Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition - Analysis in Neurodegenerative Disease

Analysis in Neurodegenerative Disease

Traditional Poster

Analysis Methods

Monday, 11 May 2026

Traditional Posters | Exhibition Hall

13:50 - 14:45

Session Number: 370-04

No CME/CE Credit

Similar Sessions

The session covers analysis of MRI markers of neurodegenerative disease.

Skill Level: Basic,Intermediate,Advanced

		370-04-028. Atrophy in cortical thickness, cognitive deficits, and their transcriptomic signatures in patients with non-neuropsychiatric yuxuan Shang, Peng Li, Wen Wang Tangdu Hospital, Shaanxi, China Impact: In the organization of the reduced cortical thickness in non-NPSLE patients is likely driven by the effect of neurodegenerative processes.
		370-04-029. Iron accumulation in Caudate and its associations with age and sex across hemispheres in Parkinson’s disease Arpita Misra, Ana-Maria Oros-Peusquens, Kathrin Reetz, Imis Dogan, Jörg Schulz, Yi Wang, N. Jon Shah, Junghun Cho George Washington University, Washington, United States of America Impact: This study demonstrates feasibility of QQ, a novel technique for quantifying neural tissue iron. QQ’s non-blood susceptibility parameter ($\chi_n$) serves as reliable surrogate for iron accumulation, enhancing understanding of iron-related pathophysiology in Parkinson’s disease and other neurodegenerative disorders.
		370-04-030. Fast susceptibility imaging and mapping for Parkinson’s disease Jonghyo Youn, Chungseok Oh, Jongho Lee Seoul National University, Seoul, Korea, Republic of Impact: This study optimized a segmented-EPI sequence to generate SWI, SMWI, QSM, and χ-separation maps with image quality comparable to conventional GRE while reducing scan time (< 3 min), thereby improving clinical applicability in diagnosing neurodegenerative diseases such as Parkinson’s disease.
		370-04-031. 23NaMRI signal separation based on T2 relaxation in patients with Alzheimer’s Disease and matched healthy controls Sara Hejazi, Ying-Chia Lin, Alaleh Alivar, Kennedy Watson, Kamri Clarke, Justin Quimbo, Malika Kumbella, Simon Henin, Yulin Ge, Arjun Masurkar, Anli Liu, Fernando Boada, Yvonne Lui, Yongxian Qian Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, United States of America Impact: This work demonstrates the potential of separated sodium imaging to reveal both neuronal loss and preserved neuronal function in Alzheimer’s disease. By distinguishing sodium components, this approach may serve as a sensitive biomarker for early neurodegenerative alterations.
		370-04-032. Multi-contrast cerebrovascular reactivity and noise mapping in Alzheimer’s disease Maria Guidi, Giovanni Giulietti, Taljinder Singh, Matteo Mancini, Mauro DiNuzzo, Sabrina Bonarota, Giulia Caruso, Carlotta Di Domenico, Fabrizio Esposito, Laura Serra, Carlo Caltagirone, Giovanni Augusto Carlesimo, Federico Giove CREF - Enrico Fermi Research Center, Rome, Italy Impact: This work advances the understanding of cerebrovascular reactivity’s impact on functional MRI signals by integrating multi-contrast CVR measures with TE-independent noise analysis. It improves interpretation of vascular and non-neural contributions in fMRI, enhancing biomarker specificity for aging and neurodegenerative diseases.
		370-04-033. Pathway‐Anchored QSM Radiomics of an Iron‐Enriched Motor Circuit: Early, Sensitive Detection and Clinical Translation in ALS Tao Lu, Shan Wu, Xinyi Yu, Ningkui Hong, Jia Zhe, Weixia Mao, bao qin guo, Yi Zhu, Qiuli Zhang, Ming Zhang The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China Impact: Pathway-level QSM radiomics detects ALS-related iron dysregulation, enabling risk flagging, imaging endpoints for iron/redox trials, and studies of iron–oxidative stress. It shifts biomarkers from averages to textures, motivating multicenter validation and multimodal integration to translate susceptibility mapping into decision support.
		370-04-034. GluCEST MRI reveals glutamate as a biomarker for neuroinflammation and neurodegeneration Ongira Chowdhury, Kasturee Chakraborty, Ritambhar Burman, Claire Vania, Puneet Bagga St. Jude Children's Research Hospital, Memphis, United States of America Impact: In the long term, high-resolution, noninvasive GluCEST imaging offers strong potential for monitoring various neuroinflammatory and neurodegenerative diseases, providing a robust tool for early diagnosis, treatment assessment, and designing targeted therapies to enhance clinical outcomes.
		370-04-035. Perfusion Measurements in Gliomas and Cognitive Decline Continuum in Alzheimer’s Disease Using BBB-ASL MRI Gülce Turhan, Beatriz Padrela, Ayse Irem Cetin, Amnah Mahroo, Simon Konstandin, Daniel Christopher Hoinkiss, Nora-Josefin Breutigam, Vera Keil, Ayca Ersen Danyeli, Koray Özduman, Atle Bjørnerud, Sandra Tecelão, Per Selnes, Oliver Geier, Klaus Eickel, Henk Mutsaerts, Tormod Fladby, Matthias Günther, Jan Petr, Alp Dinçer, Esin Ozturk Isik Bogazici University, Istanbul, Turkey Impact: Multi-TE BBB-ASL MRI provides a non-invasive approach to measure BBB disruptions in normal appearing white matter of gliomas and neurodegenerative diseases. Lower CBF in cognitive decline continuum in Alzheimer’s diseases and lower Tex in gliomas were observed.
		370-04-036. Quantitative Analysis of Substantia Nigra Margin Blurring for Early Parkinson’s Disease Diagnosis fei liu, guangbin wang, Xiuzheng Yue, Tao Gong Impact: This method demonstrates higher sensitivity than conventional ROI analysis and holds potential as an imaging biomarker for early PD diagnosis.