Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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365-03-001.
Perfusion fraction mapping in the prostate with state-of-the-art intravoxel incoherent motion (IVIM) MRI
Impact: Our state-of-the-art velocity-compensated IVIM exposes that conventional prostate IVIM yields biases in diffusivity and perfusion fraction. This warrants the consideration of velocity-compensation for reliable IVIM experiments, pending further validation.
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365-03-002.
A Deep learning-based Spectral Analysis of Multi-Exponential Intravoxel Incoherent Motion (D-SAME-IVIM) MRI of the Kidney
Impact: A
robust and fast method for spectral diffusion analysis capable of detecting
pathophysiological changes in the kidney from multi-b-value DWI data.
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365-03-003.
Deep learning reconstruction for accelerated and quality-preserving liver IVIM protocols
Impact: The use of deep learning-based image reconstruction on IVIM-DWI liver
imaging allows accelerating the acquisition while simultaneously preserving
image quality and improving the reliability of IVIM parameter estimation, potentially
offering a faster framework for non-contrast liver imaging.
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365-03-004.
Image Quality in Breast DWI Using DL readout-segmented EPI: A Comparison with Standard readout-segmented EPI at 3T
Impact: DL rs-EPI improves diffusion image quality and
lesion visibility without affecting maintaining similar ADC values. Its shorter
acquisition time and comparable performance supports clinical implementation
for faster, more robust breast MRI in the clinical practice.
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365-03-005.
Optimization of Respiratory Synchronization for Abdominal Intravoxel Incoherent Motion MRI in the Renal Medulla
Impact: This
study provides practical guidance for optimizing abdominal intravoxel
incoherent motion acquisition. Trigger and track synchronization and a 3-beat repetition time can improve the accuracy and reproducibility of
perfusion and diffusion parameters in the renal medulla, enhancing diagnostic
reliability.
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365-03-006.
Hybrid Diffusion of Cervical-Thoracic Pediatric Spinal Cord: Normative Analysis of NODDI, DKI, and DTI Metrics
Impact: First pediatric, tissue-specific diffusion reference curves (DTI, DKI, NODDI) across C1-T12 enable z-score outlier detection and age-adjusted interpretation. They provide effect-size anchors for normal development and a baseline for clinical and research uses, including pediatric SCI, transverse myelitis, and myelopathy.
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365-03-007.
Evaluation of generalist, on-the-scanner, deep learning recon for M2SE cardiac DTI
Impact: Generalist, on-the-scanner, deep learning recon appears to achieve
comparable to non-deep learning cardiac diffusion tensor imaging (DTI) results with a reduced scan
time. This may improve feasibility of cardiac DTI on clinical scanners where
time is short.
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365-03-008.
Two-Step Fitting Enables Improved Precision of Simultaneous IVIM and Compartmental R2 Quantification
Impact: Two- versus one-step fitting improved the noise performance
and test-retest repeatability of the perfusion signal fraction and R2
of blood when performing simultaneous IVIM and compartmental R2
quantification. The improved repeatability may enhance clinical diagnostic
value and enable treatment monitoring.
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365-03-009.
Comparison of Conventional and Deep Neural Network IVIM Fitting Strategies for Soft-Tissue Tumor Characterization
Impact: This study demonstrates that DNN–based IVIM fitting achieves reproducible diffusion parameters and comparable diagnostic performance to IVIM segmented nonlinear least squares fitting, while reducing parameter variability. These findings may promote clinical translation of IVIM for reliable soft-tissue tumor characterization.
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365-03-010.
Decoding Tumor and Muscle Microstructure in HNC via Simplified IVIM MRI
Impact: This study demonstrates the potential of simplified IVIM
MRI to evaluate both macrostructural and microstructural changes in the
masseter muscle of HNC patients, providing valuable insights into altered tumor
microenvironments and cancer-related muscle inflammation for improved prognosis
prediction.
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365-03-011.
Enhanced Intravoxel Incoherent Motion three-compartmental modeling using fusion neural network
Impact: We propose a fusion network for Intravoxel Incoherent Motion
(IVIM) modeling that leverages T1-weighted and FLAIR anatomical priors to
improve estimation of tissue diffusion and perfusion characteristics.
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365-03-012.
Highly Efficient Cardiac Diffusion Tensor Imaging Using Interleaved Simultaneous Multi-Slice Motion-Compensated Spin-Echo
Impact: The proposed interleaved simultaneous multi-slice flip-back motion-compensated spin-echo significantly improves the efficiency of cDTI acquisitions, enabling whole-heart coverage within 20-30 minutes while maintaining image quality, paving the way for whole-heart cDTI as an add-on to clinical exams.
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365-03-013.
AI-THiNR: A Modular AI Toolbox for Quantitative Multicontrast MRI of Head and Neck Tumors
Impact: AI-THiNR is a comprehensive AI toolbox for
multicontrast MRI analysis. It integrates convolutional neural network (CNN)-based
deep feature extraction and physics-based diffusion modeling, enabling tumor
characterization, improved diagnostic precision, and scalable clinical
translation in head-and-neck oncology.
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365-03-014.
Gender and Age Effects on Lumbar Paraspinal Muscles: A Multimodal MRI Study Correlating DTI, PDFF and Muscle Strength
Impact: This study provides novel insights into paraspinal muscle degeneration,
demonstrating multimodal MRI's capability to detect microstructural changes
predictive of functional decline, potentially enabling early intervention for
age-related spinal disorders.
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365-03-015.
Definition of a liver function index using intra-voxel incoherent motion modelling for function-guided liver cancer radiation
Impact: This study introduces a liver
functional index to generate voxel-wise liver function maps, enabling
functional-avoidance radiation therapy for patients with HCC and impaired liver
function.
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© 2026 International Society for Magnetic Resonance in Medicine