Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Flash Presentation

Quantitative Imaging: Applications

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Quantitative Imaging: Applications
Flash Presentation
Acquisition & Reconstruction
Wednesday, 13 May 2026
Roof Terrace
08:20 - 09:56
Moderators: Dana Peters & Matteo Cencini
Session Number: 531-01
CME/CE Credit Available
This session covers the new developments in quantitative MRI pulse sequences.

08:20 Figure 531-01-001.  MRI in Clinical Practice: Integrating ASL Perfusion and MRE Stiffness for Innovative Functional–Structural Assessment of CKD
Magna Cum Laude
Yueyao Chen, Peiyin Luo, Youjia Zeng, Ruirui Qi, Junfeng Li, Qiuyi Chen, Fanqi Meng, Hao dong Qin, Hanqing Lv
Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China
Impact: Combined ASL perfusion and MRE stiffness MRI enables integrated functional–structural evaluation of renal injury in CKD, improving diagnostic accuracy and allowing potential differentiation between reversible hypoperfusion and irreversible fibrosis for individualized clinical decision-making.
08:22 Figure 531-01-002.  Open Source CEST-MRI using BART: Sequence Definition, Reconstruction and Quantification
Markus Huemer, Daniel Mackner, Moritz Blumenthal, Sarah Warger, Philip Schaten, Clemens Stilianu, Martin Uecker, Rudolf Stollberger
Graz University of Technology, Graz, Austria
Impact: Providing open-source implementations of CEST-MRI sequences, reconstruction and quantification methods will enable researchers to reproduce the presented results including data acquisition. Additionally, new ideas can be implemented and tested with ease, leading to faster advancements in CEST-MRI methods development.
08:24 Figure 531-01-003.  From Ellipse to Projection Matrix: Perspective Geometry for Quantitative bSSFP Modeling
Magna Cum Laude
Haotian Hong, Yiyun Dong, Michael Hoff, Zijian Zhou, Peng Hu
ShanghaiTech University, Shanghai, China
Impact: Recasting bSSFP ellipses as perspective projections enables linear, voxel-wise estimation of tissue and field parameters from very few phase cycles, improving robustness to phase/coil errors and revealing a new geometric insight into bSSFP signal formation.
08:26 Figure 531-01-004.  Predicting Full-Dose Gadolinium T1 and T2 Maps from Low-Dose Multiparametric Acquisitions
Unay Dorken Gallastegi, Yohan Jun, Yuting Chen, Xingwang Yong, Camilo Calixto, Sergio Valencia, Shohei Fujita, Patricia Grant, Seonghwan Yee, Jason Stockmann, Borjan Gagoski, Camilo Jaimes, Berkin Bilgic
Harvard Medical School, Boston, United States of America
Impact: This method enables accurate full-dose-like qMRI mapping from low-dose Gd scans, reducing patient exposure to potentially harmful contrast agents. It allows safer, quantitative imaging and opens new avenues for low-dose MRI applications in both clinical practice and research.
08:28 Figure 531-01-005.  Measuring CBF, CSF pulsation and meningeal lymphatic flow in the head-down tilt position with pCASL and IR-ALADDIN
Minjae Kim, Jae-Geun Im, Sung-Hong Park
Korea Advanced Institute of Science & Technology, Daejeon, Korea, Republic of
Impact: This study provides the first evaluation of cerebral blood flow, cerebrospinal fluid pulsation, and meningeal lymphatic flow under head-down tilt, offering new insights into posture-induced intracranial fluid dynamics and a potential MRI framework to model microgravity-related physiological changes.
08:30 Figure 531-01-006.  Longitudinal Stability of 3D-MR Fingerprinting in Clinical Patient Populations
Andrew Dupuis, Robin Ghotra, Egheoise Otaigbe, Mark Griswold, Chaitra Badve, Rasim Boyacioglu
Case Western Reserve University, Cleveland, United States of America
Impact: Quantitative MRI requires clinical validation beyond controlled volunteer studies. We demonstrate 3D-MRF stability in real-world clinical environments by analyzing repeat examinations within 120 days, using manual ROI analysis to isolate stable regions from pathological changes.
08:32 Figure 531-01-007.  A Physics-Driven Neural Network with Parameter Embedding for Generating Quantitative MR Maps from Weighted Images
Lingjing Chen, Yinqiao Yi, Yang Song, Xu Yan, Shengfang Xu, Dalin Zhu, Mengqiu Cao, Yan Zhou, Chenglong Wang, Guang Yang
East China Normal University, Shanghai, China
Impact: Integrates acquisition physics into deep learning for robust qMRI generation, promoting reproducible and standardized quantitative imaging.
08:34 Figure 531-01-008.  High-Resolution 2D Cardiac MR Fingerprinting for Atrial Wall Assessment
Ana Cecilia Saavedra Bazan, Sydney Kaplan, Zhongnan Liu, Jacob Richardson, Chaitanya Madamanchi, Jesse Hamilton, Nicole Seiberlich
University of Michigan, Ann Arbor, United States of America
Impact: High-resolution MR Fingerprinting enables simultaneous quantitative T1 and T2 mapping in the thin atrial walls, opening new avenues for research and advancing our ability to noninvasively characterize atrial tissue properties.
08:36 Figure 531-01-009.  Voxel-Wise DCE-MRI for Fibrosis Assessment in Chronic Liver Disease: A Data-Driven Framework Validated Against Histology
Magna Cum Laude
Shan Cai, Alexander Persson, Wolf Bartholomä, Christian Simonsson, Simone Ignatova, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Nils Dahlström, Magnus Borga, Peter Lundberg
Linköping University, Linköping, Sweden
Impact: The proposed data-driven DCE-MRI framework enables voxel-level quantification of dynamic enhancement. It shows potential for fibrosis staging in both whole-liver and regional assessment.
08:38 Figure 531-01-010.  Abdominal Fat Fraction Atlases for Longitudinal Mapping of Liver Fat During Weight Loss: Results from the LION Study
Sophie Starck, Vasiliki Sideri-Lampretsa, Daniela Junker, Mingming Wu, Johannes Raspe, Carmen Blanken, Anna Reik, Hans Hauner, Christina Holzapfel, Dimitrios Karampinos, Daniel Rueckert, Sevgi Gokce Kafali
Technical University of Munich and TUM University Hospital, Munich, Germany
Impact: Proton density fat fraction (PDFF) mapping enables non-invasive liver fat quantification, a biomarker for metabolic diseases. Abdominal PDFF atlases provide voxel-wise, spatially resolved fat distribution characterisation, supporting both population- and individual-level assessment of regional fat changes during weight loss interventions.
08:40 Figure 531-01-011.  Single-breath-hold 3D black-blood imaging for fast and precise myocardial infarction scar assessment
Théo Richard, Soumaya Sridi, Sane Viola, Kalvin Narceau, Victor de Villedon de Naide, Thaïs Génisson, Ewan Barel, Matthias Stuber, Hubert Cochet, Aurelien Bustin
IHU LIRYC, Heart Rhythm Disease Institute, Bordeaux, France
Impact: Requiring only a single breath-hold, the proposed BBFLASH sequence may be clinically useful in addition to bright-blood imaging as a fast and reliable sequence, especially to detect ischemic subendocardial or focal scars and papillary muscle infarction.
08:42 Figure 531-01-012.  Simultaneous Abdominal PDFF and T2-water Mapping at 0.55T using Free-breathing RADGRASE
Brian Toner, Fei Han, Kevin Johnson, Ute Goerke, Shu-Fu Shih, Eze Ahanonu, Timoteo Delgado, Hina Arif Tiwari, Ryan Akhbari, Geoffrey Block, Holden Wu, Vibhas Deshpande, Ali Bilgin, Maria Altbach
University of Arizona, Tucson, United States of America
Impact: We developed a 0.55T free-breathing RADGRASE method to obtain fat-suppressed T2-weighted images, PDFF maps, and T2-water maps from a single acquisition using advanced reconstruction techniques. The approach enables robust, accessible quantitative abdominal MRI.
08:44 Figure 531-01-013.  Robust respiratory motion signal estimation for inversion recovery free-running MR sequence using phase navigator
Hongzhang Huang, Zhenfeng Lyu, Rui Luo, Qinfang Miao, Peng Hu, Haikun Qi
School of Biomedical Engineering, ShanghaiTech University, Shanghai, China
Impact: The proposed phase navigator eliminates the interference of the contrast variations in the quantitative free-running sequence and enables more precise motion correction.
08:46 Figure 531-01-014.  High Spatio-Temporal Resolution T2-weighted LIVE MRI for CSF Flow Assessment in Chiari Malformation
Shiman Wu, Jiahao Gao, yue gao, zhe feng, Zhiwei Qin, Shaofeng Duan, Kan Wang, Zhenwei Yao, Huidong Shi, Chanchan Li, YAN REN
Hushan Hospital, Fudan University, Shanghai, China
Impact: T2-LIVE MRI provided a rapid, intuitive visual assessment of CSF flow obstruction in Chiari I malformation, improving diagnostic certainty and guiding surgical planning. Postoperatively, it enabled efficient confirmation of restored flow and alignment with symptomatic improvement.

08:48 Figure 531-01-015.  Distribution Optimization via Numerical Algorithms (DONA) for Accelerating CEST MRI Acquisition
Magna Cum Laude
Huabin Zhang, Shihao Zeng, Ziyan Wang, Jianpan Huang
The University of Hong Kong, Hong Kong, Hong Kong
Impact: This work establishes a novel, simulation-driven paradigm for optimizing CEST sampling along the saturation frequency dimension. DONA provides a principled and generalizable sparse-sampling strategy as an alternative to fully-sampling scheme, paving the way for clinically feasible, high-speed quantitative CEST MRI.
08:50 Figure 531-01-016.  PaWS: Parallel-transmit Water Suppression pulses towards homogeneous whole-brain MRSI at 7T
Chiara Coletti, Aaron Hess, William Clarke
Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom
Impact: Parallel-transmit Water Suppression (PaWS) schemes can better compensate for B1+ inhomogeneities at 7T than conventional non-pTx schemes. PaWS, universally optimised over a set of B0/B1+ maps from 100 healthy subjects, could enable robust, water-suppressed 7T MRSI across the whole brain.
08:52 Figure 531-01-017.  UTE MRI-Based Quantification of Femoral Trabecular Bone Reveals Age- and Osteoporosis-related changes
Jisook Yi, Arya Suprana, Yankai Meng, Yajun Ma, Eric Chang, Gina Woods, Charles Ginsberg, Saeed Jerban, Jiang Du
University of California, San Diego, United States of America
Impact: 

UTE MRI biomarkers can detect age- and osteoporosis-related trabecular bone deterioration. As a three-dimensional radiation-free method, this approach holds promise for enhancing early risk assessment in patients, especially those classified as osteopenic.

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