Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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669-04-001.
Intravenous glucose stimulated pancreas BOLD MRI: preliminary findings in normoglycemic individuals with cystic fibrosis
Impact: Preliminary
findings show differences in pancreas BOLD MRI response after
intravenous glucose stimulation between individuals with and without cystic
fibrosis, consistent with differences in beta-cell functional response. These findings show translational potential for assessing
pancreas metabolic abnormalities that precede diabetes.
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669-04-002.
Multiparametric MRI to assess the Effects of Oxygenated Hypothermic Machine Perfusion on Ex-Vivo Pancreases
Impact: This work demonstrates the feasibility of ex-vivo
quantitative MRI to study the pancreas and assess the effects of preservation
techniques. In future, a proven method for non-invasive assessment of the
pancreas prior to transplant could improve transplant rates.
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669-04-003.
Clinical evaluation of deep learning accelerated 3D magnetic resonance cholangiopancreatography at 1.5T and 3T
Impact: Deep learning accelerated, Deep Learning Speed (DLS),
MRCP (breath-hold 11-17s) has better image quality consistency with shorter
scan time compared to standard MRCP performed either as resolution breath‐hold
(BH) acquisition or higher resolution triggered navigator breathing (NAV)
acquisition.
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669-04-004.
MR Elastography in the pancreas and pancreatic ductal adenocarcinoma
Impact: This work demonstrates that MRE-derived stiffness
quantification discriminates PDAC from other pancreatic lesions and associates
with treatment response. These promising results underscore the need for further MRE validation with
quantifying stromal deposition to establish stiffness as a predictor for
response.
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669-04-005.
Deep learning-based pancreatic age estimation from MRI predicts incident diabetes beyond known risk factors
Impact: Organ-specific biological age estimation of the pancreas from MRI-derived segmentation masks (MRI-PancAge) predicts future type 2 diabetes beyond chronological age and known risk factors. Individuals at high MRI-PancAge could benefit from personalized prevention strategies, lifestyle interventions, and treatment planning.
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669-04-006.
Assessing Fibrotic Multimorbidity using Multiorgan MRI data in the UK Biobank
Impact: Fibrotic diseases cause multiorgan changes which are measurable
using quantitative MRI. Population level MRI changes in the UK Biobank allowed
MRI patterns associated with fibrotic disease to be identified and an MRI-based Fibrotic
MultiMorbidity Score generated to assess mortality risk.
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669-04-007.
Small-bowel motility is lower in humans with obesity vs. healthy weight and this is altered by weight loss – an MRI study
Impact: This
study identifies small-bowel motility differences in obesity vs. healthy
bodyweight and alterations in obese individuals after weight loss, offering a
non-invasive method for gut-brain-axis research to understand the mechanisms
underlying motility changes and guide researchers to new therapies.
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669-04-008.
Multiparametric MRI Assessment of Crohn’s Disease Activity: Comparative Diagnostic Performance of ADC, K, and RCE
Impact: Ultrafast
dynamic enhancement slope (K) provides superior diagnostic accuracy for Crohn’s
disease activity compared with ADC and RCE. Integrating multiparametric MRI
enhances noninvasive disease monitoring, potentially reducing reliance on
invasive endoscopy in clinical management.
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669-04-009.
Dual-modality imaging strategy of preoperative MRI and intraoperative NIRF targeting perineural invasion of pancreatic cancer
Impact: This novel GAP-43-targeting probe enables precise preoperative MRI and intraoperative navigation of perineural invasion, aiding surgeons in achieving complete tumor resection and improving patient survival in pancreatic cancer.
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669-04-010.
Pancreatic T1, T2, T2* and PDFF in Healthy Indian Adult Population at 3.0T
Impact: We establish the subregion-wise (head, body, tail)
normal ranges of the pancreatic MR relaxation properties and proton density fat
fraction in Indian healthy adult population. These nomograms can serve as
reference values for planning future studies evaluating pancreatic diseases.
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669-04-011.
Bowel Wall Relaxation in the Human Gut: Preliminary Findings at 3.0T
Impact: We present $T_1$ relaxation maps of the
bowel walls at 3T and as-of-yet unreported mean $T_1$ values in healthy male volunteers. This preliminary data may
inform pulse sequence and protocol design for abdominal imaging for digestive
diseases.
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669-04-012.
User-independent AI-based MRI analysis of hepatobiliary function in patients with primary sclerosing cholangitis
Impact: Our AI-based workflow transforms hepatobiliary
phase-based biomarkers into practical clinical tools that enable regionally
differentiated liver function assessment in a rapid and objective manner -
potentially facilitating personalized monitoring in chronic liver diseases such
as primary sclerosing cholangitis.
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669-04-013.
Thin-Slice Oblique Coronal Zoomed DWI on Ultra-High Gradient System: Improved Evaluation of Extrahepatic Cholangiocarcinoma
Impact: Thin-slice
Oblique Coronal Zoomed DWI on an ultra-high gradient system demonstrates improved image quality, enhanced lesion delineation and more
accurate tumor sizing for eCCA evaluation, showing
strong potential for precise preoperative assessment and surgical guidance.
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669-04-014.
Interrogating preventative treatment efficacy in premalignant pancreatic cysts by hyperpolarized magnetic resonance
Impact: The ability to detect precancerous pancreatic lesions and prevent
pancreatic cancer would revolutionize patient care and pancreatic cancer
outcomes. HP-MR can detect these lesions and evaluate the efficacy of a KRAS
inhibitor to reverse the onset of pancreatic cancer.
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669-04-015.
The Value of focused MRI Protocols in Assessing Cystic Pancreatic Lesions
Impact: Adopting focused MRI (fMRI) protocols for cystic pancreatic lesion assessment can enhance patient care by offering diagnostic accuracy similar to comprehensive MRI while optimizing exam times, patient comfort and resources.
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