised framework accurately estimated FAC maps in mammary adipose tissue, achieving robust FAC estimation for voxels with 50~100 % fat fraction that are often found along the boundary between adipose and fibroglandular tissues in the breast.
  Figure 462-06-012.  Blind estimation versus direct measurement of the arterial input function in dynamic contrast-enhanced MRI of the breast
Jake Cray, Jiří Vitouš, Radovan Jiřík, Sofya Titarenko, David Buckley
Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom
Impact: A validated method of obtaining the arterial input function from tissue data alone would provide a step change in the clinical adoption of quantitative dynamic contrast-enhanced MRI. Our results suggest that blind estimation offers a promising opportunity to achieve this.
  Figure 462-06-013.  Fast DCE Breast MRI using Deep Learning based Acceleration: Initial Experiences and Future Clinical Directions
Sherry Huang, Ty Cashen, Arnaud Guidon, Roberta Strigel, Leah Henze Bancroft
GE HealthCare, Rochester, United States of America
Impact: This study demonstrates the feasibility of a DL-based acceleration technique for T1-weighted DCE sequence which reduces the acquisition time up to 45% without impacting the image quality. This technique has the potential to significantly reduce breast MRI exam time.
  Figure 462-06-014.  Static and dynamic parallel transmit pulse design for a 4Tx/16Rx breast coil array at 7T
Nico Egger, Laurent Ruck, Sophia Nagelstraßer, Jürgen Herrler, Andreas Bitz, Titus Lanz, Michael Uder, Sebastian Bickelhaupt, Armin NAGEL
University Hospital Erlangen (UKER), Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
Impact: This work demonstrates the feasibility of pTx pulse design with a 4Tx/16Rx breast coil, achieving improved flip angle homogeneity and mean squared B₁⁺ uniformity. The results were based on preliminary phantom measurements but suggest potential for future in vivo applications.
  Figure 462-06-015.  Anatomically Shaped Wireless RF Coil for Enhanced Breast MRI Performance at 1.5 T
Alexey Slobozhanyuk, Viktor Puchnin, Alena Shchelokova
Nurisight, Dubai, United Arab Emirates
Impact: Wireless breast coils can enhance image quality, reduce RF power and SAR, and simplify workflow without requiring scanner modifications. Their low cost and compatibility make them an attractive alternative or complement to conventional dedicated breast coils.
  Figure 462-06-016.  Breast-segmented, dynamic slice-by-slice B0 shimming in unilateral breast MRI
Ante Zhu, Chitresh Bhushan, Lisa Wilmes, Katja Pinker-Domenig, Pingni Wang, Vanika Singhal, Wen Li, Nola Hylton, Bonnie Joe, Patricia Lan, Seung-Kyun Lee
GE HealthCare, San Ramon, United States of America
Impact: Breast cancer detection and characterization can benefit from high-quality DWI with reduced image distortion and improved fat suppression by using a breast-segmented, optimized dynamic slice-by-slice B0 shimming for each breast individually, which is applicable to any MRI system.

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