Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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570-09-230.
Multiexponential contributions in T1xT2 relaxometry
Impact: By jointly sampling T₁
and T₂ relaxation, 2D-T₁×T₂ MRI can disentangle multiple tissue components
within a voxel. This multidimensional relaxometry framework may help better
understand and model the biological source of MRI signals.
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570-09-231.
Magnetization-transfer manipulation reveals relaxometry bias
Impact: Magnetization transfer
significantly biases conventional T₁ relaxometry. Here we causally show the
effect of MT on T1 quantification. By explicitly modeling MT alongside T₁ and
T₂ within a unified framework, our simulations show improved quantification accuracy.
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570-09-232.
Simultaneous T1, T2 mapping of the Lung at 0.55T: A Free-Breathing and Automated Approach
Impact: The proposed
method for lung relaxometry successfully eliminates the need for breath-holding
and ECG-gating, thereby making it not only more viable for clinical use but
also more robust.
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570-09-233.
Feasibility of 3D water T1 and T2 mapping for pulmonary lesion assessment
Impact: Simultaneous T1/T2 mapping with a T2-prepared Look-Locker Cartesian acquisition with spiral profile ordering enables 3D lung quantification within reasonable scan times (∼7min) and anatomically sufficient slice thickness (2.5mm). Quantification of pulmonary nodules may allow earlier differentiation beyond morphological assessment.
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570-09-234.
Whole brain T1, T2, PD & T2* quantification in 5 minutes with multi-echo MR-STAT
Impact: The MR-STAT framework is extended to generate
T1,T2,T2*,PD,SWI,T2w,T1w,FLAIR images from a single 5 minute scan. This short,
comprehensive protocol will reduce scan time pressure and facilitate
multi-parametric assessment in clinical practice.
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570-09-235.
Variable flip angle chemical-shift encoded (VFA-CSE) MRI in quantitative whole-body imaging of malignant bone disease
Impact: Variable flip angle chemical-shift encoded (VFA-CSE) MRI enables
simultaneous morphological T1-weighted imaging with fat fraction, T1, and R2*
quantification, accounting for biases in routine T1-weighted 2-point Dixon
imaging recommended in international guidelines for whole-body metastatic
prostate cancer and myeloma assessment.
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570-09-236.
3D Brain MR Elastography with 1mm isotropic resolution at 3T
Impact: 3D-EPI–based MR elastography enables high
spatial resolution for assessing whole cerebral biomechanical properties in-vivo with phase signal consistency in 3D, benefiting research on local lesion
characterization and pathologies with whole brain involvement.
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570-09-237.
3D Quantification of Oxygen Extraction Fraction in the Medial Temporal Lobe Using Implicit Neural Representation
Impact: We achieved
accurate 3D quantification of oxygen extraction fraction (OEF) in the medial
temporal lobe (MTL) in 3.2 minutes, facilitating future investigations of OEF
as a biomarker for MTL-related brain disorders such as Alzheimer’s disease.
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570-09-238.
MREPT-derived conductivity as a quantitative and complementary biomarker of white matter hyperintensity to FLAIR
Impact: Conductivity distinguishes WMHs from normal white matter and
retains dynamic range where FLAIR saturates, offering a potential quantitative
biomarker of lesion severity.
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© 2026 International Society for Magnetic Resonance in Medicine