Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition - Neuroimaging Signatures Across the Psychiatric Spectrum

Neuroimaging Signatures Across the Psychiatric Spectrum

Digital Poster

Neuro B

Monday, 11 May 2026

Digital Posters Row C

13:50 - 14:45

Session Number: 362-03

No CME/CE Credit

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This session highlights advances in understanding the neurobiological foundations of major psychiatric disorders through multimodal imaging, genetics, and neuroinflammatory markers. Presentations span schizophrenia, PTSD, autism spectrum disorder, and anxiety, revealing shared and disorder‑specific patterns in brain structure, connectivity, excitability, iron regulation, and immune signaling.

		362-03-001. Elevated Serum CCL11 Is Associated with White Matter Microstructural and Tissue Property Changes in Schizophrenia Khin Khin Tha, Maho Kitagawa, Atsuhito Toyomaki, Jakob Assländer, Sebastian Flassbeck, Kentaro Nishigami, Samo Lasic, Shuhei Ishikawa, Karin Bryskhe, Yuta Urushibata, Naoki Hashimoto Hokkaido University, Sappro, Japan Impact: Understanding the link between peripheral CCL11 and white matter alterations in schizophrenia may reveal a biomarker for cognitive deficits and provide insight into mechanisms connecting peripheral inflammation with brain structure.
		362-03-002. Linking Glymphatic Clearance Function to Peripheral Inflammation in Stable Schizophrenia Chengmin Yang, Huilou Liang, wei cui, Su Lui West China Hospital of Sichuan University, Chendu, China Impact: This study reveals a novel inverse relationship between brain glymphatic clearance function and peripheral immune regulation in stable schizophrenia, providing new insights into neuroimmune interactions.
		362-03-003. Trajectory of cerebellar subregion volume reduction in schizophrenia identified from large-scale MRI data Zhaoyun Liu, Zhenyu Huang, Xinjia Lin, Yuchao Jiang Shenzhen University, Shenzhen, China Impact: Revealing cerebellar atrophy heterogeneity enables schizophrenia researchers and clinicians to pursue precision-targeted treatment clinically;
		362-03-004. QSM and R2* Reveal Genetic Effects on Brain Iron in Psychotic-Like Experiences Marisleydis Garcia, Eduardo Perez-Palma, Camilo Villamán, Gabriela Repetto, Nicolás Crossley, Carlos Milovic, Cristian Tejos Universidad de Santiago de Chile, Santiago, Chile Impact: These findings provide novel evidence linking genetic risk for PLEs to altered subcortical brain iron. Combining QSM with PGS offers a promising approach to identify early neurobiological markers underlying vulnerability to PLEs in population-based samples.
		362-03-005. Altered Structural-Functional Coupling in Post-Traumatic Stress Disorder are Associated with Neurobiological Profiles Yujie Song, Bin Guo, Bin Huang, Qiyong Gong State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Address: No.1, Shuaifuyuan, Dongcheng District, Beijing 100730, China Impact: By integrating macroscale in vivo imaging with microscale biological substrates, this study advance the understanding of structure-function coupling in the psychopathology of post-traumatic stress disorder and may help to establish targeted diagnosis and treatment measures.
		362-03-006. Distinct Cortical and White-Matter Microstructural Signatures Differentiate PTSD and Complex PTSD Chrystal Douflias, Alice Mok, Xuqian Li, Joshua Flavell, Fiona Maccallum, Julie Henry, Lena Oestreich The University of Queensland, Brisbane, Australia Impact: Surface-based analyses and advanced diffusion modeling reveal unique cortical and microstructural patterns that differentiate PTSD from CPTSD, supporting their nosological distinction and emphasizing the potential of surface-based and diffusion imaging for future biomarker-based diagnosis and treatment stratification.
		362-03-007. Thalamic Microstructural Deficits in Young Adults with Autism Spectrum Disorder Beatrice Lattanzi, Faye McKenna, Mariana Lazar Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, United States of America Impact: Thalamic microstructure is associated with core autism spectrum disorder (ASD) deficits. Mean kurtosis may serve as a biomarker of thalamic development and integrity in ASD. These results improve upon current knowledge of ASD neuropathology and its assessment.
		362-03-008. Amygdala Connectivity Alterations in Generalized Anxiety Disorder: From Static and Dynamic to Effective Connectivity Dingmei Deng, Weijie Bao, Hailong Li, YingXue Gao, Shuangwei Chai, Xiaoqi Huang Huaxi MR Research Center (HMRRC), Institute of Radiology and Medical Imaging, West China Hospital of Sichuan University, Chengdu, China Impact: This multilevel framework reveals interconnected alterations across static, dynamic, and effective connectivity, reflecting disrupted top-down control in GAD. It offers mechanistic insight into emotion regulation deficits and intervention targets in anxiety disorders.
		362-03-009. Tri-Modal Brain Connectivity Fusion Improves Prediction of Trait anxiety levels SungChul JUNG, Dong-Hyun Kim Yonsei University, Seoul, Korea, Republic of Impact: A tri-modal approach delivers improved predictive performance for psychological traits by overcoming unimodal blind spots. The improvements can simplify risk screening and follow-up monitoring alongside conventional questionnaires and clinical interviews, reducing burden and enabling earlier, data-driven decision support.
		362-03-010. An Exploratory Study of Brain Structure and Functional Network Connectivity Mechanisms in Anxiety-Prone Individuals Using sMR Sijia Li, Jingming Jiang, Hanjiaerbieke Kukun, rui xu, Wei Sheng, Yunling Wang Impact: Cortical thickness may serve as a quantitative MRI biomarker for assessing anxiety severity, enabling convenient evaluation and providing new insights into neural mechanisms, while functional connectivity appears less affected in anxiety-prone individuals.