Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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665-01-001.
Hyper-reactivity to olfactory stimulation in the olfactory bulb in early Parkinson’s disease patients
Impact: Loss of smell often occurs in Parkinson’s disease (PD). This study
shows fMRI signals changes measured from early PD patients. Using advanced fMRI,
this is a first study to show disease-related fMRI changes in the human
olfactory bulb in vivo.
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665-01-002.
Track-weighted Dynamic Functional Connectivity Unravels the Structural-Functional Coupling in Treated Glioma Survivors
Impact: This study demonstrates that
integrating structural and functional connectivity reveals tumor/treatment-related brain network disruptions in glioma survivors. This integration offers novel
insights into the neural mechanisms of cognitive deficits, potentially
providing novel regions to spare during radiotherapy, mitigating cognitive
decline.
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665-01-003.
Cerebrovascular Reactivity in Parkinson’s Disease and Its Association With Hoehn and Yahr Stage
Impact: This
study demonstrates the potential of resting-state fMRI–based cerebrovascular
reactivity (rs-fMRI CVR) mapping as a noninvasive tool for
detecting vascular dysfunction and disease progression in Parkinson’s disease.
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665-01-004.
Relationships between altered brain activity, childhood trauma, neurotransmitter, and genetic traits in gender dysphoria
Impact: From a clinical perspective, these findings highlight childhood trauma as an important component of an early intervention strategy to alleviate the psychological and emotional difficulties of TW individuals.
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665-01-005.
Differential Changes in Short- and Long-Range Brain Temporal Dynamics after Partial Sleep Deprivation
Impact: Partial sleep deprivation (PSD) leads to concurrent elevation of Hurst exponent and intrinsic neural timescale with differential distributions, indicating a shared susceptibility and heterogeneous response of the brain dynamics in balancing flexibility and stability following PSD.
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665-01-006.
The potential of neuroimaging to enhance the optimization of personalized tDCS interventions for aphasia rehabilitation
Impact: Implementing intensive speech-therapies
for aphasia can be challenging in clinical settings. Neuromodulation
techniques, such as tDCS, may not only help reduce treatment duration but also
be cost-efficient, particularly when the optimization of tDCS can be
personalized using simple neuroimaging techniques.
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665-01-007.
Structural and Functional Alterations in Sensory Motor Networks in Breast Cancer Patients Undergoing Treatments
Impact: The findings of this study not only strengthen the role of MRI biomarkers in cancer-related cognitive impairment but also reveal functional alterations in sensorimotor regions, offering new insights for development of targeted neurorehabilitation strategies to address previously overlooked sensorimotor deficits.
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665-01-008.
Hippocampal functional radiomics features for diagnosing cognitively impaired patients with Parkinson's disease
Impact: Our study showed hippocampal radiomics features derived from rs-fMRI indices could distinguish cognitively impaired from cognitively preserved Parkinson's disease (PD). Therefore, rs-fMRI may be use as a non-invasive tool to provide objective and accuracy diagnosis of cognitively impaired PD patients.
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665-01-009.
Decoding Network-Level Reorganization in Sudden Sensorineural Hearing Loss: A Multilevel Functional Connectivity MRI Study
Impact: This study provides a multilevel connectomic framework revealing widespread network reorganization in SSNHL. The results highlight disrupted sensory–attention interactions and compensatory connectivity changes, offering neuroimaging biomarkers that may guide clinical evaluation and rehabilitation strategies for sudden hearing loss.
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665-01-010.
Age-related functional network alterations and molecular signatures in attention-deficit/hyperactivity disorder
Impact: This study reveals age-dependent functional connectivity alterations in ADHD centered on a subcortical-insula-DMN circuit across different large-scale networks, anchored in transcriptomic and neurotransmitter mechanisms that link functional network reorganization to neurodevelopmental differences.
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665-01-011.
fMRI guided Neuromodulation - A Predictive model in Stroke Upper limb Rehabilitation
Impact: Combining tDCS with fMRI would help develop personalised
tDCS protocols tailored for each patient. The stimulation-induced changes in
the mechanisms of motor recovery, functional gains, and quality of life has an
impact for stroke survivors.
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665-01-012.
Delayed Changes in Posterior Visual and Insula-Frontal Connectivity on Buprenorphine Maintenance Revealed by Dynamic ICA.
Impact: Using Dynamic ICA, this study reveals delayed shifts
in connectivity from posterior visual to insula-frontal control circuits during
buprenorphine maintenance, highlighting the need for extended follow-up and future
work linking delayed neural reorganization with clinical outcomes and recovery
trajectories.
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665-01-013.
Identifying Risk Factors for Cancer-Related Cognitive Decline using Multimodal MRI
Impact: This study demonstrates the potential of integrating multimodal MRI with machine learning to predict cognitive decline in patients with breast cancer, supporting clinicians in early identification of high-risk individuals and initiating timely interventions to mitigate cognitive decline.
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665-01-014.
MRI in Clinical Practice: Dimensionality reduction and Machine-Learning decipheress therapy response in multi-parametric MRI
Impact: We identified high baseline fMRI during painful joint
compression as a powerful biomarker to predict TNFi response in RA. Our novel,
cross-validated ML framework achieved 95% accuracy, confirming fMRI as the
unique predictor, paving the way for personalized RA therapy.
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© 2026 International Society for Magnetic Resonance in Medicine