Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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369-03-001.
Lateralized Neurovascular-Glymphatic Imbalance and Cognitive Heterogeneity in Mild Ischemic Stroke: A Multimodal MRI Study
Impact: Lateralized glymphatic-neurovascular dysfunction after mild ischemic stroke opens new avenues for mechanistic studies, facilitates exploration of region-specific cognitive decline, and advances the application of multimodal imaging for monitoring functional clearance and intervention efficacy.
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369-03-002.
Multiparametric CEST MRI and pH Mapping in Acute and Chronic Ischemic Stroke: Preliminary Clinical Findings
Impact: Multiparametric CEST MRI and pH mapping effectively delineated acute
stroke lesions and differentiated chronic stroke groups, correlating with onset
time and clinical severity. These findings highlight the potential of CEST MRI as
a non-invasive biomarker for stroke diagnosis and management.
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369-03-003.
Cerebral Vascular Burden Disrupts the Structural-Functional Gradient of Human Brain: A Multi-modal Brain MRI Study
Impact: This study reveals how vascular injury
disrupting brain structure-function coupling, offering new insights into our understanding on cognitive decline. It enables future research into targeted
interventions and network-specific vulnerability in cerebrovascular disease.
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369-03-004.
Microstructural Alterations of Normal Appearing White Matter Assessed by Quantitative Multiparametric Mapping
Impact: By detecting early, not yet visible microstructural changes in the NAWM, qMPM could contribute to gaining insights into the dynamics of WMH changes and associated potential therapeutic interventions.
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369-03-005.
Leiden Clustering-driven Radiomic Superpixels Decode Spatial Heterogeneity In Multimodal Stroke MRI
Impact: This study introduces a novel radiomics-based clustering framework leveraging multimodal MRI to delineate spatial brain heterogeneity in acute ischemic stroke, enabling precise prognosis prediction. It may help clinicians stratify patient risk, personalize treatment, and inspire new imaging biomarkers for stroke.
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369-03-006.
IVIM-Derived Microvascular Reserve Predicts Tissue Salvageability Within the Perfusion-Diffusion Mismatch in Acute Stroke
Impact: This work introduces a non-contrast MRI biomarker that directly reflects microvascular tissue viability,enabling more accurate identification of salvageable penumbra. It may improve reperfusion treatment decisions,particularly in patients with unclear onset or contrast contraindications, supporting more personalized and safer stroke care.
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369-03-007.
Multimodal MRI Tracks Synergistic Neurovascular Repair with MSC-Exosomes and Low-Intensity Pulsed Ultrasound after Rat MCAO
Impact: Multimodal MRI yields sensitive biomarkers—relative ADC (rADC), IVIM perfusion fraction (f) and pseudo-diffusion (D*), and relative CBF (rCBF)—that capture synergistic neurovascular repair from MSC-exosomes plus LIPUS, enabling earlier response read-outs and facilitating preclinical-to-clinical translation in ischemic stroke.
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369-03-008.
Discriminating Etiological Subtypes of Acute Ischemic Stroke Using a Dual-Center Integrated Clinical-Radiomics Model
Impact: This validated model provides clinicians with an objective decision-support tool for refining TOAST subtyping between SAO and CE, addressing a key diagnostic challenge. It paves the way for investigating the model's impact on specific patient management decisions and long-term outcomes.
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369-03-009.
Prior-Guided Diffusion Model for High-Fidelity Multi-Modal VWI Synthesis in Ischemic Stroke
Impact: This prior-guided diffusion framework enables rapid generation
of multi-contrast VWI from a single acquisition, potentially reducing scan time
and patient burden while preserving diagnostic integrity for cerebrovascular
assessment.
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369-03-010.
Prediction of 10-year infarction cardiovascular diseases risk using multimodal model and interpretability methods
Impact: Our model identifies individuals at high infarction-related CVD risk in 10 years, aiding clinicians in personalized health monitoring guidance.
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369-03-011.
Predicting Hemorrhagic Transformation after Stroke Thrombolysis by Integrating MRI Radiomics with Clinical Risk Factors
Impact: This study established a comprehensive predictive
model that enables personalized thrombolysis risk assessment by integrating
clinical and radiomic data, permitting early identification of high-risk AIS
patients for optimized treatment strategies.
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369-03-012.
Development of an Ischemic Stroke Risk Prediction Model in Patients with Intracranial Atherosclerosis Based on Multimodal MRI
Impact: The nomogram integrating HR-MRI plaque characteristics with ASL imaging to discriminate 1.5s-ATA and 2.5s-ATA presence accurately predicts ischemic stroke in ICAS, supporting risk stratification for stroke decision-making.
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369-03-013.
Multi-parametric Metabolic Profiling in Ischemic Stroke Using 5T CEST-MRI with Advanced Quantitative Analysis (CESTQuant)
Impact: This work establishes a robust, standardized framework for multi-parametric metabolic imaging using 5T CEST-MRI, providing unprecedented insights into the cerebral metabolic microenvironment after stroke and enabling future clinical translation.
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369-03-014.
Associations between Structural and Functional Measures of Bilateral Motor Network Changes and Motor Recovery After Stroke
Impact: Mapping
primary motor cortex status and interhemispheric balance during stroke recovery
may identify key drivers of motor improvement, which could guide targeted
interventions to accelerate stroke rehabilitation in patient clinics.
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© 2026 International Society for Magnetic Resonance in Medicine