Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

fMRI: Analyses

Back to the Program-at-a-Glance

fMRI: Analyses
Digital Poster
Brain Function & fMRI
Monday, 11 May 2026
Digital Posters Row E
08:20 - 09:15
Session Number: 364-01
No CME/CE Credit
This session covers state-of-the-art fMRI data analysis methods.
Skill Level: Basic

  Figure 364-01-001.  Self-Regulating AI Agent for End-to-End Multi-model MRI Diagnostic Analysis of Neurodegenerative Diseases
Xingyang Wu, Shuo Zhou, Isah Ahmad, Fanshi li, Yanjie Zhu, Yihang Zhou, Dong Liang, Zhanqi hu, Haifeng Wang
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
Impact: Creates a self-regulating loop from MRI reconstruction to diagnosis, establishing a new paradigm for intelligent imaging.
  Figure 364-01-002.  MeshD²R:Mesh-guided Dual-resolution Diffusion Reconstruction of Visual Stimuli from BOLD-fMRI Signals
liu ming, Shiyi Zhang, Qihui Ye, Shuo Zhou, Yihang Zhou, Dong Liang, Yanjie Zhu, Hairong Zheng, Haifeng Wang
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
Impact: This work enables more accurate visual decoding of brain activity, paving the way for new neuroscience research and future clinical technologies like communication aids for paralyzed patients.
  Figure 364-01-003.  Sensitivity and Specificity Comparison of Real-Time and Offline Resting-State fMRI Analysis Pipelines using ROC Analysis
Arthur Schoen, Logan Dowdle, Orrin Myers, Essa Yacoub, Stefan Posse
University of New Mexico, Albuquerque, United States of America
Impact: This study demonstrates that real-time rsfMRI analysis approaches the sensitivity and specificity of state-of-the-art offline analysis pipelines. Toolbox differences are dominated by differences in spatial co-registration that are sensitive to volume coverage.
  Figure 364-01-004.  Altered Neurovascular Coupling in Relation to Spatial Navigation in Subjective Cognitive Decline: Insights from 5.0Tesla MRI
Futao Chen, Lixian Zou, Jiaming Lu, Qian Chen, Yichen Wang, Bing Zhang
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
Impact: Our 5T MRI study identifies impaired neurovascular coupling and its association with spatial navigation deficits as a key early event in SCD. This provides a novel multimodal imaging marker to advance preclinical Alzheimer's detection and prevention.
  Figure 364-01-005.  Effect of Visual Task on Precuneus Sub-Region Metabolism Measured with Hyperpolarized [1-13C]-Pyruvate MRI
Shawna Pervin, Nicole Cappelletto, Biranavan Uthayakumar, Albert Chen, Ruby Endre, Nathan Ma, William Perks, Arjun Sahgal, Hany Soliman, Chris Heyn, Charles Cunningham
Sunnybrook Research Institute, Toronto, Canada
Impact: Evaluation of the metabolism of the sub-regions of the precuneus lays the foundation for the use of these regions as predictive biomarkers for diseases, such as Alzheimer’s disease, where hypometabolism in the precuneus is characteristic before the onset of symptoms.
  Figure 364-01-006.  Orbitofrontal TMS Engages Fronto-limbic Circuits Relevant to Depression: Evidence from interleaved TMS-fMRI
Minyan Huang, Michael Woletz, Severin Schramm, Maria Vasileiadi, Onisim Soanca, Anna-lisa Schuler, Jonathan Downar, Martin Tik
Medical University of Vienna, Vienna, Austria
Impact: AF8 and F8 are clinically used targets to treat depression with TMS, our work suggests F8 as a superior cortical entry point into lOFC-striatal circuit than AF8, informing precision targeting to enhance therapeutic efficacy in treatment-resistant depression.
  Figure 364-01-007.  Activation Spread due to Local Low-Rank Denoising in SMS-EPI Task-Based fMRI Data
Sofia Kardonik, Douglas Noll, Jeffrey Fessler
University of Michigan, Ann Arbor, United States of America
Impact: Low-rank denoising in fMRI improves sensitivity, but may also produce false positive activation spread. Understanding the effect of low-rank denoising can help researchers more accurately identify activation regions to interpret brain activity.
  Figure 364-01-008.  Neural-Behavioral Decoupling in Apathy in Parkinson's Disease: A Co-activation Pattern Study
Hao Li, Xuelian Zhao, Kai AI, Yao Liu, Jing Zhang
Department of Magnetic Resonance, Lanzhou, China
Impact: By revealing a complete brain-behavior decoupling, our work provides a systems-level perspective on PD apathy. This shifts the research focus from regional deficits to impaired neural communication as the ultimate cause.
  Figure 364-01-009.  Mapping Cerebrovascular Reactivity and Vascular Delay across Glioma Subregions Using Multi-Echo BOLD fMRI with Breath-holding
Cristina Comella Luengo, Lia Hocke, Stefano Moia, Santiago Gil Robles, Iñigo Pomposo, Manuel Carreiras, Ileana Quiñones, César Caballero-Gaudes
Basque Center on Cognition, Brain and Language, San Sebastian - Donostia, Spain
Impact: This study demonstrates the feasibility of assessing cerebrovascular reactivity and vascular delay in glioma using multi-echo BOLD-fMRI during breath-holds. While CVR reductions were detected within tumors, subregional differences were inconsistent, calling for improved methods and modeling of heterogenous vascular alterations
  Figure 364-01-010.  Safety Evaluation of Active Spinal Cord Stimulation During Brain fMRI on a Compact 3T MRI System
Lydia Bardwell Speltz, Seung-Kyun Lee, Afis Ajala, Eric Fiveland, Jianwei Qiu, Phillip Rossman, Benjamin Wilson, Yunhong Shu
Mayo Clinic, Rochester, United States of America
Impact: 
Our results indicate that compact 3T MRI system enables safe fMRI scanning with high-performance neuroimaging gradients in patients during active spinal cord stimulation, representing a significant step toward broader imaging access and real-time evaluation of neuromodulation therapies.
  Figure 364-01-011.  A modified white-matter and CSF regression approach for better physiological denoising in resting-state fMRI.
Ali Golestani, J. Jean Chen
University of Calgary, Calgary, Canada
Impact: This study introduces a data-driven fMRI denoising method that accounts for time delays in physiological signal propagation through white matter (WM) and cerebrospinal fluid (CSF). The approach outperformed conventional WM-CSF regression and aCompCor, enhancing the accuracy of resting-state fMRI analysis.
  Figure 364-01-012.  Neurofunctional dysregulations in nonsuicidal self-injury and suicide attempt: an fMRI meta-analysis
Xiqin Liu, Lu Tang, Yuanyuan Li, Nanfang Pan, Jianyu Li, Jian Zhou, Benjamin Becker, Qiyong Gong
Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China
Impact: This meta-analysis reveals separable brain activation patterns distinguishing nonsuicidal self-injury from suicide attempts, suggesting they arise from distinct neurobiological dysfunctions rather than representing a behavioral continuum. These findings highlight the potential of neuroimaging biomarkers for differential diagnosis and personalized interventions.
  Figure 364-01-013.  A deep-learning model to enhance the quality and fidelity of resting-state cerebrovascular reactivity quantification
Ali Golestani, J. Jean Chen
University of Calgary, Calgary, Canada
Impact: This study introduces a deep learning approach that enhances cerebrovascular reactivity (CVR) maps derived from resting-state fMRI, making them comparable to standard CO2-based methods. This improvement could enable broader and easier assessment of vascular brain health without gas-delivery equipment.
  Figure 364-01-014.  Integrated Macro- and Microstructural Gradients Reveal Complementary Contributions to Cortical Functional Hierarchy
Paween Wongkornchaovalit, Tianyong Xu, Jingcheng Wang, Jintao Wei, Yahong Chen, Junye Yao, Bingchen Shao, Lu Han, Hongjian HE
Zhejiang University, Hangzhou, China
Impact: Integration of macro- and microstructural metrics provides complementary cortical characterization. The unified macro–micro structural gradients align with functional organization, revealing complementary contributions from diffusivity, morphology, and anisotropy, and establishing a framework extendable to neurodegenerative and psychiatric disorder studies.

Back to the Program-at-a-Glance

© 2026 International Society for Magnetic Resonance in Medicine