Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition - Perfusion, Flow, and Hemodynamics Across Scales

Perfusion, Flow, and Hemodynamics Across Scales

Oral

Contrast Mechanisms

Thursday, 14 May 2026

Ballroom East

13:40 - 15:30

Moderators: Xingfeng Shao & Lirong Yan

Session Number: 604-02

CME/CE Credit Available

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This session highlights recent advances in MRI methods for imaging perfusion, flow, and hemodynamics across organs and applications.

Skill Level: Advanced

13:40		604-02-001. A flow-diffusion model of capillary oxygen transport for the estimation of venous cerebral blood volume from GE-SE signal Stefano Zappalà, Eleonora Patitucci, James Powell, Sahar Iqbal, Fabian Küppers, N. Jon Shah, Richard Wise, Michael Germuska Cardiff University, Cardiff, United Kingdom Impact: The flow-diffusion model can stabilize estimations of cerebral blood volume derived directly from GE-SE EPIK MR signal decay. This sub-7-minute, non-invasive approach delivers accurate oxygenation measurements in both healthy and tumour tissue, with a clear potential for clinical translation.
13:51		604-02-002. Cerebral hemodynamics in white matter lesions and their penumbra in older adults using 7T arterial spin labeling MRI Jan Kufer, Hannah Weibley, Theodora Martin, Marta Vidorreta, John Detre, Yulin Chang, Jason Stockmann, Meher Juttukonda Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America Impact: Our results suggest that applications of optimized 7T ASL to investigate white matter hemodynamics in older adults are feasible.
14:02		604-02-003. KIVA: Water Exchange Rate (kw) Imaging with Velocity-selective Arterial Spin Labeling Chenyang Zhao, Asmit Ganguly, Ziyang Huang, Tanxin Dong, Zidong Yang, Xingfeng Shao, Danny Wang University of Southern California, Los Angeles, United States of America Impact: This work enables arterial spin labeling to quantify blood–brain barrier water exchange without transit-time confounds, allowing faster, more reliable assessment of BBB function.
14:13		604-02-004. Microvascular velocity and deceleration imaging using multi-velocity-encoding multi-delay arterial spin labeling Shota Ishida, Yuki Matta, Makoto Isozaki, Yu Ueda, Makoto Obara, Yasuhiro Fujiwara, Tetsuya Tsujikawa Kyoto University of Medical Science, Nantan, Japan Impact: Multi-velocity-encoding, multi-delay arterial spin labeling using an extended multiparametric framework quantifies microvascular velocity and deceleration without compromising cerebral blood flow or arterial cerebral blood volume measures. These metrics are potentially more sensitive to neurovascular pathology than conventional perfusion measures.
14:24		604-02-005. QQ-F: A Generalized QQ-based Deep Learning Approach for Oxygen Extraction Fraction Mapping across Diverse Acquisition Schemes Tian Qiu, Ada ally, Arpita Misra, Gloria Chiang, Thanh Nguyen, Susan Gauthier, Shun Zhang, Yi Wang, Junghun Cho George Washington University, Washington, United States of America Impact: Our proposed deep learning approach, QQ-F, eliminates the need for retraining across different measurement sampling schemes. QQ-F enables widely applicable OEF mapping in clinical settings through its ability to process a single routine MR dataset acquired with any sampling scheme.
14:35		604-02-006. CSF or tissue: which one is the most important to suppress as background signal in ASL? Zhiyi Hu, Wen Shi, Yifan Gou, Zihan Wang, Vivek Yedavalli, Doris Lin, Hanzhang Lu Johns Hopkins University School of Medicine, Baltimore, United States of America Impact: CSF pulsation is identified as the leading source of noise in ASL. The proposed CSF BS approach can be readily integrated into clinical ASL protocols and may enhance the reliability of perfusion imaging in both research and clinical settings.
14:46		604-02-007. Influence of pCASL labeling duration on blood-to-CSF water exchange measurements: better SNR and proof of direct exchange Helena Durrant, Nina Fultz, Emiel Roefs, Lydiane Hirschler, Matthias van Osch, Lena Vaclavu C.J. Gorter MRI Center, Leiden University Medical Center, Netherlands Impact: This work suggests that extended labeling durations offer enhanced sensitivity for ASL-based measurements of blood-to-CSF water exchange. Moreover, the findings shed light on the routes of water transport, supporting the interpretation of a direct blood-to-CSF pathway.
14:57		604-02-008. High-resolution 3D Manganese-enhanced MRI for the Detection of Viable Myocardium in a Post-Infarct Sheep Model Alexis Rotondi, Julie Magat, Fanny Vaillant, Nestor Pallares-Lupon, Richard Walton, Olivier Bernus, bruno Quesson Univ. Bordeaux, Bordeaux, France Impact: High-resolution MEMRI enables non-invasive detection of viable myocardium within post-infarct scars, improving risk assessment arrhythmia without requiring invasive contact catheter mapping. This technique can guide targeted therapies and unlock research into arrhythmogenic substrates previously inaccessible with conventional LGE imaging methods.
15:08		604-02-009. Peri-nidal Hypoperfusion on Multi-Delay ASL Is Associated with Epilepsy in Unruptured Brain Arteriovenous Malformation Xiaoqian Li, Chunxue Wu, Yayan Yin, Boyan Xu, Tao Wu, Qin Qin, Jie Lu Xuanwu Hospital, Capital Medical University, Beijing, China Impact: This study indicates that multi-delay ASL can visualize the steal phenomenon in peri-nidal area of AVM-related epilepsy, potentially enabling intervention monitoring and personalized management. It offers a non-invasive tool for prognosis and optimizing treatment timing.
15:19		604-02-010. Arterial Spin Labeling MRI for Bladder Cancer: Correlation with Histopathology and Comparison with DCE-MRI Erjia Guo, Li Chen, Gumuyang Zhang, Zhengyu Jing, Hao Sun, Jinxia ZHU, Bernd Kuehn Peking Union Medical College Hospital, Beijing, China Impact: Non-invasive and quantitative arterial spin labeling is a valuable technique for bladder cancer evaluation by providing tumor perfusion that reflects tumor aggressiveness, while achieving comparable performance to DCE-MRI for detecting muscle-invasive bladder cancer.