Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Oral

Multimodal and Innovative Design

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Multimodal and Innovative Design
Oral
Brain Function & fMRI
Monday, 11 May 2026
Ballroom East
16:10 - 18:00
Moderators: Nathalie Just & Wenli Li
Session Number: 304-04
No CME/CE Credit
This session groups abstracts that pair BOLD-based fMRI with other brain function techniques
Skill Level: Intermediate

16:10 Figure 304-04-001.  Visual feedback incongruence modulates motor cortex activity: fMRI evidence for a finger-tapping illusion
Aneurin Kennerley, Nikki Bonett, Oliver Mundell, Libby Henthorn, Elisa Zamboni
Manchester Metropolitan University, Manchester, United Kingdom
Impact: This study demonstrates that visual input can dynamically reshape sensorimotor representations, via a feedback-driven mechanism. Visually mediated modulations may underpin neuroplastic changes in conditions where distorted body representations contribute to altered sensory experience and motor control (e.g., phantom limb, osteoarthritis).
16:21 Figure 304-04-002.  In-vivo Demonstrations of a Flexible Head Cap Enabling Multimodal and Posture Adaptable Neuroimaging
Summa Cum Laude
Julian Maravilla, Omer Sharon, Shreya Ramachandran, Chunlei Liu, Ana Arias, Michael Lustig
University of California, Berkeley, United States of America
Impact: A flexible Head-Cap Array enables EEG-fMRI, TMS-fMRI, and adaptable MRI in natural postures and anatomically challenging subjects, overcoming the comfort and accessibility barriers of rigid coils to advance inclusive, patient-centered, and multimodal neuroimaging.
16:32 Figure 304-04-003.  Going wearable in simultaneous EEG-fMRI at 7T: 8TxRx dipole antenna combined with a 10Rx-only twisted-pair coil array
AMPC Selected
Elizaveta Shegurova, Andreas Lu, Leen Bou Khaled, Thanh Phong Lê, Jules Vliem, Katarzyna Pierzchala, Emilie Sleight, Jonathan Wirsich, Frédéric Grouiller, Irena Zivkovic, Dimitri Van De Ville, Dimitrios Karampinos, Daniel Wenz
CIBM Center for Biomedical Imaging, Lausanne, Switzerland
Impact: This work establishes the feasibility of combining flexible TP receive arrays with transceive dipole antennas in the presence of an EEG cap, demonstrating potential for future wearable multimodal neuroimaging at 7T.
16:43 Figure 304-04-004.  Simultaneous fMRI and Optical Imaging Reveal a Broadband Cortical Neuronal Fingerprint from Theta to Infraslow Frequencies
Wen-Ju Pan, Lauren Daley, Lisa Meyer-Baese, Dieter Jaeger, Shella Keilholz
Emory/Georgia Tech, Atlanta, United States of America
Impact: We directly validate fMRI functional connectivity as a true representation of cortical neuronal synchronization. Simultaneous fMRI and optical imaging reveal that resting-state FC reflects broadband slow-frequency neuronal coupling, spanning theta to infraslow rhythms.
16:54 Figure 304-04-005.  Validation of Neural-Activity-Related Sodium (NARS) fMRI Using Simultaneous Glutamate Fiber Photometry at 14 Tesla
Xin Yu, Xiaochen Liu, Yuanyuan Jiang, Grace YU, Nivetha Pasupathy, David Hike, Xiaoqing Zhou
Massachusetts General Hospital and Harvard Medical School, Boston, United States of America
Impact: 

We establish direct neuronal correlation of NARS-fMRI using simultaneous glutamate signals, analogous to local field potentials. This provides a foundation for translating sodium-based fMRI to human functional mapping and enables mechanistic investigation of quadrupolar relaxation dynamics using living cerebral organoids.
17:05 Figure 304-04-006.  Interleaved fMRS/fMRI of the somatosensory cortex at 7T
Claire Lucas, Susan Francis, Adam Berrington
University of Nottingham, Nottingham, United Kingdom
Impact: We demonstrate that interleaved fMRS/fMRI can be applied to the somatosensory system to study glutamate changes during stimulation, with increases greatest at stimulus onset. This allows direct comparison of metabolic and haemodynamic responses.
17:16 Figure 304-04-007.  Cross-species fMRI signature of Locus Coeruleus-driven brain state transitions
Francesca Barcellini, Georgios Foustoukos, Daniel Wenz, Brandon Munn, James Shine, Laura Fernandez, Anita Luthi, Valerio Zerbi
Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
Impact: We describe a conserved fMRI signature of locus coeruleus activation across rodents and humans. This neuromodulatory signature provides a cross-species biomarker of arousal dynamics and a path toward individualized mapping of internal brain-state transitions via resting-state fMRI.
17:27 Figure 304-04-008.  Zona Incerta Neural Activity Regulates Sensorimotor Cortical-Subcortical Network Dynamics through Hypothalamus and Striatum
Junjian Wen, Linshan Xie, Ed X Wu, Alex T. L. Leong
The University of Hong Kong, Hong Kong, China
Impact: This study reveals how the zona incerta regulates large-scale sensorimotor cortical and subcortical network dynamics, providing a mechanistic framework for its integrative role in sensory and motor processing. These insights will prompt future investigations into ZI-targeted interventions for sensorimotor dysfunctions.

17:38 Figure 304-04-009.  Assessing the Effects of Caffeine on Brain Connectivity Using DASL and BOLD fMRI
Yakun Zhang, Shichun Chen, Jinnat Mahmood, Darcy Miller, Jodi Weinstein, Xiang He, Weiying Dai
The State University of New York at Binghamton, Binghamton, United States of America
Impact: Dynamic arterial spin labeling (DASL) may detect resting state functional connectivity (rsFC) with the hippocampus and other ventral brain regions more robustly than BOLD fMRI. Replication and validation are needed to confirm that DASL-derived rsFC accurately reflects brain function.
17:49 Figure 304-04-010.  Quantifying Arousal-Driven Variability in fMRI Using Eye Closure Metrics and Connectivity Analyses
Elif Can, Kadir Berat YILDIRIM, Kübra Eren, Cem Karakuzu, Belal TAVASHI, Lina Mahmoud Saleh Alqam, Şirin Yağmur Abacı, Sinem Aytaç, Fatmatüzzehra Uçal, Alp Dinçer, Pinar Özbay
Boğaziçi University Institute of Biomedical Engineering, Istanbul, Turkey
Impact: We address a limitation in rsfMRI: the lack of arousal monitoring and the confounding arousal contributions to the BOLD signal. This study enhances the reliability and utility of fMRI for clinical and neuroscience applications.

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