Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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667-04-001.
Rapid Multiparametric UTE MRI for In Vivo Compositional Assessment of Human Bone
Impact: The
multiparametric UTE protocol quantifies major bone components in
vivo within a short scan time. This approach can provide a complete set of compositional information relevant to skeletal
fragility and metabolic dysfunction that are not captured by mineral density
alone.
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667-04-002.
Bone reporting and data system (Bone-RADS) on CT versus MRI: a multicenter comparison study by four readers on 122 cases
Impact: Bone-RADS-CT and Bone-RADS-MRI are effective tools with high sensitivities for identifying the bone lesions that need treatment, but both have disadvantages of low specificities that lead to unnecessary treatment or referral, and potential of conflicting results that confuse the clinicians.
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667-04-003.
Cortical Bone Matrix and Porosity Assessment in Osteoporosis and CKD-MBD Using Novel 3D UTE-MRI Biomarkers
Impact: UTE-MRI measurements detect cortical bone matrix
loss and porosity increase associated with osteoporosis and CKD-MBD, providing microstructural
information not captured by DXA alone. These markers may improve fracture-risk
assessment and monitor bone health in aging patients with metabolic bone
disorders.
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667-04-004.
Deep Learning Synthesis of Pseudo-CT from UTE-MRI for Temporal Bone Imaging
Impact: Radiation-free pseudo-CT synthesis from MRI offers safer temporal bone imaging, reducing dependence on CT while preserving diagnostic detail. Leading the way for MRI-only surgical planning and longitudinal follow-up.
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667-04-005.
Characterization of cortical bone relaxation times at low magnetic field
Impact: We validate UTE-2D acquisition at $0.55~\text{T}$, enabling low-field characterization of cortical bone relaxation processes and supporting accessible, quantitative evaluation of bone fragility and fracture risk.
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667-04-006.
Q-flow Assessment of Femoral Head Perfusion Impairment Following Femoral Neck Fractures
Impact: Q-flow enables noninvasive quantification of blood flow changes after femoral neck fractures, helping clinicians assess vascular injury and the risk of impaired femoral head perfusion. This approach may guide individualized treatment, and inspire future research on for osteonecrosis prediction.
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667-04-007.
Multimodal Imaging combined with finite element analysis to explore cortical bone microstructural damage in T1DM rabbits
Impact: Multimodal
imaging and finite element analysis revealed a progressive deterioration of increased
cortical porosity, stress concentration, and microdamage accumulation. These
findings provided a biomechanical basis for bone fragility in T1DM and
highlighted early fracture prevention targets.
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667-04-008.
Deep Learning-Based Background Removal in FRACTURE MRI
Impact: We present a deep learning model that removes
bright background from FRACTURE images with 99% accuracy, enhancing comparability to CT and X-ray. This advancement improves MR-based bone imaging
utility, moving toward MRI as a comprehensive, single-modality solution for
musculoskeletal diagnostics.
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667-04-009.
Efficient Diffusion-based Reconstruction for 3D Non-Cartesian UTE Imaging
Impact: We
present an efficient diffusion model for accelerated 3D radial UTE
reconstruction that delivers consistent image quality, while reducing inference
time by 75% compared to previous approaches, even outperforming unrolled
networks trained on the same data in image quality.
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667-04-010.
Ossification Variants and Juvenile Osteochondritis Dissecans May Represent a Developmental Spectrum: MRI Findings in Siblings
Impact: OV’s and JOCD occur more frequently in siblings of JOCD when compared to the baseline population. This combined with observing an OV developing into JOCD suggests these may be on a continuum of endochondral dysfunction rather than two distinct pathologies.
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667-04-011.
Combined Shape Modeling Approaches for Patellofemoral Instability
Impact: The stratification of shape, rotation, and
translation changes across subjects and between bones using statistical shape
models could lead to better characterization of musculoskeletal conditions such
as patellofemoral instability and ultimately to more targeted treatments.
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667-04-012.
Relationships between MRI-observed patellar motion and knee/limb tissue characteristics in hypermobile Ehlers-Danlos patients
Impact: The
results highlight the roles of the MPFL and PT in patellar kinematics and indicate
that T2*, which is known to correlate with tissue collagen
organization/content, may be a useful biomarker for altered collagen
properties/function in these structures.
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667-04-013.
Whole-Body Staging MRI Incidental Findings: Significance and Follow-up among different primary malignancies
Impact: WB-MRI in an oncologic patient population accurately
characterizes most visceral organ and osseous incidental findings. Only a
relatively small proportion of patients require immediate additional downstream
imaging or procedures, of which a substantial number are ultimately found to be
malignant/pre-malignant.
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667-04-014.
Prediction of Osteoporosis in Postmenopausal Women Using Disc Signal Intensity Index Combined with Intervertebral Disc Height
Impact: This study provided radiation-free MRI biomarkers combining disc signal and height to predict osteoporosis in postmenopausal women, enabling earlier detection and prevention of osteoporosis.
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667-04-015.
Improved SNR and Acceleration of 1.5T Spine Imaging by Combining Flexible Surface Coils with the Built-in Spine Coil
Impact: Combining
commercially available flexible coil arrays with the built-in spine coil within
the MR scanner table increases SNR and improves acceleration performance for
1.5T spine imaging without suffering image quality issues from channel coupling.
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