Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

fMRI: Applications in Neurology and Psychiatry I

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fMRI: Applications in Neurology and Psychiatry I
Digital Poster
Brain Function & fMRI
Thursday, 14 May 2026
Digital Posters Row F
08:30 - 09:25
Session Number: 665-01
No CME/CE Credit
This session will cover the fMRI application to neurological disorders.

  Figure 665-01-001.  Hyper-reactivity to olfactory stimulation in the olfactory bulb in early Parkinson’s disease patients
Yu Luo, Jasper Duan, Kacie Cheng, Christopher Chen, Kevin Teng, Xinyi Zhou, Yuanqi Sun, Yuhan Bian, Adrian Paez, Liana Rosenthal, Alexander Pantelyat, Vidyulata Kamath, Jun Hua
Johns Hopkins University School of Medicine, Baltimore, United States of America
Impact: Loss of smell often occurs in Parkinson’s disease (PD). This study shows fMRI signals changes measured from early PD patients. Using advanced fMRI, this is a first study to show disease-related fMRI changes in the human olfactory bulb in vivo.
  Figure 665-01-002.  Track-weighted Dynamic Functional Connectivity Unravels the Structural-Functional Coupling in Treated Glioma Survivors
Joppe Van Rumst, Rob Colaes, Laurien De Roeck, Charlotte Sleurs, Sabine Deprez, Daan Christiaens, Stefan Sunaert, Maarten Lambrecht, Ahmed Radwan
KU Leuven, Leuven, Belgium
Impact: This study demonstrates that integrating structural and functional connectivity reveals tumor/treatment-related brain network disruptions in glioma survivors. This integration offers novel insights into the neural mechanisms of cognitive deficits, potentially providing novel regions to spare during radiotherapy, mitigating cognitive decline.
  Figure 665-01-003.  Cerebrovascular Reactivity in Parkinson’s Disease and Its Association With Hoehn and Yahr Stage
Jiajue Jiang, Yueluan Jiang, Zixuan Lin, Boyu Chen
The First Hospital of China Medical University, Shenyang, China
Impact: This study demonstrates the potential of resting-state fMRI–based cerebrovascular reactivity (rs-fMRI CVR) mapping as a noninvasive tool for detecting vascular dysfunction and disease progression in Parkinson’s disease.
  Figure 665-01-004.  Relationships between altered brain activity, childhood trauma, neurotransmitter, and genetic traits in gender dysphoria
Ruoyi Chen, Guanmao Chen, wei cui, Ying Wang
The First Affiliated Hospital of Jinan University, Guangzhou, China
Impact: From a clinical perspective, these findings highlight childhood trauma as an important component of an early intervention strategy to alleviate the psychological and emotional difficulties of TW individuals.
  Figure 665-01-005.  Differential Changes in Short- and Long-Range Brain Temporal Dynamics after Partial Sleep Deprivation
Fan Yang, Siqi Cai, Chunxiang Jiang, Lijuan Zhang
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
Impact: Partial sleep deprivation (PSD) leads to concurrent elevation of Hurst exponent and intrinsic neural timescale with differential distributions, indicating a shared susceptibility and heterogeneous response of the brain dynamics in balancing flexibility and stability following PSD.
  Figure 665-01-006.  The potential of neuroimaging to enhance the optimization of personalized tDCS interventions for aphasia rehabilitation
Venkatagiri Krishnamurthy, Elizabeth Tibus, Maryanne Weatherill, Amy Rodriguez, Josseirys Valentin Rivera, Bruce Crosson, Lisa Krishnamurthy
Emory University School of Medicine, Atlanta, United States of America
Impact: Implementing intensive speech-therapies for aphasia can be challenging in clinical settings. Neuromodulation techniques, such as tDCS, may not only help reduce treatment duration but also be cost-efficient, particularly when the optimization of tDCS can be personalized using simple neuroimaging techniques.
  Figure 665-01-007.  Structural and Functional Alterations in Sensory Motor Networks in Breast Cancer Patients Undergoing Treatments
Leonardo Tang, Quanquan Gu, Claire Gong, Nilo Vafaie, Tianhe Wu, Philip Kragel, Jinbing Bai, Hui Mao
Emory University School of Medicine, Atlanta, United States of America
Impact: The findings of this study not only strengthen the role of MRI biomarkers in cancer-related cognitive impairment but also reveal functional alterations in sensorimotor regions, offering new insights for development of targeted neurorehabilitation strategies to address previously overlooked sensorimotor deficits.
  Figure 665-01-008.  Hippocampal functional radiomics features for diagnosing cognitively impaired patients with Parkinson's disease
Zeng Wei, Xiao Liang, Jiankun Dai, Fuqing Zhou
The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China
Impact: Our study showed hippocampal radiomics features derived from rs-fMRI indices could distinguish cognitively impaired from cognitively preserved Parkinson's disease (PD). Therefore, rs-fMRI may be use as a non-invasive tool to provide objective and accuracy diagnosis of cognitively impaired PD patients.
  Figure 665-01-009.  Decoding Network-Level Reorganization in Sudden Sensorineural Hearing Loss: A Multilevel Functional Connectivity MRI Study
Wenliang Fan
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Impact: This study provides a multilevel connectomic framework revealing widespread network reorganization in SSNHL. The results highlight disrupted sensory–attention interactions and compensatory connectivity changes, offering neuroimaging biomarkers that may guide clinical evaluation and rehabilitation strategies for sudden hearing loss.
  Figure 665-01-010.  Age-related functional network alterations and molecular signatures in attention-deficit/hyperactivity disorder
Haoran Li, Xinyi Chen, Fei li
Huaxi MR Research Center (HMRRC), Institution of Radiology and Medical Imaging, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, P.R. China., Chengdu, China
Impact: This study reveals age-dependent functional connectivity alterations in ADHD centered on a subcortical-insula-DMN circuit across different large-scale networks, anchored in transcriptomic and neurotransmitter mechanisms that link functional network reorganization to neurodevelopmental differences.
  Figure 665-01-011.  fMRI guided Neuromodulation - A Predictive model in Stroke Upper limb Rehabilitation
ASHU BHASIN, Sparsh Singh, Gulafshan Iqbal, Vishnu VY, S Senthil Kumaran, M V Padma Srivastava
All India Institute of Medical Sciences, New Delhi, India
Impact: Combining tDCS with fMRI would help develop personalised tDCS protocols tailored for each patient. The stimulation-induced changes in the mechanisms of motor recovery, functional gains, and quality of life has an impact for stroke survivors.
  Figure 665-01-012.  Delayed Changes in Posterior Visual and Insula-Frontal Connectivity on Buprenorphine Maintenance Revealed by Dynamic ICA.
Nisha Chauhan, Anju Dhawan, Biswadip Chatterjee, Siddharth Sarkar, Mani Kalaivani, S Senthil Kumaran
All India Institute of Medical Sciences, New Delhi, India
Impact: Using Dynamic ICA, this study reveals delayed shifts in connectivity from posterior visual to insula-frontal control circuits during buprenorphine maintenance, highlighting the need for extended follow-up and future work linking delayed neural reorganization with clinical outcomes and recovery trajectories.
  Figure 665-01-013.  Identifying Risk Factors for Cancer-Related Cognitive Decline using Multimodal MRI
Rob Colaes, Gwen Schroyen, Ahmed Radwan, Rebeca Alejandra Gavrila Laic, Charlotte Sleurs, Shannon Helsper, Uwe Himmelreich, Sigrid Hatse, Ann Smeets, Sabine Deprez, Stefan Sunaert
KU Leuven, Leuven, Belgium
Impact: This study demonstrates the potential of integrating multimodal MRI with machine learning to predict cognitive decline in patients with breast cancer, supporting clinicians in early identification of high-risk individuals and initiating timely interventions to mitigate cognitive decline.
  Figure 665-01-014.  MRI in Clinical Practice: Dimensionality reduction and Machine-Learning decipheress therapy response in multi-parametric MRI
Mageshwar Selvakumar, Koray Tascilar, Arnd Dörfler, Georg Schett, Jürgen Rech, Andreas Hess
Friedrich Alexander University, Erlangen, Germany
Impact: We identified high baseline fMRI during painful joint compression as a powerful biomarker to predict TNFi response in RA. Our novel, cross-validated ML framework achieved 95% accuracy, confirming fMRI as the unique predictor, paving the way for personalized RA therapy.

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