Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition

All About Neuroinflammation

Traditional Poster

Neuro A

Monday, 11 May 2026

Traditional Posters | Exhibition Hall

08:20 - 09:15

Session Number: 370-01

No CME/CE Credit

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This traditional poster session showcases quantitative and multiparametric neuroimaging approaches for detecting tissue damage, monitoring disease evolution, and predicting clinical outcomes in neuroinflammation, with a strong focus on multiple sclerosis. Presentations highlight diffusion MRI, quantitative T1/PD mapping, myelin-sensitive techniques, and multiparametric biomarkers to characterize demyelination, remyelination, and early tissue injury. Several posters also explore functional reorganization, network alterations, and AI-accelerated imaging across related neurological and systemic conditions. Together, the session emphasizes the clinical and biological value of quantitative MRI for earlier detection, better phenotyping, and improved prognostication.

		370-01-001. Diffusion Tensor Imaging in Thalamus Differentiates People with Multiple Sclerosis whose Disability Progresses Over 2 Years Augustine Rosati, Olivia Kalau, Sharada Balaji, Irene Vavasour, Roger Tam, Anthony Traboulsee, Jiwon Oh, Poljanka Johnson, Shannon Kolind University of Toronto, Toronto, Canada Impact: There are no biomarkers of MS clinical progression. Participants who showed clinical progression over 2 years demonstrated increased thalamic radial, axial, and mean diffusivity, and decreased fractional anisotropy at baseline. Thalamic DTI markers could be used as a predictive biomarker.
		370-01-002. Quantitative T1/PD² Ratio to Differentiate Demyelination and Remyelination in Multiple Sclerosis Sarah Wright, Scotty McKay, Jean Ramos Bou, Vivian Truong, Fen Bao, E. Mark Haacke, Anza Memon, Yulin Ge, Yongsheng Chen Wayne State University School of Medicine, Detroit, United States of America Impact: T1-to-PD² Ratio (TPR) has the potential to serve as a non-invasive biomarker for assessing MS lesion pathology, offering a novel way to visualize demyelination and remyelination. It enables in vivo monitoring of lesion evolution, disease progression, and therapy response.
		370-01-003. Quantitative Parameter Mapping Reveals Alterations in Normal-Appearing White Matter in Multiple Sclerosis Emi Sato, Yuki Kanazawa, Masafumi Harada, Yo Taniguchi, Yuki Matsumoto, Masahiro Takizawa Kumamoto University, Chuo-Ku, Japan Impact: Our study demonstrates that multiple quantitative MRI parameters can sensitively detect subtle alterations in NAWM and characterize spatial lesion heterogeneity in MS. This approach may enable earlier detection of disease-related changes and provide objective imaging markers for clinical evaluation.
		370-01-004. Shifting Brain Networks during pain processing and rest with Antibody Therapy in Ulcerative Colitis Responders Silke Kreitz, Kim Kaszuba, Raja Atreja, Arnd Dörfler, Andreas Hess Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany Impact: fMRI shows antibody therapy modulates ulcerative colitis brain function, but only in responders—defined by reduced symptoms (pain, fatigue, stool) at one month. Successful treatment altered pain processing and resting-state connectivity, suggesting brain markers for therapeutic success.
		370-01-005. Functional reorganization of lingual gyrus attenuates cognitive impairment in COPD: a multimodal neuroimaging study Qian Chen Beijing freindship hospital, Capital Medical University, Beijing, China
		370-01-006. Differentiation of Anti-NMDAR Encephalitis and Limbic Encephalitis Using Multiparametric MRI Histogram Analysis Jinglan Wang, Li Wu, Qiu Bi, Wei Sheng, Meining Chen The First Affiliated Hospital of Kunming Medical University, Kunming, China Impact: Multi-parameter MRI histogram parameters show promise as imaging biomarkers for distinguishing anti-NMDAR encephalitis from LE. When combined with clinical features, they improve early differentiation, refine subtype classification, and support personalized disease management.
		370-01-007. Deep Learning-Accelerated versus Standard Contrast-enhanced 3D FSE T1-Weighted Imaging for Detecting Acute Optic Neuritis Renjie Yang, Ying Liu, Weiyin Vivian Liu, Changsheng Liu, Liang Li, Yunfei Zha Renmin Hospital of Wuhan University, Wuhan 430060,China, Wuhan, China Impact: Sonic DL accelerates contrast-enhanced 3D FSE T1WI for optic neuritis diagnosis, improving efficiency without compromising quality. It enhances the visualization of inflammatory lesions, provides reliable measurements, and may improve longitudinal monitoring and clinical workflows in neuroradiology.
		370-01-008. Multiparametric qMRI mapping of myelin dynamics in multiple sclerosis: link with brain atrophy and disability progression Sara Alampi, Giordano Gentile, Alessandro Cagol, Ludovico Luchetti, Mario Ocampo-Pineda, Giuseppe Battaglia, Alessia Bianchi, Valentina Damato, Ludwig Kappos, Cristina Granziera, Nicola De Stefano, Rosa Cortese, Marco Battaglini University of Siena, Siena, Italy Impact: In multiple sclerosis brain white matter lesions, higher remyelination proportions were associated with slower brain atrophy and reduced disability progression, providing crucial insights into the relationships between remyelination and disease progression.
		370-01-009. Detecting early myelin damage linked to cognitive impairment before multiple sclerosis diagnosis Olivia Kalau, Sarah Morrow, Poljanka Johnson, Irene Vavasour, Cornelia Laule, Roger Tam, Jeffrey Wilken, Larry Lynd, Scott Patten, Yunyan Zhang, Alexandre Prat, Alan Wilman, Jiwon Oh, Anthony Traboulsee, Shannon Kolind University of British Columbia, Vancouver, Canada Impact: Myelin water imaging (MWI) can detect normal appearing white matter myelin damage in radiologically isolated syndrome, preceding diagnosis of multiple sclerosis, and relates to early cognitive changes. Thus, MWI provides a powerful early biomarker for potentially treatable damage.