Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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363-06-001.
Hemodynamics and Endomyocardial Injury in Severe Aortic Stenosis: Insights from 4D Flow CMR, catheter Pressure and histologic
Impact: The results of this study suggested that beyond ischemia, shear forces may play a central role in AS-related myocardial remodeling, highlighting wall shear stress derive from 4d flow CMR as a potential imaging biomarker and therapeutic target.
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363-06-002.
3D Phase Contrast using Balanced Steady-State Free Precession (PC-SSFP) for Improved 4D Flow at Clinical Field Strengths
Impact: A non-contrast-enhanced 4D
flow MRI using bSSFP was developed at the most commonly used clinical
field strengths (1.5T and 3T), which improved image quality and
accurately measured flow velocity and volume, showing its potential for
more robust intracardiac flow evaluations.
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363-06-003.
Accelerated Self-gated Dual-VENC 4D Flow enabled using High-VENC with Differentiated Resolution (HDR)
Impact: Our
accelerated HDR technique makes accurate, free-breathing dual-VENC 4D Flow
clinically practical. This enables robust velocity quantification in more
patients, including those unable to hold their breath, improving diagnostic
workflow and making comprehensive flow imaging more routine.
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363-06-004.
Intracranial 4D Flow of IIH patients pre and post lumbar puncture identifies altered pulse wave modulation
Impact: Intracranial 4D flow analysis pre- and post-lumbar puncture in
suspected IIH patients shows stable cerebral blood flow, but marked changes in hemodynamic
regulation by the vasculature, indicated by altered vascular effective
compliance and pulse wave modulation.
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363-06-005.
Image2Flow Transient: Fast Estimation of Transient Pulmonary Artery Flow Fields from 3D Cardiac MRI
Impact: We developed a deep learning model that generates a 3D pulmonary artery mesh with time-varying flow fields from a single 3D cardiac MRI input—the first to generate both volumetric mesh and transient CFD results in a single inference.
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363-06-006.
Camera-based Respiratory Binning for 4D flow MRI at 0.6T
Impact: Camera-based
respiratory binning provides a viable alternative at lower field strengths,
where MR-based binning may be limited by reduced SNR, particularly in subjects
with larger body-size or higher fat-mass.
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363-06-007.
Dampened Limbic and Striatal Pulsatility in Idiopathic Intracranial Hypertension: Insights from q-aMRI and Flow MRI
Impact: Conventional flow processing techniques are poor at distinguishing controls from IIH pre- or post-LP. Up-and-coming advanced MRI analysis software for 4D CBF and q-aMRI for regional brain displacement reveal marked group differences, paving a new way to understand pressure-related disorders.
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363-06-008.
Intracranial 4D Flow MRI across field strengths – experimental in-vitro study at 1.5, 3, and 7T
Impact: Using a neurovascular flow phantom imaged at 1.5, 3, and 7T, we examined field strength effects on 4D Flow MRI. Maximum VNR increased with field strength, but both 1.5T and 7T showed lower peak and mean flow rates than 3T.
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363-06-009.
Asymmetric 5-point 4D Flow MRI for dual-VENC velocity and turbulent kinetic energy encoding
Impact: The
proposed asymmetric 5-point scheme facilitates clinical adoption of 4D Flow MRI
as it accurately resolves low and high velocities, as well as turbulent kinetic
energy, with minimal addition in scan time.
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363-06-010.
Validation of deep-learning-based super-resolution for 4D-flow MRI haemodynamic quantification
Impact: By
recovering fine-scale flow features and improving haemodynamic accuracy,
deep-learning-based super-resolution can help establish 4D-flow MRI as a more
quantitative and clinically reliable tool for assessing vascular function and
disease.
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363-06-011.
Empirical Correction of the Spatial Dependence of VENC due to MRI Gradient Non-linearities using a Rotational Phantom
Impact: Spatially-dependent VENC correction enables more accurate quantitative flow assessment across extended FOVs in PC-MRI. A simple phantom measurement and 30min scan time may enable broad acceptance.
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363-06-012.
4D bSSFP MRI and 4D flow MRI to assess changes in aortic motion and hemodynamics after root replacement surgery in Marfan
Impact: Pre- and
post-surgery 4D bSSFP and flow MRI showed that placing a graft decreases ascending
aortic displacement and distensibility and increases velocity. In the proximal
descending aorta, changes in distensibility were noted that could alter wall properties
in the long-term.
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363-06-013.
Assessment of Left Ventricular Hemodynamics with 4D Flow MRI in Hypertensive Patients Post-Treatment
Impact: Incorporating 4D Flow MRI-based KE assessment enhances the non-invasive evaluation of treatment response in hypertension. Blood pressure control and reverse structural remodeling emerged as key independent predictors of hemodynamic recovery, supporting their potential as functional biomarkers for guiding personalized therapy.
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363-06-014.
Cerebrovascular 5D flow MRI
Impact: We propose a high-resolution
cerebrovascular 5D flow MRI framework, facilitating full-field quantification of
respiratory flow modulation in complex arterial and venous structures and
modulation of arterial-to-venous dynamics such as transit time and potential 3D
hemodynamic biomarkers such as relative pressure.
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363-06-015.
Ferumoxytol-enhanced whole-heart 4D flow on a commercial 0.55T system
Impact: This work demonstrates the feasibility of ferumoxytol-enhanced whole-heart 4D flow MRI at 0.55T with preserved net-flow accuracy versus 3T. These results support low-cost, contrast-enhanced whole-heart flow imaging at lower field strength and motivate continued development toward broader clinical access.
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363-06-016.
Hemodynamics contribute to pulsatile tinnitus in sigmoid sinus wall dehiscence with idiopathic intracranial hypertension
Impact: Hemodynamic abnormalities may help to understand the mechanism of sigmoid sinus wall dehiscence-pulsatile
tinnitus patients with idiopathic intracranial hypertension. The combination of hemodynamic indicators may serve as a valuable noninvasive tool to improve the accuracy of etiological
diagnosis.
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© 2026 International Society for Magnetic Resonance in Medicine