Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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569-04-001.
Accelerated Bloch-Siegert B1+ mapping using concentric ring sampling for 31P MRS in the muscle and liver at 7T
Impact: 3D-CRT 7T 31P B1+ mapping covers a 300x300x200mm
volume in the liver at 25mm resolution in 3D within 10 minutes. This is a key step towards 3D-resolved
saturation transfer measurements, and the quantification of phosphorus
metabolites in large organs.
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569-04-002.
Multi-shot 2D Selective Excitation for Extracranial Lipid Suppression in MR Spectroscopic Imaging of the Brain
Impact: Achieving full brain coverage MRSI without lipid contamination is valuable for the adaptation of MRSI in clinical procedures. Our method of two-dimensional selective excitation allows for greatly reduced lipid contamination in MRSI without the need for post processing lipid removal.
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569-04-003.
Accelerated J-Resolved Metabolite-Cycled Spectroscopic Imaging Using Rosette k-Space Trajectory (ROS-JRESI-MC): A Pilot Study
Impact: The sequence enabled full 4D MC-JRESI acquisition in under 10 minutes,
nearly twice as fast as conventional methods, with comparable spectral
quality. In vivo results showed multi-voxel metabolite quantification in
a 61-year-old volunteer.
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569-04-004.
First implementation of preclinical ¹H-FID-MRSI with Concentric Ring Trajectory for rodent brain metabolic mapping at 9.4T
Impact: CRT-FID-MRSI was successfully implemented on a preclinical scanner and tested in vivo, yielding similar metabolic maps as PE-FID-MRSI. The spectral-spatial encoding scheme will improve the acquisition efficiency and facilitate the acquisition of high-resolution 2D/3D-MRSI in the rodent brain.
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569-04-005.
Optimized B0 and B1-Insensitive Water Suppression for Rapid Whole-Slice Rosette MRSI Acquisition in the Brain
Impact: The water signal must be effectively
suppressed for accurate MRSI metabolite quantification. Our proposed 5-pulse
water suppression scheme is robust to brain-wide B0 and B1
inhomogeneities while permitting short TRs for rapid MRSI acquisition.
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569-04-006.
Tissue-Specific Neurochemical Profiling of White and Gray Matter in the Human Brain at 5T Using Short-TE STEAM MRS
Impact: This study demonstrates that $5~T$ STEAM $^1H$-MRS enables robust, tissue-specific metabolite quantification with enhanced spectral quality and reproducibility, establishing a practical framework for high-field neurochemical mapping and future clinical translation.
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569-04-007.
Enhancing Reliability in Deep Learning Metabolite Quantification: Evaluating Uncertainty Estimation Approaches
Impact: This work advances MRSI quantification by systematically comparing deep learning-based uncertainty estimation methods, highlighting their performance and calibration limits, and paving the way for more trustworthy and clinically applicable metabolite quantification by artificial intelligence.
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569-04-008.
ABSOLUTE QUANTIFICATION OF CARDIAC ENERGETICS IN HEART FAILURE PATIENTS USING 31P MRS AT 3T
Impact: Integration of this method into clinical workflow could improve the accuracy
of cardiac metabolic measurements and support the development of targeted
therapies for improved patient outcomes.
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569-04-009.
Streamlined whole-brain spectroscopic imaging using SLOW-EPSI at 7T: a spectroscopist-free solution for the clinic
Impact: Enables fast, spectroscopist-free whole-brain MRSI at 7T—Cho/Cr/Glx maps at 4.3-mm in 5:30. Reconstruction and post-processing can, in principle, run online on the scanner like a product sequence, requiring no advanced algorithms.
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569-04-010.
Deep Learning–Based Reconstruction: Model Comparison for Variable-Density GRAPPA 1H MRSI
Impact: This study demonstrates that deep learning–based reconstruction methods can substantially accelerate proton MRSI acquisitions. By accurately recovering missing k-space data, the proposed AI models enable up to 4-fold faster scans—reducing a typical 10-minute acquisition to 3 minutes (R = 4).
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569-04-011.
Measuring brain metabolite diffusion parameters using DW-MRS: A preliminary study on 5T
Impact: The proposed DW-MRS study shows the feasibility of measuring
brain metabolite diffusion parameters on a whole-body 5T system. The success of
the proposed method demonstrates the potential of investigating brain microstructure
changes under different pathophysiological conditions on clinical high-field
systems.
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569-04-012.
Improved Single-Voxel Short-Echo 1H MR Spectroscopy (SVS) of Human Brain on a Clinical 5T MR Platform
Impact: High quality of short-echo spectroscopy on a clinical 5T platform is crucial for routine clinical usages. The applied outer-volume-suppression together with the adjustable WET allow acquiring spectra of both human gray-matter and white-matter rich regions with substantial improvements.
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569-04-013.
Comparison of pulse sequences for downfield MR spectroscopic imaging in the human brain at 7T
Impact: This study suggests that optimized excitation and refocusing schemes can enhance the robustness
of downfield MR spectroscopic imaging (DF-MRSI). These findings may help guide future sequence design for improved
detection of amide and other downfield resonances in the human brain.
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569-04-014.
A comparison of methods for high-resolution 31P B1 Mapping
Impact: This work demonstrates that the phase sensitive B1 mapping
is suitable for high-resolution B1 mapping of 31P on a pre-clinical
high-field system. This is important for accurate quantification of 31P-metabolite
signals.
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