Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition - New Outcome Measures for Studying the Joint

New Outcome Measures for Studying the Joint

Oral

Musculoskeletal

Tuesday, 12 May 2026

Meeting Room 1.40

16:00 - 17:50

Moderators: Casey Johnson

Session Number: 407-04

No CME/CE Credit

Similar Sessions

Methods for studying tissue microstructure, composition, shape and function in the joint beyond cartilage

16:00		407-04-001. The Impact of Age, Sex, BMI, and OA Status on Meniscus UTE-T2* Relaxation Times and Volumes Ananya Goyal, Yael Vainberg, Rachel Shalit, Feliks Kogan Stanford University, Stanford, United States of America Impact: Quantitative UTE-T2* mapping sensitively detects meniscal microstructural changes associated with aging, sex, and osteoarthritis. These findings show the utility of UTE-T2* as a noninvasive biomarker of early joint degeneration, enabling improved detection and monitoring of meniscal health in osteoarthritis.
16:11		407-04-002. 3D T2* Mapping Detects Persistent Meniscal Collagen Disorganization and Extrusion After Medial Meniscus Posterior Root Tear Abdul Wahed Kajabi, Karsten Knutsen, Eisa Hedayati, Collin Steinberger, Abhinav Lamba, Stefan Zbyn, Asif Abul Hassan, Hassan Ahad, Luke Tollefson, Takashi Takahashi, Gregory Metzger, Rob LaPrade, Jutta Ellermann Center for Magnetic Resonance Research, Dept. of Radiology, University of Minnesota, Minneapolis, United States of America Impact: Persistently elevated T2* values after medial meniscus root repair and their correlation with postoperative meniscal extrusion suggest delayed restoration of the collagen fiber network, highlighting the need for precise monitoring of healing and tailored surgical interventions to mitigate the extrusion.
16:22		407-04-003. Linking Neuronal Activity with Cartilage Degeneration in Early Knee Osteoarthritis: Comparison with T1ρ Mapping Anmol Monga, Hector Lise de Moura, Yongxian Qian, Jonathan Samuels, Ravinder Regatte NYU Grossman School of Medicine, New York, United States of America Impact: Quantum-sensing MRI allows noninvasive detection of neuronal firing associated with cartilage degeneration and pain in knee osteoarthritis, highlighting its potential as a biomarker for early diagnosis, objective pain assessment, and therapy monitoring.
16:33		407-04-004. Normative quantitative UTE MRI of the anterior cruciate ligament at 3 T: demographic stability across 56 healthy knees. Maik Rothe, Richard Brill, Walter Wohlgemuth, Alexander Gussew Medical Physics Group, University Clinic and Outpatient Clinic for Radiology, University Hospital Halle (Saale), Germany Impact: This study establishes robust normative UTE-derived ACL biomarkers, demonstrating demographic stability across age and sex and introducing an effect-size–based framework that strengthens quantitative study design and enables early, reliable differentiation between physiological and pathological ligament changes.
16:44		407-04-005. Increased Frequency of High-Intensity Physical Activity Associates with OA-like Changes to Femoral Bone Shape Following ACLR Ashley Williams, Anthony Gatti, Anoosha Pai S, Jade He, Constance Chu Stanford Medicine, Stanford, United States of America Impact: Neural shape modeling-based bone shape scores suggest that frequently engaging in high-intensity physical activities within the first 2 years following ACL reconstruction may have negative consequences for bone shape remodeling leading to development of osteoarthritis-like bone shape features.
16:55		407-04-006. Semiquantitative MRI scores and CNR correlate with bone quality (histology and micro-CT) after osteochondral implantation Felix Merlin König, Veronika Janacova, Markus Schreiner, Marlene Stuempflen, Vladimir Juras, Pavol Szomolanyi, Janina Patsch, Giuseppe Filardo, Ali Guermazi, Siegfried Trattnig Medical University of Vienna, Vienna, Austria Impact: By demonstrating strong correlations between MRI signal intensity and bone regeneration metrics, this study highlights MRI as a novel, radiation-free, non-invasive method for evaluating bone healing post-implantation, potentially enhancing patient monitoring and improving outcomes in both research and clinical care
17:06		407-04-007. Quantitative Assessment of the Infrapatellar Fat Pad after ACLR Based on mDIXON-Quant Technology Chenxi Huang, Jinze Dong, Zhongyan Xu, Yiou Wang, Qinglin Xie, youbin Ding, Zhongping Zhang, Peng Wu, Xiaodong Zhang The First Clinical Medical School of Southern Medical University, Guangzhou, China Impact: The mDIXON-Quant technique not only provides a novel quantitative tool for assessing IFP after ACLR but also offers a scientific basis for a deeper understanding of postoperative pathological changes and their relationship with functional recovery.
17:17		407-04-008. Repeatability and Regional Variability of Knee Fatty Acid Composition from CSE-MRI at 3T Dimitri Martel, Anne Adlung, Guillaume Madelin, Thorsten Kirsch, Richard Kijowski, Amparo Ruiz New York University Langone Health, New York, United States of America Impact: CSE-MRI yields repeatable PDFF and fatty-acid composition maps in the knee, defining quantitative thresholds for measuring longitudinal changes. These benchmarks enable metabolic phenotyping of osteoarthritis beyond structure, supporting clinical trials targeting inflammation and lipid remodeling.
17:28		407-04-009. Quantification of Infrapatellar Fat Pad Fatty Acid Composition across ACLR and KOA Cohorts using CSE-MRI at 5T Siyi Wu, Luoyong Jiang, Chuanli Cheng, Luyao Ma, Hanyu YAO, Xin Gao, Chao Zou, Xin Liu, Hairong Zheng, Liwen Wan Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China Impact: Joint quantification of PDFF, FAC, and R2* of IPFP using CSE-MRI can reveal disease differences between KOA and ACLR, supporting their potential use as non-invasive biomarkers for prognosis, early surveillance, and personalized intervention.
17:39		407-04-010. Guided Discussion Casey Johnson University of Minnesota, Minneapolis, United States of America