Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition

Heart Failure

Oral

Cardiovascular

Monday, 11 May 2026

Meeting Room 1.40

16:10 - 18:00

Moderators: Bram Coolen & Masaki Ishida

Session Number: 307-04

No CME/CE Credit

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This session focuses on prognostic and diagnostic markers of heart failure assessed by cardiac magnetic resonance imaging. It highlights the role of MRI-derived parameters in disease characterization, risk stratification, and outcome prediction.

16:10		307-04-001. Introduction Bram Coolen Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
16:21		307-04-002. Efficient High-Resolution Fat-Fraction Mapping for Myocardial Fat and Semaglutide Response in a Porcine HFpEF Model Xinheng Zhang, Mahmoud Elbatrik, Yuheng Huang, Archana Malagi, Chia Chi Yang, Li-Ting Huang, Miguel Huerta, David Lefer, Traci Goodchild, Hsin-Jung Yang Cedars-Sinai Medical Center, Los Angeles, United States of America Impact: We present an 8-minute, free-running whole-heart MRI sequence for high-resolution quantification of myocardial fat composition. This enables spatially resolved assessment of adipose remodeling and demonstrates as a powerful imaging biomarker for evaluating GLP-1 receptor agonist therapy in HFpEF patients.
16:32		307-04-003. Oral Contraceptive Use and HFpEF Probability in Women: CMR Insights from the UK Biobank Angela Rocca, Jonas Richiardi, Ruud van Heeswijk, Jaume Banus, Costa Georgantas, Philippe Meyer, Ambra Masi, Panagiotis Antiochos, Henri Lu, Juerg Schwitter, Roger Hullin Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland Impact: Our findings indicate that prior oral contraceptive use does not increase HFpEF probability after age adjustment, underscoring the need to explore other hormonal and metabolic mechanisms contributing to women’s higher HFpEF burden.
16:43		307-04-004. Diagnostic Value of CMR in HFpEF with Normal NT-proBNP: A Multiparametric Tissue Characterization Study Rui Zhang, Yi Zhu The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China Impact: This study provides clinicians a robust CMR-based diagnostic model for identifying HFpEF patients with normal NT-proBNP, addressing a critical diagnostic gap and enabling more accurate patient stratification for future research and targeted management.
16:54		307-04-005. Regional Cardiac Energy Metabolism Differences at 7T in Healthy, Diabetic, and Heart Failure Patients Jabrane Karkouri, William Watson, Jonathan Weir Mc-Call, Tracy Horn, Marion Hill, Dennis Klomp, Stephen Hoole, Chris Rodgers University of Cambridge, Cambridge, United Kingdom Impact: High-resolution ³¹P-MRSI with advanced coil technology enables in vivo mapping of cardiac energetics in heart failure and diabetes, providing a powerful tool to monitor treatment effects, stratify patients, and investigate mechanisms of SGLT2 inhibitors in metabolic cardiac disease.
17:05		307-04-006. Identifying Non-ischemic HFrEF Patients for Cardiac Resynchronization Therapy Beyond Current Guidelines: Insights from Cardia Di Zhou, Minjie Lu, Jing An Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Impact: This study enables refined patient selection for cardiac resynchronization therapy using CMR, helping clinicians personalize therapy to improve survival and avoid futile device implantations.
17:16		307-04-007. Stabilizing Histamine Release in Reperfused Myocardial Infarction Optimizes Inflammation and Mitigates Adverse Remodeling Joao Pedro Torres Neiva Rodrigues, Leon Riehakainen, Alan Kwan, Debiao Li, Ivan Cokic Cedars-Sinai Medical Center, Los Angeles, United States of America Impact: We provide initial evidence that mast cell stabilization via over-the-counter loratadine has the potential to be a novel therapeutic strategy for prevention of heart failure post-myocardial infarction.
17:27		307-04-008. Stratified Prognostic Value of Myocardial Fibrosis by LGE in CRT: Non-Linear Relationship and Threshold-Based Risk Prediction Shuang Li, Baiyan Zhuang, Zhao Wang, BingYan Shu, Chen Cui, jianxiu lian, Qingyuan Li, Wei Chen, Yue Ren, Koen Nieman, Lei Xu Beijing Anzhen Hospital, Capital Medical University, Beijing, China Impact: This CMR-based stratified model refines pre-CRT prognosis by identifying distinct risk drivers based on scar burden, enabling personalized patient management and potentially improving therapeutic outcomes through targeted monitoring and candidate selection.
17:38		307-04-009. The association between myocardial fibrosis and hemodynamics in ischemic and dilated cardiomyopathy: A preliminary study Qimin Fang, Jiahui Zhang, Jiankun Dai, Xin Zhang, Yipei Song, Haibo Ren, Lin Xu, Lianggeng Gong The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, China Impact: For the first time, this study reported the association of hemodynamics with myocardial fibrosis in ischemic and dilated cardiomyopathy patients, providing potential targets for anti-fibrotic treatment.