Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Oral

Inside the Bean: Advances in Renal MRI

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Inside the Bean: Advances in Renal MRI
Oral
Body
Tuesday, 12 May 2026
Hall 1B
08:20 - 10:10
Moderators: Nirbhay Yadav & Neeraja Mahalingam
Session Number: 402-02
CME/CE Credit Available
Recent advances in renal MRI enable non-contrast, quantitative assessment of renal dysfunction and characterization of renal masses. Techniques such as DWI, ASL, BOLD, APT, and pH imaging provide functional, metabolic, and microstructural information, with improving diagnosis, risk stratification, and tumor characterization, particularly in patients with impaired renal function and renal masses.
Skill Level: Intermediate

08:20 Figure 402-02-001.  Evaluation of Renal Injury in Transplanted Kidneys by Amide Proton Transfer Magnetic Resonance Imaging
Xintian Yu, Liang Pan, Jiule Ding, Peng Wu, Jinggang Zhang, Jie Chen, Wei Xing
Third Affiliated Hospital of Suzhou University & First People's Hospital of Changzhou, Changzhou, China
Impact: APT-MRI can assess the degree of damage of the transplanted kidney and provide a basis for clinical diagnosis and treatment.
08:31 Figure 402-02-002.  Multi-b-value Diffusion, T1, R2*, and ASL MRI Classify Renal Allograft Pathology and Allograft Outcome: Interim Results
Magna Cum Laude
Mira Liu, Jonathan Dyke, Ian Bolger, Sergio Calle, Ananda Kimm-Drapeau, Tanner Crews, Surya Seshan, Steven Salvatore, Isaac Stillman, Thangamani Muthukumar, Bachir Taouli, Samira Farouk, Sara Lewis, Octavia Bane
Icahn School of Medicine at Mount Sinai, New York, United States of America
Impact: MRI of renal allografts may capture in vivo pathological changes and enable non-invasive characterization to inform decisions to pursue biopsy or change the medication regimen, as well as longitudinal monitoring in clinical trials of anti-fibrotic medications.
08:42 Figure 402-02-003.  Alterations in functional MRI parameters of the fetal kidney associated with preterm delivery
Charline BRADSHAW, Alena Uus, Molly Dillon, Anangsha Kumar, Megan Hall, Srividhya Sankaran, MARY RUTHERFORD, Lisa Story, Jana Hutter, Kelly Payette
Kings College London, London, United Kingdom
Impact: Altered renal development commences antenatally in fetuses who deliver preterm, preceding detectable changes in renal volume. Fetal renal T2* is a promising imaging biomarker of renal development offering potential for early identification and monitoring.
08:53 Figure 402-02-004.  Diffusion-Exchange MRI for Contrast-Free Renal Function Assessment: A Feasibility Study
Cemre Ariyurek, Miriam Hewlett, Liam Timms, Mustafa Utkur, Sila Kurugol, Evren Özarslan, Onur Afacan
Boston Children's Hospital and Harvard Medical School, Boston, United States of America
Impact: This study assesses feasibility of diffusion-exchange MRI as a contrast and radiation-free renal water exchange quantification, providing a promising noninvasive, repeatable assessment of kidney function, particularly valuable for pediatric populations requiring longitudinal monitoring without exposure to gadolinium or ionizing radiation.
09:04 Figure 402-02-005.  Low Rank Motion Correction for IVIM and Diffusion Spectrum Quantification for Indeterminate Renal Masses
Ningjun Wang, Michael Jaroszewicz, Yun Jiang, Zhengguo Tan, Jesse Hamilton, Vikas Gulani, Hero Hussain, Matthew Davenport, Nicole Seiberlich, Gastao Cruz
University of Michigan, Ann Arbor, United States of America
Impact: IVIM and diffusion spectrum quantification using a fast free-breathing diffusion EPI protocol is feasible in healthy subjects and renal mass patients. This type of quantitative diffusion data could help in the characterization of indeterminate renal masses.
09:15 Figure 402-02-006.  Deuterium metabolic imaging detects dynamic glucose changes in renal masses
Andre Wendlinger, Ines Horvat-Menih, Mary McLean, Pascal Wodtke, Maria Zamora-Morales, Jonathan Birchall, Joshua Kaggie, Alixander Khan, Ashley Grimmer, Elizabeth Latimer, Marta Wylot, James Armitage, Thomas Mitchell, Grant Stewart, Ferdia Gallagher
University of Cambridge, Cambridge, United Kingdom
Impact: This foundational study establishes the feasibility of 3T Deuterium Metabolic Imaging (DMI) for human renal masses. The results provide a clear roadmap for methodological optimization, paving the way for larger clinical trials of this non-invasive technique.
09:26 Figure 402-02-007.  What is the effect of a breath-hold on renal BOLD MRI scans?
AMPC Selected
Anna Griffith, Eve Shalom, Kanishka Sharma, Kywe Soe, Ho-Fung Chan, Guilhem Collier, Neil Stewart, Steven Sourbron, Joao Periquito
The University of Sheffield, Sheffield, United Kingdom
Impact: Detailing renal BOLD changes from autoregulatory mechanisms may reveal impaired renal vasoreactivity, a feature of early diabetic kidney disease, and serve as a potential biomarker for early detection and monitoring.
09:37 Figure 402-02-008.  pH imaging using hyperpolarized [1,5-13C2]Z-OMPD in kidneys of pig models at 3 T
Magna Cum Laude
Martin Grashei, Esben Hansen, Pascal Wodtke, Uffe Kjærgaard, Alixander Khan, Kristine Hinzel, Tau Vendelboe, Duy Anh Dang, Ferdia Gallagher, Christoffer Laustsen, Franz Schilling
Technical University of Munich (TUM), Munich, Germany
Impact: This study demonstrates reliable large-dose production of hyperpolarized [1,5-13C2]Z-OMPD for in vivo pH imaging. 13C MRI on healthy pig kidneys on a clinical 3 T scanner enables reproducible compartmental pH mapping, proving feasibility for large-animal pH imaging.
09:48 Figure 402-02-009.  Cross-validation of intravoxel incoherent motion metrics with quantitative and qualitative histology in excised kidney tumors
Nima Gilani, Deepesh Goel, Valeria Mezzano, Gyles Ward, Fang-Ming Deng, Dibash Basukala, Nalini Jeet, Artem Mikheev, Mary Bruno, William C Huang, Vasishta S Tatapudi, Seon-Hi Shin, Hersh Chandarana, Eric Sigmund
Center for Advanced Imaging Innovation and Research (CAI²R), New York University Grossman School of Medicine, New York, United States of America
Impact: IVIM parameters demonstrate strong correlations with histopathological features, potentially enabling non-invasive tumor characterization to reduce unnecessary biopsies or surgeries, and improve surgical planning through pre-operative tissue assessment in renal cancer patients.

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