Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Traditional Poster

Preclinical

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Preclinical
Traditional Poster
Preclinical
Wednesday, 13 May 2026
Traditional Posters | Exhibition Hall
16:00 - 16:55
Session Number: 570-08
No CME/CE Credit
Preclinical MRI of various Organs in experimental models and phantoms
Skill Level: Basic

  Figure 570-08-220.  Near-Field Coupling wireless coils for 9.4T Rat Head MRI Paired with a Birdcage Coil: A comparative study
Zhuoyang Lin, Ganghan Yang, Wei Cao, Wenhao Liao, Peiyu He, Feng Du, Nan Li, Zhiguang Mo, Qiaoyan Chen, Xiaoliang Zhang, Ye Li
Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
Impact: This study validates near-field-coupled(NFC) wireless surface coils for rat brain MRI at 9.4 T through comparative experiments using a birdcage coil(BC). The result demonstrates wireless multiple loop coil arrays provide superior image coverage/depth, and sensitivity, aiding small animal coil design.
  Figure 570-08-221.  Evaluation of Cerebral Blood Flow Dynamics in Rat Brain Using Phase-Contrast MRI
kamel abderrahim, Sidy Fall, Olivier Baledent
Université de Picardie Jules Verne (UPJV), Amiens, France
Impact: This study demonstrates the feasibility of non-invasive quantification of cerebral arterial inflow and venous outflow in rats using phase-contrast MRI. It provides new insight into cerebrovascular coupling, physiological variability, and technical challenges in preclinical hemodynamic imaging.
  Figure 570-08-222.  Reliability of Dental-Dedicated Ultrashort Echo Time MRI for Visualization of Mandibular Anatomy in ex vivo Human Specimens
Karen Kettless, Gabriela Salatino Liedke, Stefan Sommer, Rubens Spin-Neto
Siemens Healthcare A/S, Ballerup, Denmark
Impact: This study demonstrates the feasibility of dental-dedicated MRI (ddMRI) using ultra-short echo time (UTE) research application sequence for high-resolution imaging of mandibular anatomy, allied to the fact that preservation conditions significantly influenced image quality.
  Figure 570-08-223.  Neurometabolic similarity matrix to study metabolic connectivity in chronic hepatic encephalopathy: a preliminary study
Thi Ngoc Anh Dinh, Gianna Nossa, Tan Toi Phan, Federico Lucchetti, Valerie McLin, Paul Klauser, Cristina Cudalbu
CIBM Center for Biomedical Imaging, Lausanne, Switzerland
Impact: This preliminary data suggests disrupted interregional metabolic coordination in the BDL rat model of chronic hepatic encephalopathy, revealing network-level metabolic dysfunctions and highlighting the potential of MRSI-based approaches for translational biomarker discovery.
  Figure 570-08-224.  Validation of anisotropic diffusion at 5T using a hollow fiber phantom
Robert Welsh, Kate Fissell, Guangyu Dan, Qi Liu, Peter Martin, Anthony Zuccolotto, Walter Schneider
University of California Los Angeles, Los Angeles, United States of America
Impact: Demonstrating that ground truth phantom physical parameters are accurately estimated at 5.0T is a necessary step towards quantitative MRI in humans.
  Figure 570-08-225.  Investigating the effect of focused ultrasound on relaxation and oxygenation in an intracerebral haemorrhage stroke rat model
Fabian Küppers, Ezequiel Farrher, Kuan-Hung Cho, Sheng-Min Huang, Yi-Hua Hsu, Ming-Jye Chen, Chia-Ching Pan, Hsin-Yun Chang, Chang-Hoon Choi, N. Jon Shah, Abel Po-Hao Huang, Gin-Shin Chen, Li-Wei Kuo
Forschungszentrum Juelich, Juelich, Germany
Impact: Additional multi-echo GE acquisition with T2 quantification on an ICH stroke rat model utilising FUS application enables OEF estimates. Baseline MR parameters in the cortical region agree with previous results, and OEF increases following the application of FUS stimulation.
  Figure 570-08-226.  In Vivo MRI Reveals Melatonin Alleviates Hypoxic-Ischemic Brain Damage by Suppressing TXNIP/Trx-1/GPX4-Mediated Ferroptosis
Xiaoli Wang, Youcheng Qin, Peilun Xiao, Xinyue Zhang, Xiaozu Zhang, Haimo Zhang, Yijing Wang, Miao Yu, Peng Wu
Shandong Second Medical University, Weifang, China
Impact: This study identifies melatonin as a promising therapy for neonatal brain injury and validates the TXNIP/Trx-1/GPX4 axis as a key target, enabling future clinical trials and the use of MRI for non-invasive treatment monitoring.
  Figure 570-08-227.  A Preclinical Susceptibility Phantom for Quantitative Evaluation of QSM Algorithms in the Rat Brain
Belal TAVASHI, Leen HAKKI, Esin Ozturk Isik, Pinar Özbay
Boğaziçi University Institute of Biomedical Engineering, Istanbul, Turkey
Impact: Phantoms enable optimization of preprocessing algorithms, because reference values are known and used to evaluate performance. This helps answer questions like what algorithm works best for a specific organism, how do various factors affect performance and how to overcome hurdles.
  Figure 570-08-228.  Effects of modifiable dementia risk factors on brain metabolism and structure through multimodal MRI in transgenic mice
Gianmauro Palombelli, Valentina Zecca, Gabriele De Luca, Valeria SImonelli, Paola Piscopo, Federica Perrone, Alessio Crestini, Laura Ricceri, Nicola Vanacore, ROSSELLA CANESE
Istituto Superiore di Sanità, Rome, Italy
Impact: Our results demonstrate that modifiable risk factors for dementia can influence brain metabolism and structure. These changes can be monitored non-invasively using multimodal MRI. These findings may inform the design of future clinical trials and support public health intervention strategies.
  Figure 570-08-229.  Multiparametric mapping of tumor hypoxia in a human neuroendocrine tumor mouse model
Mikael Montelius, Lukas Lundholm, Maja Sohlin, Oscar Jalnefjord, Eva Forssell-Aronsson, Maria Ljungberg
University of Gothenburg, Gothenburg, Sweden
Impact: This work will contribute to the development of new, non-invasive imaging tools for characterization, therapeutic decision making and therapy response assessment in hypoxic solid cancers, which are associated with poor prognosis, radiation therapy resistance and metastatic disease.

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