Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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563-02-001.
Normative T1 and T2 Relaxation Time Values of Healthy Knee Cartilage in a Single-Age, Population-Based Cohort
Impact: MRF-derived T1 and T2
mapping of knee cartilage established normative reference values for young
adults with radiologically healthy knees. Compartment- and depth-specific values
provide a benchmark for studying early cartilage degeneration and evaluating
preventive interventions for osteoarthritis.
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563-02-002.
Longitudinal quantitative MRI of cartilage degeneration in ACL-reconstructed patients using ultrashort echo time adiabatic T1
Impact: This study demonstrates that UTE
Adiabatic T1ρ MRI can sensitively detect early cartilage degeneration after ACL
reconstruction, enabling clinicians to monitor osteoarthritis risk
non-invasively and inspiring further research into early therapeutic interventions
and quantitative imaging biomarkers for joint health.
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563-02-003.
In vivo MR elastography reveals cartilage stiffness changes linked to altered gait patterns post-ACL surgery
Impact: Our findings enable MRI-based early detection of
cartilage stiffness changes post-ACL injury, offering clinicians a tool to
predict osteoarthritis onset.
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563-02-004.
Prediction of Cartilage Proteoglycan Content from MR Fingerprinting Using Deep Kernel Learning Gaussian Processes (DKL-GP)
Impact: Deep Kernel Learning Gaussian Processes (DKL-GP) offer accurate predictions of histological tissue properties from MR Fingerprinting (MRF) data. The work demonstrates the value of combining deep learning with probabilistic modeling
for tissue characterization from fast quantitative MRI.
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563-02-005.
Texture Cluster Analysis Of Knee Cartilage T2 Maps
Impact: GLCM texture clusters differ not only
between patients and healthy controls but also align spatially with lesion
locations. Clusters provide an intuitive visual representation that is easier
to interpret in clinical practice than numerical feature values from the entire
ROI.
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563-02-006.
Quantitative Susceptibility Mapping Reveals Layer-Specific Biomechanical Response in Knee Cartilage to Mechanical Loading
Impact: Our findings demonstrate unique spatiotemporal susceptibility patterns in knee cartilage collagen following mechanical loading.The observed temporal differences in medial versus lateral susceptibility changes may provide new insights for early osteoarthritis diagnosis.
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563-02-007.
Healthy knee cartilage T2 mapping assessed with GRAPPATINI and multi-echo spin-echo (MESE) at 3T
Impact: Quantitative cartilage MRI is faster, more
reliable, and clinically feasible with accelerated GRAPPATINI compared to conventional
multi-echo spin-echo sequence.
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563-02-008.
Longitudinal Quantitative MRI of Meniscal Degeneration in ACLR Patients Using 3D UTE-MT and UTE-Adiab-T1ρ Imaging
Impact: This
study highlights UTE-Adiab-T1ρ
and UTE-MMF as key tools for early, non-invasive detection of meniscal
degeneration post-ACLR, offering a promising approach to predict and mitigate
OA.
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563-02-009.
Feasibility and Repeatability of UTE-Adiabatic-T1ρ for whole-knee assessment
Impact: Adiabatic T₁ρ mapping using UTE
at 3T enables robust, repeatable, and field-insensitive tissue quantification.
Optimized TAN-based spin-lock pulses may enhance the sensitivity for early
musculoskeletal degeneration detection, advancing clinical diagnostics and
research in tissue relaxation imaging.
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563-02-010.
HRDNet: Hybrid ResNeXt–Dense Network for Quantitative T1ρ Mapping from Undersampled k-Space
Impact: HRDNet directly estimates T1ρ maps from accelerated, undersampled multi-coil k-space, improving fidelity and precision over common deep-learning baselines. Therefore, it advances translation toward routine clinical assessment of early osteoarthritis, moving quantitative knee MRI toward everyday practice.
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563-02-011.
Highly efficient simultaneous 3D joint T1-T2 mapping of the knee at 0.55T: Comparison of Cartesian and radial strategies.
Impact: This
work demonstrates the potential of low-field MRI for rapid quantitative
cartilage assessment, achieving simultaneous 3D T1 and T2 mapping of the knee
in under 4 minutes with two different acquisition strategies based on Cartesian
and radial imaging.
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563-02-012.
Quantitative MRI Characterization of Osteochondritis Dissecans Lesion Development in a Piglet Model
Impact: Quantitative
MRI captures multiple changes during the temporal evolution of OCD lesions, with
T2 and T2* detecting early injury, fat fraction demonstrating delayed marrow
remodeling, and DESS depicting late morphological disruption, thus providing noninvasive
methods to monitor OCD lesion development.
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563-02-013.
Does T₂ Fitting Model Impact Repeatability and Longitudinal Cartilage Repair Assessment?
Impact: This study
aims to improve qMRI interpretation in cartilage repair by clarifying how T₂
fitting models influence repeatability and longitudinal trends, supporting
development of robust imaging biomarkers and integration with clinical outcomes
for better patient monitoring.
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