Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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570-08-220.
Near-Field Coupling wireless coils for 9.4T Rat Head MRI Paired with a Birdcage Coil: A comparative study
Impact: This study validates
near-field-coupled(NFC) wireless surface coils for rat brain MRI at 9.4 T
through comparative experiments using a birdcage coil(BC). The result
demonstrates wireless multiple loop coil arrays provide superior image coverage/depth,
and sensitivity, aiding small animal coil design.
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570-08-221.
Evaluation of Cerebral Blood Flow Dynamics in Rat Brain Using Phase-Contrast MRI
Impact: This study demonstrates the feasibility of non-invasive
quantification of cerebral arterial inflow and venous outflow in rats using phase-contrast MRI. It provides new insight into cerebrovascular coupling,
physiological variability, and technical challenges in preclinical hemodynamic
imaging.
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570-08-222.
Reliability of Dental-Dedicated Ultrashort Echo Time MRI for Visualization of Mandibular Anatomy in ex vivo Human Specimens
Impact: This study demonstrates the
feasibility of dental-dedicated MRI (ddMRI) using ultra-short echo time (UTE) research
application sequence for high-resolution imaging of mandibular anatomy, allied
to the fact that preservation conditions significantly influenced image quality.
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570-08-223.
Neurometabolic similarity matrix to study metabolic connectivity in chronic hepatic encephalopathy: a preliminary study
Impact: This preliminary data suggests disrupted interregional metabolic coordination in the BDL rat model of chronic hepatic encephalopathy, revealing network-level metabolic dysfunctions and highlighting the potential of MRSI-based approaches for translational biomarker discovery.
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570-08-224.
Validation of anisotropic diffusion at 5T using a hollow fiber phantom
Impact: Demonstrating that
ground truth phantom physical parameters are accurately estimated at 5.0T is a
necessary step towards quantitative MRI in humans.
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570-08-225.
Investigating the effect of focused ultrasound on relaxation and oxygenation in an intracerebral haemorrhage stroke rat model
Impact: Additional
multi-echo GE acquisition with T2 quantification on an ICH stroke rat
model utilising FUS application enables OEF estimates. Baseline MR parameters in
the cortical region agree with previous results, and OEF increases following the
application of FUS stimulation.
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570-08-226.
In Vivo MRI Reveals Melatonin Alleviates Hypoxic-Ischemic Brain Damage by Suppressing TXNIP/Trx-1/GPX4-Mediated Ferroptosis
Impact: This study identifies melatonin as a promising therapy for neonatal brain injury and validates the TXNIP/Trx-1/GPX4 axis as a key target, enabling future clinical trials and the use of MRI for non-invasive treatment monitoring.
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570-08-227.
A Preclinical Susceptibility Phantom for Quantitative Evaluation of QSM Algorithms in the Rat Brain
Impact: Phantoms enable optimization of preprocessing algorithms, because reference values are known and used to evaluate performance. This helps answer questions like what algorithm works best for a specific organism, how do various factors affect performance and how to overcome hurdles.
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570-08-228.
Effects of modifiable dementia risk factors on brain metabolism and structure through multimodal MRI in transgenic mice
Impact: Our results
demonstrate that modifiable risk factors for dementia can influence brain
metabolism and structure. These changes can be monitored
non-invasively using multimodal MRI. These findings may inform the design of
future clinical trials and support public health intervention strategies.
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570-08-229.
Multiparametric mapping of tumor hypoxia in a human neuroendocrine tumor mouse model
Impact: This work
will contribute to the development of new, non-invasive imaging tools for characterization,
therapeutic decision making and therapy response assessment in hypoxic solid cancers,
which are associated with poor prognosis, radiation therapy resistance and
metastatic disease.
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