Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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562-01-001.
129Xe MRI-based microstructure metrics offer superior sensitivity for COPD identification
Impact: For the objective identification of COPD, 129Xe MRI-based microstructure metrics offer superior sensitivity compared to ventilation-based metrics.
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562-01-002.
Improving the Repeatability of Corrected 129Xe Red Blood Cell Oscillations Using Patient-Specific Considerations
Impact: 129Xe RBC oscillations corrected for RBC transfer defects using published methods can detect elevated pulmonary vascular resistance. Accounting for patient-specific factors improves repeatability, thereby advancing the potential of this technique to aid in diagnosis and management of pulmonary hypertension.
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562-01-003.
Quantification of Membrane-Capillary Gas Exchange in Pulmonary Fibrosis Using Hyperpolarized 129Xe MR
Impact: This
study introduces a quantitative ¹²⁹Xe MR technique for assessing
alveolar-capillary gas exchange kinetics, enabling sensitive, noninvasive
evaluation of microvascular remodeling in pulmonary fibrosis and offering
translational potential for clinical gas exchange evaluation.
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562-01-004.
Comparison of 129-Xenon ventilation MRI protocols at 1.5T and 3T
Impact: Minimal difference was found quantitatively and qualitatively between 129-Xenon ventilation MRI acquired at 1.5T and 3T using optimised sequences. Our results are promising for wider clinical adoption of this technique across different MR centres.
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562-01-005.
Multivariate metal-organic frameworks for 129Xe magnetic resonance imaging of lung cancers
Impact: The design strategy of ZIF-8A@BSA is expected to improve the signal-to-noise ratio and diagnostic information content in lung disease imaging, addressing the sensitivity limitations of conventional contrast agents.
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562-01-006.
REGIONAL VENTILATION MAPPED BY 3D PHASE-RESOLVED FUNCTIONAL LUNG MRI IMPROVES AFTER BRONCHODILATOR TREATMENT IN SEVERE ASTHMA
Impact: 3D PREFUL MRI derived ventilation parameters show significantly reduced ventilation defects in severe asthma patients after bronchodilator. This positions 3D PREFUL MRI as a promising candidate for non-invasive monitoring of regional ventilation changes in future clinical studies.
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562-01-007.
Non-Contrast-Enhanced 4D Ventilation Mapping from Highly Accelerated Time-Resolved 4D MRI of the lungs
Impact: Accelerated free-breathing MRI demonstrated feasibility and produced plausible results in healthy volunteers. Ventilation maps remained stable even when scan times were reduced to 3.3 minutes. These findings support the potential for clinical relevance of 3D/4D methods, particularly in pediatric populations.
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562-01-008.
Continuous Slice Cycling for High-Signal Pulmonary Ventilation Imaging at 3T
Impact: CSC allows pulmonary ventilation imaging with outstanding SNR as compared to standard time-resolved single slice methods. The clinical prospects of a high-SNR, but ventilation-only method need to be further evaluated. It may be particularly valuable for imaging of destructive pathologies.
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562-01-009.
Zoom DWI Versus Conventional DWI: Efficacy of Image Quality and ADC Measurements in Patients with Mediastinal Lesions
Impact: Zoom DWI can improve image distortion and has influence to image quality and tumor ADC measurement as compared with conventional DWI.
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562-01-010.
Multi-temporal MRI-derived Habitat Biomarkers for Assessing Response to Neoadjuvant Immunochemotherapy in NSCLC
Impact: Multi-temporal MRI habitat analysis noninvasively decodes tumor heterogeneity dynamics during neoadjuvant immunochemotherapy in NSCLC, enabling early differentiation of responders from non-responders. This approach provides a radiation-free biomarker framework for individualized response prediction and adaptive treatment guidance.
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562-01-011.
Quantifying Alveolar Microstructure and Functional Alterations in CTD-ILD Patients Using Hyperpolarized 129Xe MRI
Impact: Using hyperpolarized Xenon MRI, this study furthers the understanding of the underlying pathological mechanisms in CTD-ILD with low diffusion capacity, providing evidence that loss of pulmonary capillaries is accompanied by pathological enlargement of alveolar structures.
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562-01-012.
Improving accuracy for the MR-based right-ventricular blood oxygen saturation measurements using T1, T2, and flow information
Impact: Improved
MR-based oxygenation modelling incorporating flow information enables
noninvasive quantification of blood oxygen saturation using existing sequences
from conventional CMR protocols, reducing reliance on catheterization and
enhancing cardiopulmonary assessment, particularly in pediatric patients and
across diverse clinical settings.
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562-01-013.
Comprehensive CMR Evaluation of Interventricular Septal Remodeling in Pulmonary Hypertension from Left Heart Disease
Impact: The systolic septum swing index, derived from CMR,
reflects interventricular septal remodeling and ventricular interdependence
alterations, independently distinguishing PH-LHD from pre-capillary PH. This
quantitative biomarker may enhance early diagnosis and phenotypic
differentiation.
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562-01-014.
“Two-for-one”: 3D cardiac and pulmonary MR imaging from a single acquisition using bSTAR
Impact: The ability to assess both cardiac and
lung morphology and function in a single scan with parallel image
reconstructions will facilitate the evaluation
of the cardio-pulmonary interplay.
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562-01-015.
Fully Automated and Rapid 2D Shimming of the Lung in Free-Breathing
Impact: The proposed fully automated, inline shimming method significantly reduced
lung off-resonances. This leads to improved bSSFP image quality and reliability
at 3T (or below) such as for functional lung MRI.
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© 2026 International Society for Magnetic Resonance in Medicine