Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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462-01-001.
Delineation and Characterization of Magnetization Transfer Attenuated Tumour Sub-Regions using Unsupervised Clustering
Impact: This work introduces the first to my knowledge, automated framework for delineating MT-attenuated tumour sub-regions in brain metastases, enabling biologically informed target definition for stereotactic radiosurgery and improving understanding of intra-tumour heterogeneity through MRI signal derived habitats.
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462-01-002.
Assessment of glioma biomarkers using amide proton transfer weighted MRI with and without fluid suppression
Impact: These
promising findings indicate that APTw MRI with patient-specific fluid
suppression enhances biomarker prediction. This approach could decrease the
need for invasive biopsies and serve as an alternative, particularly
considering tumor heterogeneity.
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462-01-003.
Dynamic PCASL angiography using a 3D-radial multi-spoke SPGR sequence: Comparing multi-label duration and dynamic readouts
Impact: This study substantially improves
the SNR and robustness of dynamic PCASL angiography, providing a more flexible
and clinically viable tool for diagnosing cerebral vascular malformations. This
is a key step toward clinical adoption.
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462-01-004.
Pilot MRI Study for Evaluating Articular Cartilage Injury Using Intra-Articular 17O-Labeled Water in Ex Vivo Porcine Knees
Impact: This
study demonstrates a novel MRI-based approach using 17O-labeled
water and T2 mapping to visualize and quantify water permeability changes in
articular cartilage, offering potential as an early imaging biomarker for
osteoarthritis.
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462-01-005.
Reducing ASL Signal Dropout at 3 Tesla and 7 Tesla Using Spiral In-Out Trajectories
Impact: 3D stack-of-spirals
allows whole-brain coverage in arterial spin labeling imaging but suffers from
signal loss due to long readout and long echo trains. Spiral
in-out trajectories can mitigate signal loss, which is particularly helpful in few-shot acquisitions.
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462-01-006.
A Multimodal MRI Study Reveals Thalamic Neurovascular-Neurochemical Decoupling in Classical Trigeminal Neuralgia
Impact: This
study suggests thalamic neurovascular-neurochemical decoupling as a core
feature of CTN. The findings provide a novel pathophysiological framework and
promising biomarkers for developing targeted, dimension-specific therapies.
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462-01-007.
Quantitative Assessment of Iron Deposition in Subcortical Nuclei of Epilepsy Patients Using 7 Tesla MRI
Impact: 7T quantitative susceptibility mapping enables sensitive detection
of subcortical iron abnormalities, advancing biomarker discovery and precision
monitoring in epilepsy.
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462-01-008.
Multi-site, Multi-Vendor Quality Assurance Phantom Validation for 129Xe MRI Clinical Trials Consortium Protocols
Impact: A simple,
quantitative 129Xe gas phantom is proposed to enable reproducible, standardized
quality assurance across scanners, providing a robust validation tool for
harmonized clinical protocols and future ¹²⁹Xe MRI sequence and reconstruction
development.
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462-01-009.
Collaborative Multi-site Preclinical MRS Study (CoMP-MRS) – Preliminary Results
Impact: CoMP-MRS is an international consortium aimed at establishing evidence-based best practices in preclinical MRS. In this preliminary study, we identify factors affecting spectral quality in rodent ¹H-MRS. This work will promote standardization in preclinical MRS, improving reproducibility and data quality.
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462-01-010.
Evaluating QSM based methods for estimating [Gd] in breast DCE-MRI across a range of temporal resolutions
Impact: Reliable and reproducible estimates of contrast agent concentration are crucial for accurate measurement of tumor perfusion parameters on MRI.
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462-01-011.
Abdominal T1 mapping at 7 T
Impact: This study provides the first comprehensive reference dataset of
abdominal T1 values at 7 T using a simple, robust GRE-IR method with
B1⁺ shimming. The measured T1
values have the potential to serve in advanced
quantitative techniques and simulations.
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462-01-012.
MRI in Clinical Practice: Diagnosis of Intrapancreatic Splenule with Ferumoxytol MRI
Impact: Ferumoxytol, a SPIO based MR contrast agent, can be used to diagnose intrapancreatic splenule below the threshold for detection by the traditional nuclear medicine sulfur colloid scan, avoiding further imaging workup, radiation exposure, and unnecessary treatment.
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462-01-013.
Dynamic Multi-Temporal APTw and ADC Histogram Analysis for Early Prediction of Neoadjuvant Chemoradiotherapy Response in Loca
Impact: Dynamic multi-temporal APTw and ADC histogram
analysis enables noninvasive and interpretable early prediction of treatment
response in rectal cancer, providing a practical imaging biomarker for adaptive
therapy planning and improving clinical decision-making in personalized
oncology.
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462-01-014.
Linking in vivo Cortical Structure and Function via High-Resolution Diffusion and Perfusion Imaging
Impact: This work develops a simplified SANDI model for cortical microstructure mapping. Validated against histology, it establishes the fsphere metric as a promising, non-invasive metric for cortical soma density, potentially enabling new studies of coupling mechanism of brain structure and function.
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462-01-015.
Enabling Routine Lung Imaging in a Resource-Limited Setting Using Pseudo-UTE Lung MRI at 0.55T
Impact: A readily available STAR-VIBE sequence at 0.55T uses radial sampling and short 2.3 ms TE to provide lung imaging. This enables practical lung MRI access in routine clinical settings, especially when only one cross-sectional modality is feasible in resource-constrained environments.
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© 2026 International Society for Magnetic Resonance in Medicine