Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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562-05-001.
Multi-Organ Volumetric Growth Trajectories in Fetuses with Hydronephrosis
Impact: In this case-control study,
hydronephrotic fetuses exhibited significant renal pelvis dilation and increased
brain, liver and placental volumes, suggesting potential impact of
hydronephrosis on global fetal development.
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562-05-002.
Early Music Exposure Enhances Claustrum Microstructural Maturation in Preterm Infants: Evidence from Diffusion MRI
Impact: We demonstrate that early structured music exposure may accelerate claustrum maturation in preterm infants, enhancing its microstructural organization. These findings highlight music as a promising, non-invasive intervention to support subcortical development and mitigate neurodevelopmental vulnerabilities associated with premature birth.
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562-05-003.
RF Safety Evaluation of Infant Neuroimaging at 5.0 T
Impact: This study provides the first quantitative evidence that 5 T infant neuro-MRI can be performed safely, supporting clinical translation of ultra-high-field systems and informing sequence optimization and RF-safety supervision for pediatric imaging.
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562-05-004.
Quantitative MRI Biomarkers Reveal Spatiotemporal Patterns of Fetal Adipose Tissue Development and Brown-to-White Fat Convers
Impact: This study provides novel insights into
the spatiotemporal dynamics of fetal adipose tissue development and the
transition from brown adipose tissue to white adipose tissue, which helps early identification
and precision management of metabolic health risks during fetal development.
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562-05-005.
Development of Structure-Function Coupling in the Very Preterm Newborn Brain and Effects of Early Music Exposure
Impact: Structure-function relationship matures during preterm
development towards adult-like patterns through term-equivalent-age. This
maturation exceeds that of full-term infants, and is further enhanced by early
music exposure, suggesting early environmental impacts on structure-function
maturation.
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562-05-006.
Towards real-time navigation in diagnostic fetal brain MRI
Impact: We present a feedback loop system for automated prescription of imaging slices that account for the fetal head motion in real time. This work promises to significantly improve radiological assessments, reduce scan time, and alleviate pregnant patients’ discomfort.
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562-05-007.
White Matter Development Following Maternal Iron Supplementation: A Diffusion MRI Study of Intravenous versus Oral Iron
Impact: This study provides evidence that maternal iron supplementation formulation influences infant white matter microstructural development. Findings suggest intravenous iron supplementation may optimize iron delivery during critical neurodevelopmental periods, informing clinical guidelines for managing iron deficiency in vulnerable populations worldwide.
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562-05-008.
Clinical Feasibility of NeSVoR 3D Fetal Brain Reconstruction Across Realistic Fetal Motion
Impact: This study validates NeSVoR using real in vivo fetal motion, filling gaps left by synthetic motion tests. It quantifies reconstruction stability across clinical motion intensities, advancing algorithm generalizability, guiding MRI acquisition, and ensuring reliable fetal brain imaging for clinical use.
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562-05-009.
Lac/NAA Ratio Threshold Using sLASER-144 Single-Voxel MRS and ADC Scores in Neonates with Hypoxic-Ischemic Encephalopathy
Impact: Early follow-up–based
Lac/NAA cutoffs from sLASER-144 MRS provide neonatologists with greater
certainty, as elevated ratios can confirm metabolic brain injury. When used
alongside ADC values, Lac/NAA serves as a complementary parameter to improve
prognostic accuracy and guide early interventions.
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562-05-010.
T2* based Functional Mapping of the neonatal brain using Echo Planar Time-resolved Imaging at 7 Tesla
Impact: We demonstrate task-elicited changes in T2* using EPTI at ultra-high field in infants for the first time. This more quantitative functional measurement enables robust inter-subject analysis and can advance understanding of early neonatal neurovascular development.
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562-05-011.
Diffusion Tensor MRI Thermometry in Preterm Neonates: Validation of a CSF-Based Model Toward Fetal Temperature Estimation
Impact: We demonstrated the first phase of validation of fetal diffusion-based
thermometry using preterm CSF, a surrogate for fetal CSF. This can facilitate the transition to fetal diffusion-based thermometry and future noninvasive quantitative monitoring of fetal temperature, thereby enhancing fetal-maternal safety.
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562-05-012.
First in-vivo brain MRI of an awake infant on a compact helium-free 1.5T pediatric scanner
Impact: Bedside MRI of awake infants is
feasible using the compact helium-free 1.5T pediatric scanner. Diagnostic image
quality without sedation enables safe, flexible neuroimaging directly next
to pediatric ICU, reducing transport risks and
expanding access to radiation-free imaging in vulnerable patients.
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562-05-013.
First External Validation of Automated Slice-to-Volume Reconstruction and Automated Lung Volumetry in Fetal MR Imaging
Impact: The clinical
validation of automated pipelines for accurate slice-to-volume reconstruction,
lung segmentation and volumetry of motion-corrupted fetal MRI-scans,
demonstrated here in 37 cases, is a crucial step to identify the potential of
the inclusion of these pipelines in clinical workflows.
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562-05-014.
GABA Measurements with and without Macromolecule Suppression in the Neonatal Brain
Impact: To
our knowledge, this
is the first study to report co-edited macromolecules that contaminate GABA+
measurements using MEGA-PRESS in the neonatal brain. Results offer a better
understanding of the severity of co-editing impact and provide insight into developing
correction methods.
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562-05-015.
Multi-echo spiral acquisition for rapid, sub-millimetre neonatal R2* whole brain mapping at 7T
Impact: This study demonstrates rapid, sub-millimetre neonatal R2* mapping at 7T using multi-echo spiral imaging. The method enables whole-brain quantitative mapping within minutes, advancing ultra-high field neonatal MRI for studying early brain microstructure and developmental or pathological alterations.
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© 2026 International Society for Magnetic Resonance in Medicine