Quantitative Outcome Measures in MSK MRI
Digital Poster
Musculoskeletal
Wednesday, 13 May 2026
Novel quantitative outcome measures in musculoskeletal MRI
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566-06-001.
Preliminary Study on Analyzing Inflammatory Activity in axSpA Using DCE-MRI-Based Multiparametric Radiomics Models
Impact: This study introduces a quantitative imaging framework that
enhances diagnostic precision and clinical decision-making for axSpA. It may
guide personalized monitoring of inflammatory activity and stimulate further
research into radiomics-based assessment of musculoskeletal inflammation.
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566-06-002.
Accelerating T1ρ Knee Mapping via Jointly Learning Sampling and Deep Quantitative MRI
Impact: Joint learning enabled faster, model-consistent T1ρ mapping with improved fidelity from undersampled data, enhancing early OA detection. Direct mapping with machine-designed sampling patterns outperformed manual designs, advancing quantitative MRI toward practical deployment in musculoskeletal imaging.
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566-06-003.
Foot Perfusion Mapping Using 3D Stack-of-Spirals FLASH-based Velocity-Selective ASL: Development and Comparison with pCASL
Impact: The VSASL technique shows strong promise for
noninvasive quantification of microvascular perfusion in the foot, enabling
improved ischemia evaluation and potential clinical translation.
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566-06-004.
Longitudinally monitoring non-enzymatic crosslinking of collagen in bovine tendon via UTE quantitative MT (UTE-qMT) imaging
Impact: We demonstrate that collagen
crosslinking via advanced glycation endproducts in tendon can be monitored via
UTE-qMT MRI. This technique may advance our understanding of the pathology of
diabetic tendinopathy and expedite the development of targeted novel
treatments.
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566-06-005.
Sex-Specific Alterations in Thigh Muscle Quality in Individuals with Knee Osteoarthritis
Impact: This study gives us insight into the ways OA may affect muscle quality differently by sex, allowing for more targeted muscle strengthening that could lead to better prevention and alleviation of OA symptoms.
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566-06-006.
Quantitative muscle assessment in Parsonage-Turner Syndrome: A Prospective, Longitudinal Study
Impact: Muscle qMRI objectively characterizes muscle quality changes in PTS and can provide confirmatory evidence for muscle denervation to supplement the diagnosis of PTS. Muscle T2 can help inform PTS patients’ recovery of muscle strength.
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566-06-007.
Quantitative Assessment of Intramuscular Fibrosis Using UTE MRI in Sarcopenia and muscle aging
Impact: This study aims to overcome current
limitations in early sarcopenia diagnosis by developing UTE MRI–based tools to
quantify muscle fibrosis, a key feature of the disease, and to evaluate its
role in disease progression.
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566-06-008.
Evaluation of Arterial Spin Labeling Imaging Methods for Jaw Muscle Perfusion Imaging
Impact: Reliable and robust ASL imaging of jaw muscle is critical for the
investigation of the pathophysiological mechanisms of temporomandibular
disorders (TMDs) and to get insights into the potential jaw muscle
metabolic dysfunction and its relation to chronic TMD pain.
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566-06-009.
Comprehensive Deep-Learning-Based Assessment of Quantitative Magnetic Resonance Imaging in patients with Dystrophinopathies
Impact: Deep-learning-based
qMRI provides a noninvasive and reproducible method for comprehensive muscle
evaluation. It integrates multiple quantitative parameters. Offering an
objective biomarker for disease staging, treatment monitoring, and personalized
assessment in dystrophinopathies.
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566-06-010.
Automated Quadriceps Segmentation and Torque Prediction from Multi-Vendor MRI: Cross-Sectional Area vs. Radiomics
Impact: An automated pipeline converts routine Dixon MRI into useful strength indicators, providing quadriceps muscle segmentations across three MR vendors. Beyond CSA, radiomics captures compositional cues that improve muscle strength estimation, particularly in heterogeneous cohorts.
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566-06-011.
Determining the Repeatability and Precision of qDESS for Quantifying Muscle-Water T2 of Skeletal Muscle in FSHD
Impact: The 3D qDESS method produces robust and accurate $T_2$ maps of the lower limb with substantially shorter acquisition times than the MESE sequence, making it a viable tool for FSHD clinical trials.
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566-06-012.
Quantitative MRI of avascular necrosis: comparison between a piglet model and children with Legg-Calvé-Perthes disease
Impact: Our
study directly compared quantitative MRI measures in children with LCPD and in a
preclinical model used to inform pathogenesis and treatment this condition. We
identified specific similarities and differences between species that have
important implications for future study.
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566-06-013.
Radiomics-Integrated Dual-Encoder Attention Network for Automatic Thigh Muscle Segmentation in MRI
Impact: Integrating radiomics features with deep learning improved segmentation robustness and stability. This approach may facilitate more reliable and reproducible quantitative muscle analysis, contributing to objective assessment of neuromuscular disorders in both research and clinical applications.
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566-06-014.
Proton Density Fat Fraction in Bone Marrow and Muscle: Repeatability and Reproducibility Across Field Strength and Protocol
Impact: Establishing
PDFF as a reliable biomarker in skeletal muscle and bone marrow is necessary to
enable widespread adoption. High performance repeatability and
reproducibility is essential for multi-center studies and to accelerate its adoption
as a robust biomarker in clinical practice.
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566-06-015.
Quantitative MRI Assessment of Vertebral Marrow Fat Remodeling Across Aging in Women Using mDIXON-Quant
Impact: mDIXON-Quant enables
rapid 3D assessment of vertebral marrow fat remodeling across aging, providing
a radiation-free biomarker for early metabolic bone quality evaluation in women
beyond conventional BMD.
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