Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Contrast Mechanisms Potpourri Including Registered/Clinical Abstracts

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Contrast Mechanisms Potpourri Including Registered/Clinical Abstracts
Digital Poster
Contrast Mechanisms
Tuesday, 12 May 2026
Digital Posters Row C
08:20 - 09:15
Session Number: 462-01
No CME/CE Credit
This session combines a diverse range of research on clinical imaging, flow, magnetization transfer, susceptibility contrasts featuring registered and clinical focus abstracts.

  Figure 462-01-001.  Delineation and Characterization of Magnetization Transfer Attenuated Tumour Sub-Regions using Unsupervised Clustering
Céline Dubroy-McArdle, Wilfred Lam, Greg Stanisz, Dafna Sussman
Toronto Metropolitan University, Toronto, Canada
Impact: This work introduces the first to my knowledge, automated framework for delineating MT-attenuated tumour sub-regions in brain metastases, enabling biologically informed target definition for stereotactic radiosurgery and improving understanding of intra-tumour heterogeneity through MRI signal derived habitats.
  Figure 462-01-002.  Assessment of glioma biomarkers using amide proton transfer weighted MRI with and without fluid suppression
Malte Knutsson, Tim Salomonsson, Anina Seidemo, Faris Durmo, Anna Rydelius, Xavier Sarda, Patrick Liebig, Mattias Belting, Johan Bengzon, Peter van Zijl, Linda Knutsson, Pia Maly Sundgren
Lund University, Lund, Sweden
Impact: These promising findings indicate that APTw MRI with patient-specific fluid suppression enhances biomarker prediction. This approach could decrease the need for invasive biopsies and serve as an alternative, particularly considering tumor heterogeneity.
  Figure 462-01-003.  Dynamic PCASL angiography using a 3D-radial multi-spoke SPGR sequence: Comparing multi-label duration and dynamic readouts
Andreas Petrovic, Shalini Amukotuwa, Andrew Gauden, Leon Lai, Martin Soellradl, Thomas Okell, Roland Bammer
Monash University, Melbourne, Australia
Impact: This study substantially improves the SNR and robustness of dynamic PCASL angiography, providing a more flexible and clinically viable tool for diagnosing cerebral vascular malformations. This is a key step toward clinical adoption.
  Figure 462-01-004.  Pilot MRI Study for Evaluating Articular Cartilage Injury Using Intra-Articular 17O-Labeled Water in Ex Vivo Porcine Knees
Hiroyuki Kameda, Minami Shimoma, Taro Fujiwara, Shotaro Fuchibe, Taro Igarashi, Yoshitaka Bito, Kazuyuki Minowa, Kohsuke Kudo
Hokkaido University, Sappro, Japan
Impact: This study demonstrates a novel MRI-based approach using 17O-labeled water and T2 mapping to visualize and quantify water permeability changes in articular cartilage, offering potential as an early imaging biomarker for osteoarthritis.
  Figure 462-01-005.  Reducing ASL Signal Dropout at 3 Tesla and 7 Tesla Using Spiral In-Out Trajectories
Yulin Chang, Manuel Taso, Wei-ching Lo, Nutandev Bikkamane Jayadev, Jan Kufer, Meher Juttukonda, Marta Vidorreta, Stephen Cauley, Ze Wang, John Detre
Siemens Medical Solutions USA Inc., Boston, United States of America
Impact: 3D stack-of-spirals allows whole-brain coverage in arterial spin labeling imaging but suffers from signal loss due to long readout and long echo trains. Spiral in-out trajectories can mitigate signal loss, which is particularly helpful in few-shot acquisitions.
  Figure 462-01-006.  A Multimodal MRI Study Reveals Thalamic Neurovascular-Neurochemical Decoupling in Classical Trigeminal Neuralgia
jingqi Jiang, Danyang Wang, Pengfei Zhang, Kai AI, Jing Zhang
Department of Magnetic Resonance, Lanzhou, China
Impact: This study suggests thalamic neurovascular-neurochemical decoupling as a core feature of CTN. The findings provide a novel pathophysiological framework and promising biomarkers for developing targeted, dimension-specific therapies.
  Figure 462-01-007.  Quantitative Assessment of Iron Deposition in Subcortical Nuclei of Epilepsy Patients Using 7 Tesla MRI
Fei Zhu, Yingying Tang, Bo Tao, Huilou Liang, Su Lui
West China Hospital of Sichuan University, Chendu, China
Impact: 7T quantitative susceptibility mapping enables sensitive detection of subcortical iron abnormalities, advancing biomarker discovery and precision monitoring in epilepsy.
  Figure 462-01-008.  Multi-site, Multi-Vendor Quality Assurance Phantom Validation for 129Xe MRI Clinical Trials Consortium Protocols
Mariah Costa, Conner Wharff, Riley Meyer, Saman Khodaei, Andrew Hahn, Abhilash Kizhakke Puliyakote, Sean Fain
University of Iowa, Iowa City, United States of America
Impact: A simple, quantitative 129Xe gas phantom is proposed to enable reproducible, standardized quality assurance across scanners, providing a robust validation tool for harmonized clinical protocols and future ¹²⁹Xe MRI sequence and reconstruction development.
  Figure 462-01-009.  Collaborative Multi-site Preclinical MRS Study (CoMP-MRS) – Preliminary Results
Diana G. Rotaru, Mark Mikkelsen, Georg Oeltzschner, Thanh Phong Lê, Colleen Bailey, Emma Van Praagh, Eloise Mougel, Joanes Grandjean, Jamie Near, Cristina Cudalbu, the CoMP-MRS consortium
Medical University of Vienna, Vienna, Austria
Impact: CoMP-MRS is an international consortium aimed at establishing evidence-based best practices in preclinical MRS. In this preliminary study, we identify factors affecting spectral quality in rodent ¹H-MRS. This work will promote standardization in preclinical MRS, improving reproducibility and data quality.
  Figure 462-01-010.  Evaluating QSM based methods for estimating [Gd] in breast DCE-MRI across a range of temporal resolutions
Martin Kostal, Gene Kim, Pascal Spincemaille , Alexey Dimov, Yi Wang
Weill Cornell Medicine, New York, United States of America
Impact: Reliable and reproducible estimates of contrast agent concentration are crucial for accurate measurement of tumor perfusion parameters on MRI.
  Figure 462-01-011.  Abdominal T1 mapping at 7 T
Petr Bulanov, Johannes Grimm, Petr Menshchikov, Simon Schmidt, Stephan Orzada, Mark Ladd, Sebastian Schmitter
Heidelberg University, Heidelberg, Germany
Impact: This study provides the first comprehensive reference dataset of abdominal T1 values at 7 T using a simple, robust GRE-IR method with B1⁺ shimming. The measured T1 values have the potential to serve in advanced quantitative techniques and simulations.
  Figure 462-01-012.  MRI in Clinical Practice: Diagnosis of Intrapancreatic Splenule with Ferumoxytol MRI
Sunny Rishi, Vipul Sheth
Stanford Medicine, Stanford, United States of America
Impact: Ferumoxytol, a SPIO based MR contrast agent, can be used to diagnose intrapancreatic splenule below the threshold for detection by the traditional nuclear medicine sulfur colloid scan, avoiding further imaging workup, radiation exposure, and unnecessary treatment.
  Figure 462-01-013.  Dynamic Multi-Temporal APTw and ADC Histogram Analysis for Early Prediction of Neoadjuvant Chemoradiotherapy Response in Loca
Yingying Zhang, Gang Huang
Gansu University of Chinese Medicine, Lanzhou, China
Impact: Dynamic multi-temporal APTw and ADC histogram analysis enables noninvasive and interpretable early prediction of treatment response in rectal cancer, providing a practical imaging biomarker for adaptive therapy planning and improving clinical decision-making in personalized oncology.
  Figure 462-01-014.  Linking in vivo Cortical Structure and Function via High-Resolution Diffusion and Perfusion Imaging
Tanxin Dong, Fanhua Guo, Hong Hsi Lee, Chenyang Zhao, Susie Huang, Danny Wang
University of Southern California, Los Angeles, United States of America
Impact: This work develops a simplified SANDI model for cortical microstructure mapping. Validated against histology, it establishes the fsphere metric as a promising, non-invasive metric for cortical soma density, potentially enabling new studies of coupling mechanism of brain structure and function.
  Figure 462-01-015.  Enabling Routine Lung Imaging in a Resource-Limited Setting Using Pseudo-UTE Lung MRI at 0.55T
Devasenathipathy Kandasamy, Yatin sharma, Vikas Gulani, Benjamin Schmitt, Raju Sharma
All India Institute of Medical Sciences, New Delhi, India
Impact: A readily available STAR-VIBE sequence at 0.55T uses radial sampling and short 2.3 ms TE to provide lung imaging. This enables practical lung MRI access in routine clinical settings, especially when only one cross-sectional modality is feasible in resource-constrained environments.

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