This session provides an overview of advanced MRI neuroimaging with a focus on Chemical Exchange Saturation Transfer (CEST) and Amide Proton Transfer (APT) imaging in brain disorders across different magnetic field strengths. The biophysical principles underlying CEST and APT contrast will be introduced, followed by discussion of their implementation at clinical (3T, 5T) and ultra-high-field (7T) MRI. Emphasis will be placed on how field strength influences sensitivity, spectral separation, signal-to-noise ratio, and quantitative accuracy, as well as associated technical challenges such as B₀/B₁ inhomogeneity and SAR. The session will highlight applications of APT and CEST MRI in neurological conditions including brain tumours and stroke. Comparative studies across field strengths will illustrate trade-offs between clinical feasibility and molecular sensitivity. The session will conclude with perspectives on quantification, reproducibility, and translation of CEST and APT techniques into routine neuroimaging.