This digital poster session brings together cutting-edge research on the brain’s fluid and barrier systems in neuroinflammation. Presentations highlight advanced neuroimaging techniques and their application to multiple sclerosis, NMOSD, and other neuroinflammatory conditions. Collectively, the posters explore how alterations in neurofluid dynamics and microenvironment contribute to inflammation, tissue injury, and clinical outcomes, offering emerging biomarkers and potential translational insights.