Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition - Quantitative Imaging: Multiparametric and Synthetic MRI

Quantitative Imaging: Multiparametric and Synthetic MRI

Oral

Acquisition & Reconstruction

Thursday, 14 May 2026

Meeting Room 1.60

16:00 - 17:50

Moderators: Nirbhay Yadav & David Porter

Session Number: 608-03

CME/CE Credit Available

Similar Sessions

This session provides an overview of new methods and applications in quantitative and synthetic MR imaging.

Skill Level: Intermediate,Advanced

16:00		608-03-001. A Travelling Kidney and Repeatability Study using the harmonised UKRIN-MAPS multiparametric renal MRI protocol Charlotte Buchanan, Hao Li, Alexander Daniel, Martin Craig, Kevin Teh, Iosif Mendichovszky, David Thomas, Steven Sourbron, Andrew Priest, Susan Francis University of Nottingham, Nottingham, United Kingdom Impact: Harmonisation and standardisation is crucial for multi-centre evaluation and clinical translation of renal MRI measures. We demonstrated the UKRIN-MAPS acquisition and analysis pipeline provides good inter- and intra-session CV, essential for the interpretation of future multi-centre trials in kidney disease.
16:11		608-03-002. High-resolution highly accelerated free breathing 3D joint T1/T2 and PDFF/T2* mapping of the liver at 0.55T Felipe Ercoli, Dongyue Si, Michael Crabb, Nicolas Garrido, Diego Pedraza, Karl Kunze, Claudia Prieto, Rene Botnar Millennium Institute for Intelligent Healthcare Engineering - iHEALTH, Santiago, Chile Impact: High-resolution free breathing 3D joint T1/T2 and 3D joint PDFF/T2* mapping of the entire liver is feasible with two 3D acquisitions in a total scan time of ~9 min at 0.55T enabling more affordable and comprehensive assessment of liver disease.
16:22		608-03-003. Efficacy of Single Breath-hold Multi-echo 3D-QALAS for Robust Quantitative Abdominal MRI Nader Metwalli, Ronald Ouwerkerk, Deneshree Padayachee, Jonathan Dillman, Ahmed Gharib National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, United States of America Impact: Single breath-hold multi-echo 3D-QALAS synthetic T1, T2, T2*, and fat fraction parametric maps in abdominal MRI are not interchangeable with their conventional parametric sequence counterparts except for PDFF from Dixon. Sequence timings need optimization to capture wider tissue relaxation times.
16:33		608-03-004. Multiparametric qMRI of Peripheral Nerves: Diagnostic Differentiation and Biomarker Development in Polyneuropathies Jesus Fajardo, Vivian Truong, Yang Xuan, Sara Benitez, Mary Vo, Bo Hu, Richard Dortch , Jun Li, Yongsheng Chen Wayne State University School of Medicine, Detroit, United States of America Impact: Multiparametric qMRI of proximal nerves reliably differentiates between demyelinating and axonal polyneuropathies, which could complement nerve conduction studies on distal nerves for diagnosis. The composite qMRI score could be a non-invasive biomarker candidate for monitoring disease progression.
16:44		608-03-005. T1 and T2 mapping of the human brain across magnetic field strengths from 0.047 T to 7.0 T Martijn Nagtegaal, Navid Jabarimani, Yiming Dong, Ece Ercan, Jan Groen, Matthias van Osch, Andrew Webb, Chloe Najac Leiden University Medical Center, Leiden, Netherlands Impact: Measuring T₁ and T₂ in the same subjects from 0.047T to 7.0T on the same software allows more rigorous determination of the dependency on field strengths, which in turn aids in contrast optimization for mid- and low-field MRI.
16:55		608-03-006. MWF-MIMOSA for Highly-efficient Joint Relaxometry and Myelin Water Fraction Mapping Yuting Chen, Yohan Jun, Hyeong-Geol Shin, Shizhuo Li, Shohei Fujita, Xingwang Yong, Jiye Kim, Jongho Lee, Gian Franco Piredda, Tom Hilbert, Huafeng Liu, Huihui Ye, Borjan Gagoski, Kwok-Shing Chan, Berkin Bilgic College of Optical Science and Engineering, Zhejiang University, Hangzhou, China Impact: MWF-MIMOSA enables whole-brain T₁, T₂, T₂^*, PD, QSM, susceptibility source separation, and MWF mapping at 1 mm³ resolution in 5 minutes, achieving simultaneous relaxometry and myelin water fraction mapping in a single scan for comprehensive tissue characterization.
17:06		608-03-007. Whole-Brain Mapping of Formaldehyde Fixation Using Multiparametric MRI Chenyang Li, Huize Pang, Tianyu Gao, Rohit Jena, Dominique Leitner, Thomas Wisniewski, Arline Faustin, Henrieta Scholtzova, Laura Gould, Orrin Devinsky, James Gee, Youssef Wadghiri, Jiangyang Zhang, Yulin Ge NYU Grossman School of Medicine, New York, United States of America Impact: Multiparametric MRI enables whole-brain tracking of spatially heterogeneous formaldehyde fixation in postmortem tissue. Validated by gross dissection of brain specimen, T1-based measures are most sensitive to different fixation stages, which can non-invasively monitor fixation progression before dissection or histological sampling.
17:17		608-03-008. Clinical Acquisition of Joint T1-T2 Contrast-Encoded MRI at 0.064T Ella Wilczynski, Alexandru Avram, Kulam Najmudeen Magdoom, Nathan Williamson, Silvina Horovitz , Peter Basser Eunice Kennedy Shriver - National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, United States of America Impact: Achieving joint T₁–T₂ encoding in vivo at 64 mT establishes a foundation for future multi-dimensional MRI studies on portable low-field scanners. This capability enables new scientific questions about tissue composition and supports wider deployment of quantitative imaging in resource-limited environments.
17:28		608-03-009. Resolving and Quantifying Subvoxel Tissue Components in Multidimensional MRI for Clinical Translation Alexandru Avram, Kulam Najmudeen Magdoom, Ella Wilczynski, Peter Basser Eunice Kennedy Shriver - National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, United States of America Impact: By disentangling signals from subvoxel tissue components with distinct MR-relaxation and diffusion properties, we enable more specific and reproducible quantitative imaging biomarkers. This approach can improve clinical diagnostic sensitivity and open new avenues for investigating tissue heterogeneity and microstructural pathology.
17:39		608-03-010. Dipolar order mapping based on spin-lock magnetic resonance imaging Zijian GAO, Qianxue Shan, Ziqin Zhou, Ziqiang Yu, Weitian Chen The Chinese University of Hong Kong, Hong Kong, China Impact: We propose a spin-lock MRI method for T_1D quantification, providing a sensitive assessment of myelin microstructural integrity. It has the potential to improve understanding of myelin-related mechanisms and serve as a biomarker for neuroprotection and repair in clinical trials.