Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition

Metabolic Parameters in Stroke

Digital Poster

Neuro A

Tuesday, 12 May 2026

Digital Posters Row D

13:40 - 14:35

Session Number: 463-03

No CME/CE Credit

Similar Sessions

This digital poster session comprises a comprehensive range of clinical MRI methods, aiming to understand metabolic parameters in ischemic stroke, such as perfusion, hemodynamic parameters, cerebrovascular reactivity, and oxygenation, utilising the state-of-the-art and leading-edge approaches.

		463-03-001. Multi-echo fMRI improves breath-hold BOLD cerebrovascular reactivity estimates in stroke Rebecca Clements, Fatemeh Geranmayeh, Niamh Parkinson, Molly Bright Northwestern University, Chicago, United States of America Impact: These results highlight the benefits of a multi-echo fMRI protocol for improved CVR characterization and support its translation into clinical practice, potentially enabling personalized stroke rehabilitation strategies and improved prediction of recurrent stroke risk.
		463-03-002. Oxygenation and Perfusion Pattern of Grey Matter and White Matter in Ischemic Stroke Di Wu, Changliang Su, Jiayu Fang, Zuwu Ai, Junxiong Xie, Yaqin Zhang, Wenzhen Zhu The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China Impact: Oxygenation and perfusion pattern estimated by MRI showed similarity and discrepancy between grey matter and white matter in ischemic stroke, indicating different neuropathology and prognostic value.
		463-03-003. Macrovascular Arterial Transit Time from 4D ASL-MRA: A Novel Hemodynamic Biomarker in Intracranial Steno-Occlusive Disease Quinten Deckers, Simone Uniken Venema, Pieter Deckers, Kees Braun, Bart van der Zwan, Jeroen Siero, Alex Bhogal UMC Utrecht, Utrecht, Netherlands Impact: Macrovascular arterial transit time (mATT) proved sensitive to cerebrovascular changes after vasodilation and revealed key pathological abnormalities, highlighting its potential as a noninvasive hemodynamical biomarker for tracking disease progression and guiding management of patients with intracranial steno-occlusive disease.
		463-03-004. Reduced Structural and Perfusion Alterations with Smaller Lesion Volume after Ischemia-Reperfusion Injury in FKBP51 Knockout Sih-Ting Chen, Chia-Feng Lu, Yu-Chieh Jill Kao National Yang Ming Chiao Tung University, Taipei, Taiwan Impact: This study reveals FKBP51 as a genetic determinant of ischemic lesion development. The findings may inspire new research on molecular mechanisms of ischemic resilience, advancing precision diagnosis and individualized stroke treatment strategies.
		463-03-005. Early Changes in Oxygen-Metabolism Biomarkers Predict Long-Term Recovery in Ischemic Stroke Patients Tian Qiu, Quinn Boyer, Di Wu, Guiling Zhang, Shun Zhang, Junghun Cho George Washington University, Washington, United States of America Impact: This study demonstrated that QQ-based OEF and CMRO₂ maps can serve as biomarkers for predicting ischemic stroke recovery in the early stage after stroke onset, enabling clinicians to incorporate early OEF and CMRO₂ measurements into treatment decisions.
		463-03-006. Diagnostic accuracy of ultra-low-field MRI for strokes in the anterior circulation depending on infarct size and location Julian Sauer, Dimah Hasan, Konstantin Ueffing, Annika Rieder, Clara Heller, Frederic de Beukelaer, Jule Deiters, Jörg Schulz, Johannes Schiefer, Stefanie Kammer, Manuel Dafotakis, Martin Wiesmann, Florian Holtbernd, Charlotte Weyland RWTH Aachen University Hospital, Aachen, Germany Impact: Acute infarct evaluation in the anterior circulation with ultra-lowfield portable MRI (ULF-pMRI) has a different diagnostic accuracy depending on the location and volume of the infarct. Detection rate of small infarcts and infarcts in deep brain areas is limited.
		463-03-007. The hyperintensity vessel sign in intracranial atherosclerotic disease reflects the status of cerebral hemodynamics Feng Ouyang, Xianjun Zeng The First Affiliated Hospital of Nanchang University, Nanchang，Jiangxi, China Impact: Our study found hyperintensity vessel sign score on high-resolution magnetic resonance vessel wall imaging (HR-VWI) can reflect the degree of cerebral perfusion impairment, suggesting that HR-VWI can identify the risk of cerebral ischemia in patients with intracranial atherosclerotic stenosis.
		463-03-008. Imaging of Capillary and Venous Blood Transit in Sickle Cell Anemia Wesley Richerson, Megan Aumann, Alexander Song, Samantha Davis, Lauren Milner, Taylor Davis, Dann Martin, Lori Jordan, Manus Donahue Vanderbilt University Medical Center, Nashville, United States of America Impact: Findings are consistent with shortened capillary residency times in hemolytic anemia, which could provide a new biomarker of ischemia risk in sickle cell anemia patients.
		463-03-009. Clinical Utility of SWI-EPI for Penumbra Estimation using SWI–DWI Mismatch and its Comparison with ASL–based PWI–DWI Mismatch Ankit Kandpal, Rakesh Singh, Shalini Sharma, Rakesh Kumar Gupta, Anup Singh Indian Institute of Technology, Delhi, India Impact: EPI-based SWI demonstrates strong agreement with ASL-based perfusion in identifying the hypoperfused regions in acute ischemic strokes. Its ability to capture microvascular oxygenation changes through endogenous susceptibility contrast highlights its potential as a rapid, non-contrast alternative for penumbra estimation.
		463-03-010. Cerebral metabolism changes after successful reperfusion in ischemic stroke patients Victoria Mercy Kataike, Patricia Desmond, Christopher Steward, Bruce Campbell, Felix Ng, Vijay Venkatraman University of Melbourne, Melbourne, Australia Impact: Cerebral metabolic rate of oxygen, obtained with clinically adaptable MRI methods may be utilised to uncover novel pathophysiological insight in infarct evolution and recovery in ischemic stroke patients.
		463-03-011. Imaging Infarct Progression, Penumbra, and Future Infarction using IVIM MRI in Stroke Mira Liu, Robert King, Zeynep Vardar, Josephine Kolstad, Anna Kuhn, Vania Anagnostakou, Christopher Raskett, Jonathan Winger, Ana Krtolica, Nils Henninger, Matthew Gounis, Mohammed Salman Shazeeb Icahn School of Medicine at Mount Sinai, New York, United States of America Impact: Acute ischemic stroke perfusion imaging is relevant to treatment decisions by showing if regions of the brain parenchyma are salvageable. IVIM could simultaneously capture perfusion/diffusion for penumbra and core infarct to predict future infarct development in acute ischemic stroke.
		463-03-012. Mapping Cerebrovascular Reactivity: Comparison of Gradient Echo and Spin Echo BOLD with Arterial Spin Labelling Sara Pomante, Davide Di Censo, Alessandra Caporale, Fabrizio Fasano, DOMENICO ZACA', Elizabeth Fear, Francesca Graziano, Manuela Carriero, Giulia Rocco, Lucie Chalet, Emma Biondetti, Maria Eugenia Caligiuri, Michael Germuska, Richard Wise, Antonio Chiarelli University 'G.d'Annunzio' of Chieti-Pescara, Chieti, Italy Impact: The new sequence acquisition on healthy subjects shows that SE-BOLD fMRI may deliver a marker of CVR that resembles the ASL-derived physiological CVR more closely than CVR_GE-BOLD, with the advantage of high signal-to-noise ratio compared to ASL.
		463-03-013. Whole-Head Simulation of Thermal-Metabolic Feedback Effects on Cellular Function and Intracellular Na During Ischemic Stroke Douglas Brantner, Christopher Collins, Giuseppe Carluccio, Thomas Ventimiglia, Andreas Linninger, seena Dehkharghani Center for Advanced Imaging Innovation and Research (CAI²R), New York University Grossman School of Medicine, New York, United States of America Impact: A multi-physics, multi-scale model of ischemic stroke can provide insight into cellular-level metabolite dynamics as affected by ischemia and associated exacerbating inter-dependent effects of local temperature increase.
		463-03-014. Global and local arterial input functions for DSC MRI using physics-guided neural network with recirculation modeling HyoSeok Lee, Muhammad Asaduddin, Eung Yeop Kim, Sung-Hong Park Korea Advanced Institute of Science & Technology, Daejeon, Korea, Republic of Impact: The physics-guided neural network trained with large-scale simulations based on a physiologically realistic model provides both global and various local arterial input functions (AIFs) automatically with no manual selection, achieving higher accuracy and more robust physiological interpretation.
		463-03-015. The impact of reperfusion onset on QQ-derived oxygen metabolism in experimental ischemic stroke Bart Franx, Annette Van der Toorn, Lois Chin Joe Kin, Gene Kim, Yi Wang, Junghun Cho, Rick Dijkhuizen UMC Utrecht, Utrecht, Netherlands Impact: Reestablishment of brain oxygen metabolism may be a key predictor of ischemic stroke outcome after reperfusion therapy. We aim to demonstrate feasibility of new MRI-derived oxygen extraction fraction (OEF) estimation methods in an experimental stroke model while addressing this topic.