Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Lung and Thoracic Oncological MRI

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Lung and Thoracic Oncological MRI
Digital Poster
Body
Wednesday, 13 May 2026
Digital Posters Row C
08:20 - 09:15
Session Number: 562-01
No CME/CE Credit
This digital session includes presentations that utilize state-of-the-art lung and thoracic oncologic MR imaging.
Skill Level: Basic

  Figure 562-01-001.  129Xe MRI-based microstructure metrics offer superior sensitivity for COPD identification
Ziwei Zhang, Li Fan, Yuanyuan Cui
The Second Affiliated Hospital of Naval Medical University, SHANGHAI, China
Impact: For the objective identification of COPD, 129Xe MRI-based microstructure metrics offer superior sensitivity compared to ventilation-based metrics.
  Figure 562-01-002.  Improving the Repeatability of Corrected 129Xe Red Blood Cell Oscillations Using Patient-Specific Considerations
Zhuchenxin Li, Anna Costelle, David Mummy, Hong Qin, Seth Lee, Suphachart Leewiwatwong, Bastiaan Driehuys
Duke University, Durham, United States of America
Impact: 129Xe RBC oscillations corrected for RBC transfer defects using published methods can detect elevated pulmonary vascular resistance. Accounting for patient-specific factors improves repeatability, thereby advancing the potential of this technique to aid in diagnosis and management of pulmonary hypertension.
  Figure 562-01-003.  Quantification of Membrane-Capillary Gas Exchange in Pulmonary Fibrosis Using Hyperpolarized 129Xe MR
Ming Zhang, Haidong Li, Hongchuang Li, Xiuchao Zhao, xiaoling liu, Yu Zheng, Yeqing Han, Chuan Qin, Xin Zhou
State Key Laboratory of Magnetic Resonance Spectroscopy and Imaging, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China
Impact: This study introduces a quantitative ¹²⁹Xe MR technique for assessing alveolar-capillary gas exchange kinetics, enabling sensitive, noninvasive evaluation of microvascular remodeling in pulmonary fibrosis and offering translational potential for clinical gas exchange evaluation.
  Figure 562-01-004.  Comparison of 129-Xenon ventilation MRI protocols at 1.5T and 3T
Yves Brown, Guilhem Collier, Alberto Biancardi, Neil Stewart, Laurie Smith, Jim Wild
The University of Sheffield, Sheffield, United Kingdom
Impact: Minimal difference was found quantitatively and qualitatively between 129-Xenon ventilation MRI acquired at 1.5T and 3T using optimised sequences. Our results are promising for wider clinical adoption of this technique across different MR centres.
  Figure 562-01-005.  Multivariate metal-organic frameworks for 129Xe magnetic resonance imaging of lung cancers
zhongyu xiao, Qingbin Zeng, Xiuchao Zhao, Qianni Guo, Xin Zhou
Innovation Academy for Precision Measurement Science and Technology,CAS, Wuhan, China
Impact: The design strategy of ZIF-8A@BSA is expected to improve the signal-to-noise ratio and diagnostic information content in lung disease imaging, addressing the sensitivity limitations of conventional contrast agents.
  Figure 562-01-006.  REGIONAL VENTILATION MAPPED BY 3D PHASE-RESOLVED FUNCTIONAL LUNG MRI IMPROVES AFTER BRONCHODILATOR TREATMENT IN SEVERE ASTHMA
Filip Klimeš, Chuan Foo, Andreas Voskrebenzev, Marius Klein, Richard McIntyre, Frank Wacker, Jens Vogel-Claussen, Francis Thien
Hannover Medical School, Hannover, Germany
Impact: 3D PREFUL MRI derived ventilation parameters show significantly reduced ventilation defects in severe asthma patients after bronchodilator. This positions 3D PREFUL MRI as a promising candidate for non-invasive monitoring of regional ventilation changes in future clinical studies.
  Figure 562-01-007.  Non-Contrast-Enhanced 4D Ventilation Mapping from Highly Accelerated Time-Resolved 4D MRI of the lungs
Filip Klimeš, Andreas Voskrebenzev, Jingjia Chen, Frank Wacker, Hersh Chandarana, Jens Vogel-Claussen, Li Feng
Hannover Medical School, Hannover, Germany
Impact: Accelerated free-breathing MRI demonstrated feasibility and produced plausible results in healthy volunteers. Ventilation maps remained stable even when scan times were reduced to 3.3 minutes. These findings support the potential for clinical relevance of 3D/4D methods, particularly in pediatric populations.
  Figure 562-01-008.  Continuous Slice Cycling for High-Signal Pulmonary Ventilation Imaging at 3T
Andrea Leuthard, Grzegorz Bauman, Oliver Bieri
University of Basel, Basel, Switzerland
Impact: CSC allows pulmonary ventilation imaging with outstanding SNR as compared to standard time-resolved single slice methods. The clinical prospects of a high-SNR, but ventilation-only method need to be further evaluated. It may be particularly valuable for imaging of destructive pathologies.
  Figure 562-01-009.  Zoom DWI Versus Conventional DWI: Efficacy of Image Quality and ADC Measurements in Patients with Mediastinal Lesions
Yoshiyuki Ozawa, Takahiro Ueda, Masahiko Nomura, Natsuka Yazawa, Kaori Yamamoto, Yuichiro Sano, Masato Ikedo, Takeshi Yoshikawa, Daisuke Takenaka, Yoshiharu Ohno
Fujita Health University, Toyoake, Japan
Impact: Zoom DWI can improve image distortion and has influence to image quality and tumor ADC measurement as compared with conventional DWI.
  Figure 562-01-010.  Multi-temporal MRI-derived Habitat Biomarkers for Assessing Response to Neoadjuvant Immunochemotherapy in NSCLC
Qiliang Wang, Jingyi Yang, Fangyuan Qu, chenjiao ran, Xiaoting Cai, Yicai Zhang, Chen Zhang, Lizhi Xie, Zhuo Ning, bole Gao, Ying Liu
Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer/Tianjin’s Clinical Research Center for Cancer/Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China
Impact: Multi-temporal MRI habitat analysis noninvasively decodes tumor heterogeneity dynamics during neoadjuvant immunochemotherapy in NSCLC, enabling early differentiation of responders from non-responders. This approach provides a radiation-free biomarker framework for individualized response prediction and adaptive treatment guidance.
  Figure 562-01-011.  Quantifying Alveolar Microstructure and Functional Alterations in CTD-ILD Patients Using Hyperpolarized 129Xe MRI
Yuxin Cheng, Yu Guan, LiDong Wang, Yi Xiao
The Second Affiliated Hospital of Naval Medical University, Shanghai, China
Impact: Using hyperpolarized Xenon MRI, this study furthers the understanding of the underlying pathological mechanisms in CTD-ILD with low diffusion capacity, providing evidence that loss of pulmonary capillaries is accompanied by pathological enlargement of alveolar structures.
  Figure 562-01-012.  Improving accuracy for the MR-based right-ventricular blood oxygen saturation measurements using T1, T2, and flow information
Alessio Perazzolo, Tzu Cheng Chao, Davide Curione, Micol Rebonato, Mara Pilari, Gianfranco Butera, Luigi Natale, Tim Leiner, Aurelio Secinaro
Mayo Clinic, Rochester, United States of America
Impact: Improved MR-based oxygenation modelling incorporating flow information enables noninvasive quantification of blood oxygen saturation using existing sequences from conventional CMR protocols, reducing reliance on catheterization and enhancing cardiopulmonary assessment, particularly in pediatric patients and across diverse clinical settings.

  Figure 562-01-013.  Comprehensive CMR Evaluation of Interventricular Septal Remodeling in Pulmonary Hypertension from Left Heart Disease
Ziqi Xiong, Fang Wang, Jingyun Shi
Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China
Impact: The systolic septum swing index, derived from CMR, reflects interventricular septal remodeling and ventricular interdependence alterations, independently distinguishing PH-LHD from pre-capillary PH. This quantitative biomarker may enhance early diagnosis and phenotypic differentiation.
  Figure 562-01-014.  “Two-for-one”: 3D cardiac and pulmonary MR imaging from a single acquisition using bSTAR
Pierre Daudé, Jordan Taylor, Joseph Plummer, Rajiv Ramasawmy, Anastasia Tsakirellis, Wiphada Bandettini, Marcus Chen, Adrienne Campbell-Washburn, Ahsan Javed
National Institutes of Health, Bethesda, United States of America
Impact: The ability to assess both cardiac and lung morphology and function in a single scan with parallel image reconstructions will facilitate the evaluation of the cardio-pulmonary interplay.
  Figure 562-01-015.  Fully Automated and Rapid 2D Shimming of the Lung in Free-Breathing
Pavlos Panos, Grzegorz Bauman, Oliver Bieri
University of Basel, Basel, Switzerland
Impact: The proposed fully automated, inline shimming method significantly reduced lung off-resonances. This leads to improved bSSFP image quality and reliability at 3T (or below) such as for functional lung MRI.

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