Impact: This work enables clinicians to non-invasively differentiate true tumor progression from pseudopgression, guiding personalized therapy. It uniquely probes cellular-scale microstructural evolution in vivo, directly impacting patient survival and quality of life.

Impact: Both increased fALFF and ReHo may serve as imaging markers of early brain functional alterations in non-NPSLE, with fALFF demonstrating higher sensitivity and potential efficacy for detecting subtle neural compensatory changes.

Impact: χ-separation decomposes subvoxel magnetic susceptibility sources, enabling in vivo differentiation between iron deposition and myelin alterations in Parkinson’s disease, thereby providing new quantitative biomarkers for neurodegeneration and cognition-related pathophysiology.

Impact: Clustering periventricular nodular heterotopia based on connectivity patterns to other brain regions may help guide stereo-EEG (SEEG) implantation planning, ensuring that each cluster and its connected regions are sampled by SEEG to avoid omission of potential epileptogenic areas.

Impact: Visual stimulation-evoked vascular reactivity is impaired in patients with Cerebral Amyloid Angiopathy. It remains unclear whether reduced vascular reactivity is linked to impaired cerebrospinal fluid dynamics. Interrogating this relationship with non-invasive MRI will help with our understanding of these phenomena.

Impact: This study shows neural inefficiency signatures in FMS and LC, with altered network integration and recovery after mild exertion, offering a potential biomarker for central dysregulation across chronic conditions.

Impact: To enhance the understanding of spontaneous brain activity patterns of tremor-dominant Parkinson’s disease (TD) and essential tremor (ET), and to facilitate more effective differentiation between these two conditions

Impact: This study identified fetal head descending thrust as an objective predictor for emergency caesarean section and revealed distinct spontaneous neural activity alterations in PP-PTSD patients, providing a novel strategy for preemptive psychological intervention and enhancing the understanding of PP-PTSD neuropathology.

Impact: The research on the prediction model of myocardial injury has a profound impact on clinical practice, patient prognosis, medical resource allocation, and scientific research transformation by filling the gap in clinical diagnosis, optimizing treatment strategies, and promoting mechanism exploration.

Impact: Our findings in a longitudinal sample of cognitively intact APOE ε4 carriers add to the literature on resting state functional connectivity changes in preclinical Alzheimer’s disease. These early changes may point to mechanisms of AD-related cognitive decline.

Impact: TBI may cause brain structural damage, impair glymphatic function, and subsequently affect patients' levels of consciousness. These findings further indicate that glymphatic dysfunction could play an important role in the pathogenesis and prognosis of disorders of consciousness.

Impact: Transcutaneous auricular vagus nerve stimulation (taVNS) may alleviate insomnia by lowering functional connectivity (FC) between salience and task‑positive networks and within the cingulo‑opercular network. Baseline left insula‑visual/auditory FC could predict taVNS treatment response.

Impact: This study demonstrated a voxel-level functional mapping method that improved efficiency and accuracy for preoperative brain tumor planning with minimal quantities of rs-fMRI data, offering potential for enhancing clinical workflows, improving patient comfort, and enabling individualized brain tumor treatment planning.

Impact: Patients with insomnia and comorbid depression show distinct patterns of glymphatic dysfunction and neurotransmitter imbalance. Coexisting depression may worsen glymphatic impairment, highlighting the need for early intervention and cautious use of GABA receptor agonists in treatment.

Impact: The imbalance between glutamate and glutamine, along with decreased tNAA and myo-inositol concentrations, may serve as potential biomarkers for identifying the acute phase of MELAS, offering new perspectives for its diagnosis and clinical management.