Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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302-02-001.
Functional lung MRI during tachypnea detects changes in regional ventilation after dual bronchodilator treatment in COPD
Impact: Metronome-paced tachypnea is a feasible
alternative to exercise testing and demonstrates greater sensitivity to single-dose
dual bronchodilator effects in COPD patients when assessed using single-slice
functional lung MRI.
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| 08:31 |
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302-02-002.
Phase-resolved functional lung (PREFUL) versus arterial spin labeling (ASL) MRI for noninvasive measurement of lung perfusion
Impact: This study compares two noninvasive techniques for quantitative assessment of lung
perfusion. The PCASL technique yields higher perfusion values than those measured with PREFUL. Further efforts are needed to better understand the reasons for the differences between the two methods.
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| 08:42 |
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302-02-003.
Categorical 1H VOLVE Lung MRI Quantifies Ventilation Magnitude and Delay in Cystic Fibrosis and CFTR Modulator Response
Impact: VOLVE
analysis provides quantitative assessment of regional ventilation amplitude and
delay in people with CF. Categorical metrics highlight clinically relevant differences
and therapy-related changes not reflected by spirometry, supporting the use of MRI
in longitudinal evaluation of regional lung function.
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| 08:53 |
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302-02-004.
Pulmonary ventilation mapping using a non-commercial very-low field MRI system
Impact: We
demonstrate the feasibility of 3D-lung ventilation mapping across the pulmonary
respiratory cycle using an approach tailored to hardware constraints typical of emerging very-low field MRI systems. Once validated, such mapping methods could support future diagnosis in communities and children.
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| 09:04 |
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302-02-005.
An ALP-MRI Score for Assessing Combined Structural and Functional Lung Performance in Neonatal Bronchopulmonary Dysplasia
Impact: The ALP-MRI score
combines structural and functional lung metrics into a single score which
differentiates between BPD Grades 1 and 2/3. The score identifies abnormalities
in each of the three main lung compartments of airways, lung parenchyma and
pulmonary vasculature.
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| 09:15 |
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302-02-006.
RadiolGAN: A Multicenter Study of Synthetic CT from 3D UTE MRI to Enhance Pulmonary Radiologic Sign Visualization
Impact: RadiolGAN enables high-fidelity UTE-to-CT image translation, enhancing the depiction of radiologic features and structural details across diverse lung conditions. This approach highlights the potential role of GAN-based synthesis in supporting future clinical applications of lung MRI.
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| 09:26 |
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302-02-007.
A Novel Independent Component Analysis Method for Non-Contrast-Enhanced Pulmonary Ventilation and Perfusion MRI
Impact: We introduce a new robust free-breathing technique for non-contrast-enhanced functional lung imaging based on independent component analysis, evaluated on 0.35 T MR-Linac. It improves key limitations of standard methods, like sensitivity to irregular breathing and motion artifacts.
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| 09:37 |
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302-02-008.
Phase-resolved functional lung and 19F MRI detect early treatment response to mepolizumab in patients with severe asthma
Impact: PREFUL and 19F MRI enable early, non-invasive assessment of anti-interleukin-5 biologic treatment response in severe asthma. These functional imaging techniques outperform global spirometry, offering sensitive regional markers for monitoring biologic therapy effects and guiding personalized asthma management.
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| 09:48 |
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302-02-009.
Real-Time Tracking of Tumor-Associated Macrophages In Vivo Using Hyperpolarized 129Xe MRI
Impact: This
study establishes a novel, non-invasive and radiation-free molecular imaging strategy for early
lung cancer detection in living
subjects.
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| 09:59 |
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302-02-010.
Simplifying Hyperpolarized Xenon Pulmonary Gas-Exchange MRI
Impact: Initial calibrations to determine TE90 for dissolved-phase Dixon decomposition require additional hyperpolarized 129Xe doses that drive up cost and complexity. We developed a method to correct images acquired at arbitrary TE, thus obviating the need for initial calibration scans.
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© 2026 International Society for Magnetic Resonance in Medicine