Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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361-06-001.
Myelin Loss in Olfactory–Limbic Circuits Predicts Olfactory and Memory Impairment in MCI
Impact: This work demonstrates that myelin mapping via
MVF enables early detection of Alzheimer's-related network degeneration,
allowing improved risk stratification in older adults with olfactory or
cognitive symptoms.
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361-06-002.
Cerebral Microbleed Detection Using Clinically Feasible Multi-shot Multi-echo Echo Planar Imaging at 3T
Impact: Multi-shot multi-echo 3D echo planar imaging may enhance the reliability
and accuracy for detecting cerebral microbleeds after traumatic brain injury,
potentially improving longitudinal assessment of small vascular injury which is
associated with cognitive decline.
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361-06-003.
T1 Mapping at 7T Using Multi-Contrast MPRAGE with field-mapping correction of Inversion Efficiency and Flip Angle
Impact: This work enables a stable and flexible voxel-wise $T_1$ mapping at 7T by incorporating multiple inversion times, flip angle, and inversion efficiency, supporting flexible acquisition and direct model fitting informed by $B_1^+$/$B_0$ field maps.
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361-06-004.
Accelerated MR Parameter Mapping using A Generative Network Representation
Impact: Quantitative MRI provides objective measures for tissue characterization, disease diagnosis and treatment monitoring, but has been limited in the clinics due to long scan times. This work achieved high-quality qMRI from highly accelerated acquisitions using an efficient generative network representation.
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361-06-005.
Slice-to-slice initialization for accelerated Deep Image Prior reconstruction of 3D MRF maps
Impact: We
propose to accelerate DIP-MRF reconstruction of 3D datasets based on early
stopping and transfer learning. Our approach proves accurate while preserving DIP-MRF scan specificity. This acceleration strategy makes DIP-MRF more practical,
potentially enabling its broader adoption.
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361-06-006.
SAR-optimised and accelerated T2 mapping at 7T using the MESE sequence and an EPG-model-based reconstruction
Impact: This work demonstrates accelerated and SAR-optimised T2
mapping at 7T using model-based reconstruction, enabling whole-brain
quantitative mapping in clinically feasible scan times.
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361-06-007.
In vivo repeatability of fast whole-brain relaxometry with MR-STAT
Impact: Our work demonstrates
that MR-STAT provides highly repeatable $T_1$/$T_2$-quantification,
a critical requirement for clinical implementation. This reliability ensures
consistent biomarker measurement across sessions, enabling accurate monitoring
of disease progression, treatment response, and longitudinal changes in
individual patients.
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361-06-008.
Microstructural Assessment of Oral Squamous Cell Carcinoma Using Time-Dependent Diffusion MRI
Impact: Time-dependent diffusion contrast shows greater specificity for tumor cells and may help disentangle contributions from different cell types, providing insights into oral squamous cell carcinoma microstructure that are not captured by the conventional apparent diffusion coefficient.
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361-06-009.
B1+ Mapping Using Accelerated Actual Flip-Angle Imaging for Accurate T1 Mapping by MP2RAGE in the Brain and Cervical Cord
Impact: In 3D actual flip-angle imaging, reduced
through-plane resolution and compressed SENSE acceleration enable a ~78%
reduction in acquisition time (7:43 vs. 1:43 min). This facilitates fast transmit bias field (B1+) mapping, which is crucial for accurate T1 mapping by MP2RAGE.
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361-06-010.
Motion-resolved 3D carotid vessel wall T1 mapping: reproducibility from a 64-element head-neck to a 2-element carotid coil
Impact: Motion-resolved free-running
inversion-recovery T1
mapping with two interleaved flip angles and a top-to-bottom phyllotaxis
trajectory allows for the generation of precise respiratory-resolved 3D T1 maps and gray-blood
images using a clinical head-neck coil and a custom carotid coil.
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361-06-011.
Myelin imaging of the optic nerve
Impact: Quantitative myelin imaging of the optic nerve using MP2RAGE-derived myelin volume fraction maps enables in-vivo assessment of white-matter microstructure integrity in a small, clinically relevant tract, potentially improving monitoring of demyelinating disorders such as multiple sclerosis.
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361-06-012.
High-Resolution Fast Quantitative Magnetization Transfer Imaging at 7T in the Human Brain
Impact: Quantitative Magnetization Transfer at 7T from highly-accelerated MT-prepared SPGR
sequences is implemented for the joint estimation of MPF and apparent T1
maps, yielding 0.7-mm isotropic maps of the whole human brain in 16 minutes.
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361-06-013.
Study of MT-induced T1 differences between normal controls and mild traumatic brain injury patients
Impact: The incidence of mTBI is almost double that of multiple sclerosis, Parkinson’s disease, Alzheimer’s disease and stroke combined. There is no routine imaging biomarker for mTBI however recent studies indicate there is a measurable difference in T1 under MT.
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361-06-014.
Partial Diffusion for Accelerated 3D Silent Multi-Parametric Zero Echo Time Acquisition (MuPa-ZTE)
Impact: The
proposed partial diffusion-based enhancement enables high-quality $1.1mm^3$ isotropic multi-parametric qMRI with 1.5 minutes scanning time, facilitating its integration
into clinical workflows.
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361-06-015.
Design of custom multi-material hydrogel printer for multi-contrast MRI phantoms
Impact: This work introduces a multi-material MSLA printing platform for fabricating boundaryless, anatomically accurate MRI phantoms using UV-curable hydrogels with tunable contrast. The approach enables automated, reproducible production of multi-contrast phantoms, advancing accessibility and standardization in quantitative MRI calibration and validation.
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